Iliac crest bone graft

髂骨植骨
  • 文章类型: Case Reports
    胫骨骨折的愈合经常引起人们的关注。在一个这样的案例中,一名62岁的女性患者出现在我们的急诊室(ER),因交通事故导致胫骨干phy端粉碎性骨折。患者在接下来的两年中接受了三次外科手术。第一种干预是使用钢板和螺钉的切开复位内固定(ORIF)。第二次干预,第一次手术后三个月,通过顺行胫骨髓内钉移除植入物并闭合复位和内固定(CRIF)解决了愈合延迟。第三次干预通过使用近端胫骨锁定板和螺钉移除断裂的胫骨钉和ORIF,解决了植入物失败和少营养骨不连。增强腓骨轴和扩骨自体移植物。我们对患者进行了频繁的随访,并进行了多次X射线检查以确认和监测骨折愈合。在最后一次随访中,在上次手术干预两年后,想象检查显示患者出现骨折愈合,她可以在手术的腿上支撑她的全身重量,能够走路和进行正常的日常活动。因此,我们得出结论,所选择的手术方法(ORIF与胫骨近端锁定钢板和螺钉,用腓骨轴支柱和扩骨自体移植物增强)是治疗高能量粉碎性胫骨骨折中无菌性营养不良性骨不连的可行选择。
    The union of tibial fractures often raises concerns. In one such case, a 62-year-old female patient presented in our Emergency Room (ER) with a comminuted tibial metaphyseal fracture resulting from a traffic accident. The patient underwent three surgical procedures in the following two years. The first intervention was open reduction internal fixation (ORIF) with a plate and screws. The second intervention, which took place three months after the first surgery, addressed the union delay through implant removal and closed reduction and internal fixation (CRIF) with an antegrade intramedullary tibial nail. The third intervention addressed the implant failure and oligotrophic nonunion through the removal of the broken tibial nail and ORIF using a proximal tibia locking plate and screws, augmented with fibular shaft and reamed iliac crest autografts. We conducted frequent follow-ups with the patient and performed multiple X-rays to confirm and monitor the fracture union. At the last follow-up, two years after the last surgical intervention, imagistic investigations showed that the patient presented with fracture union, she could support her full body weight on the operated leg, and was able to walk and carry out normal daily activities. As such, we concluded that the surgical method chosen (ORIF with proximal tibia locking plate and screws, augmented with a fibula shaft strut and reamed iliac crest autograft) was a viable option to treat an aseptic oligotrophic nonunion in a high-energy comminuted tibia fracture.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    后盂骨丢失(pGBL)通常与肩关节后不稳定有关。肩关节后路不稳定占肩关节病变的一小部分,和严重的骨丢失后不稳定在文献中还没有很好的定义。参与重复强调肩部后部稳定结构的活动的年轻患者群体更容易发生后部肩部不稳定。已经描述了多种手术选择,从孤立的囊膜修复到关节盂截骨术。在pGBL的情况下,单独的软组织修复可能是不充分的治疗,并且使患者处于高复发风险中。在pGBL的情况下,我们首选的后关节盂重建技术包括将游离的the骨移植物转移到天然关节盂上。移植物的轮廓适合骨缺损并固定以提供关节盂轨道的延伸。在这项研究中,我们回顾了pGBL在后部不稳定的背景下,并详细描述了我们的技术。需要进一步的长期研究来完善关节盂骨移植手术的适应症,并量化构成关键pGBL的因素。
    Posterior glenoid bone loss (pGBL) is frequently associated with posterior shoulder instability. Posterior glenohumeral instability accounts for a small percentage of shoulder pathologies, and critical bone loss in posterior instability has not been well defined in the literature. Younger patient populations who participate in activities that repetitively stress the posterior stabilizing structures of the shoulder are more prone to developing posterior shoulder instability. A variety of surgical options have been described, ranging from isolated capsulolabral repair to glenoid osteotomy. Soft-tissue repair alone may be an inadequate treatment in cases of pGBL and places patients at a high risk of recurrence. Our preferred technique for posterior glenoid reconstruction in cases of pGBL involves the transfer of a free iliac crest bone graft onto the native glenoid. The graft is contoured to fit the osseous defect and secured to provide an extension of the glenoid track. In this study, we review pGBL in the setting of posterior instability and describe our technique in detail. Further long-term studies are needed to refine the indications for glenoid bone graft procedures and quantify what constitutes a critical pGBL.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • DOI:
    文章类型: Randomized Controlled Trial
    BACKGROUND: spinal fusion is used to treat, among other pathologies, the degenerative intervertebral disc disease. Autologous iliac crest bone grafting is the golden standard treatment for increasing the rate of fusion; however, it isn\'t free of complications.
    OBJECTIVE: to investigate whether patients who have posterior iliac crest graft harvesting and are blinded to the donor site, can identify from which side the graft was harvested, and whether the intensity of this pain is related to the amount of graft obtained.
    METHODS: prospective, experimental, randomized and comparative, single-blind study. Adult patients who underwent primary instrumented open posterolateral lumbar fusion with autologous iliac crest bone graft between July 2019 and April 2020 were included. Patients were divided into two randomized groups. The amount of graft to be harvested was according to surgical needs. The patients were asked about pain according to the visual analogue scale in the first, third and sixth months after surgery, always requesting that the most painful side be identified.
    RESULTS: a total of 44 patients (n = 23 right crest, n = 21 left crest) were analyzed. Most patients were unable to identify the side from which the bone graft was harvested, with a statistically significant difference (p-value 0.0001).
    CONCLUSIONS: iliac crest bone graft harvesting is an effective and safe procedure that improves the rates of fusion without increasing the patient\'s morbidity.
    UNASSIGNED: la fusión espinal es utilizada para tratar, entre otras patologías, las enfermedades degenerativas discales. El injerto óseo autólogo de cresta ilíaca es el estándar de oro para aumentar las probabilidades de fusión; sin embargo, no está exento de complicaciones.
    OBJECTIVE: investigar si los pacientes a los que se les recolecta injerto de cresta ilíaca posterior y son cegados al lado del sitio donante, pueden identificar de qué lado se tomó dicho injerto y si la intensidad de este dolor está en relación con la cantidad de injerto obtenido.
    UNASSIGNED: trabajo prospectivo, experimental, aleatorizado y comparativo, simple ciego. Se incluyeron pacientes adultos operados entre Julio de 2019 hasta Abril de 2020, a los cuales se les realizó una cirugía primaria de artrodesis lumbar posterolateral abierta instrumentada, con colocación de injerto óseo autólogo de cresta ilíaca. Se dividió a los pacientes en dos grupos aleatorizados. La cantidad de injerto a recolectar fue de acuerdo a las necesidades quirúrgicas. Se interrogó por el dolor según escala visual analógica al primer, tercer y sexto mes de la cirugía, siempre solicitando que se identifique el lado más doloroso.
    RESULTS: se analizaron 44 pacientes (n = 23 cresta derecha, n = 21 cresta izquierda). La mayoría de los pacientes no lograron identificar el lado del cual se obtuvo el injerto óseo, con una diferencia estadística ampliamente significativa (p = 0.0001).
    UNASSIGNED: la obtención de injerto óseo de cresta ilíaca es un procedimiento efectivo y seguro, que mejora las probabilidades de fusión sin aumentar la morbilidad del paciente.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    目的:介绍采用大骨骨移植治疗严重胫骨骨缺损的方法和经验。
    方法:从2020年1月至2022年1月,对20例严重胫骨骨缺损患者(10名男性和10名女性)进行了骨移植。骨缺损的平均长度为13.59±3.41。收获双侧髂骨移植物,包括髂棘的内外板。皮质骨螺钉用于将两个髂骨块整合成一个复合体。锁定板用于固定移植物-宿主复合物,必要时辅以重建板,以增加稳定性。在随访时通过X线照片上的皮质骨融合评估骨愈合,通过VAS评分评估髂痛,通过ODI评分评估下肢功能。并发症也被考虑在内。
    结果:平均随访时间为27.4±5.6(范围24-33个月),平均VAS评分为8.8±1.9,平均ODI评分为11.1±1.8,植骨区皮质骨融合数为3.5±0.5。在所有the骨移植宿主部位的病例中均获得了令人满意的融合。没有骨不连,所有病例均出现移位或骨折。没有观察到需要二次手术的感染和骨吸收。一名患者有大脚趾背屈无力。在2例患者中观察到了足背的感觉减退。3例患者出现踝关节僵硬和水肿。通过物理治疗和康复训练,并发症得到明显改善。
    结论:对于严重大小的胫骨骨缺损,治疗方法多种多样。在本文中,我们通过使用大的髂骨移植治疗骨缺损,获得了满意的效果。这种方法不仅可以恢复胫骨的完整性,而且内固定也获得了良好的稳定性,和操作技能更容易被外科医生接受。因此,它为临床医生提供了一种替代的手术方法。
    OBJECTIVE: To introduce the method and experience of treating critical-sized tibial bone defect by taking large iliac crest bone graft.
    METHODS: From January 2020 to January 2022, iliac crest bone grafting was performed in 20 patients (10 men and 10 women) with critical-sized tibial bone defect. The mean length of bone defect was 13.59 ± 3.41. Bilateral iliac crest grafts were harvested, including the inner and outer plates of the iliac crest and iliac spine. The cortical bone screw was used to integrate two iliac bone blocks into one complex. Locking plate was used to fix the graft-host complex, supplemented with reconstruction plate to increase stability when necessary. Bone healing was evaluated by cortical bone fusion on radiographs at follow-up, iliac pain was assessed by VAS score, and lower limb function was assessed by ODI score. Complications were also taken into consideration.
    RESULTS: The average follow-up time was 27.4 ± 5.6 (Range 24-33 months), the mean VAS score was 8.8 ± 1.9, the mean ODI score was 11.1 ± 1.8, and the number of cortical bone fusion in the bone graft area was 3.5 ± 0.5. Satisfactory fusion was obtained in all cases of iliac bone transplant-host site. No nonunion, shift or fracture was found in all cases. No infection and bone resorption were observed that need secondary surgery. One patient had dorsiflexion weakness of the great toe. Hypoesthesia of the dorsal foot was observed in 2 patients. Ankle stiffness and edema occurred in 3 patients. Complications were significantly improved by physical therapy and rehabilitation training.
    CONCLUSIONS: For the cases of critical-sized tibial bone defect, the treatment methods are various. In this paper, we have obtained satisfactory results by using large iliac bone graft to treat bone defect. This approach can not only restore the integrity of the tibia, but also obtain good stability with internal fixation, and operation skills are more acceptable for surgeons. Therefore, it provides an alternative surgical method for clinicians.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    自体骨移植是骨科常见的手术方法。前髂骨是采集自体骨移植物的常见部位。采集髂骨后有很多并发症,供体部位的疼痛和不适是最常见的后遗症。然而,髂骨采集后肠破裂尚未见报道。我们报告了一名58岁的男性在从the骨采集骨后发生盲肠破裂的病例。经过适当的手术修复,患者从ICU出院,肠道功能恢复.从the骨获取骨的这种严重并发症促使人们对the骨获取和供体部位重建技术进行了研究。
    Autogenous bone grafting is a common surgical method in orthopaedics. The anterior iliac crest is a common site for harvesting autologous bone grafts. There are many complications after iliac bone harvesting, and pain and discomfort at the donor site are the most common sequelae. However, intestinal rupture after iliac bone harvesting has not been reported. We report a case of caecum rupture in a 58-year-old male after harvesting bone from his iliac crest. After proper surgical repair, the patient was discharged from the ICU and his bowel function recovered. This serious complication of bone harvesting from the iliac crest prompted investigation of the technique of iliac crest harvesting and donor site reconstruction.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    背景:石骨病包括一组罕见的遗传性疾病,并导致骨结构异常。由于破骨细胞无功能或缺乏,因此骨重塑受到极大抑制。这种情况导致骨骼过度生长,骨髓消失,导致再生障碍性贫血;颅骨神经通道阻塞会导致失明和听力损害。在大多数情况下,骨硬化导致口腔并发症,如牙齿变形,低矿化,牙齿萌出延迟或缺失。唯一的治愈性治疗是造血干细胞移植(HSCT)。儿童期和青春期口腔并发症的主要治疗包括通过预防性治疗来保护萌出的牙齿免受龋齿疾病的侵害,所述预防性治疗旨在通过一生中频繁的定期牙科就诊来实现最佳的口腔卫生。许多患有骨硬化症的患者需要主要的口腔康复来治疗该疾病的并发症。HSCT的改善结果增加了牙科专业人员遇到石骨症患者的可能性。
    方法:在本案例报告中,我们表明,患有严重口腔并发症的石骨症患者,如果在早期接受石骨症治疗,可以成功治疗。这个男孩在儿科接受了牙齿护理,并定期举行多学科会议,以制定未来的治疗计划。15岁时,他被转介康复。初步评估显示牙槽骨没有进一步生长。康复是逐步进行的,拔除畸形和错位的牙齿。最初,患者接受了可摘局部义齿,然后重建了牙槽突的宽度,钛植入物,临时固定桥,最后是螺丝保留的钛陶瓷桥,带有上下颚的钛框架。
    结论:负荷后的三年随访表明,由于频繁的专业口腔卫生护理,边缘骨水平稳定,口腔卫生最佳。患者没有表现出来自颞下颌关节的症状迹象,并且已经适应了新的颌骨关系,没有任何功能或语音问题。
    Osteopetrosis comprises a group of inherited disorders that are rare and result in abnormal bone structure. Bone remodeling is extremely inhibited because osteoclasts are nonfunctional or lacking. This condition causes overgrowth of bone with disappearance of the bone marrow, leading to aplastic anemia; obstruction of nerve passages in the skull leads to blindness and often hearing impairment. In most cases, osteopetrosis results in oral complications such as tooth deformation, hypomineralization, and delayed or absent tooth eruption. The only curative treatment is hematopoietic stem cell transplantation (HSCT). The main treatment of the oral complications during childhood and adolescence consists in protecting the erupted teeth against caries disease through prophylactic treatment aimed at optimal oral hygiene through frequent regular dental visits throughout life. Many patients with osteopetrosis require major oral rehabilitation to treat complications of the disease. Improved results of HSCT increase the likelihood that dental professionals will encounter patients with osteopetrosis.
    In this case report, we show that individuals with osteopetrosis who have severe oral complications can be treated successfully if they are treated for osteopetrosis at an early age. The boy had his dental care in pedodontics, and regular multidisciplinary meetings were held for future treatment planning. At the age of 15, he was then referred for rehabilitation. The initial evaluations revealed no further growth in the alveolar bone. The rehabilitation was done stepwise, with extraction of malformed and malpositioned teeth. Initially, the patient received a removable partial denture followed by reconstruction of the width of the alveolar process, titanium implants, temporary fixed bridges, and finally screw-retained titanium-ceramic bridges with titanium frames for the upper and lower jaws.
    The three-year follow-up after loading indicated a stable marginal bone level and optimal oral hygiene as a result of frequent professional oral hygiene care. The patient showed no signs of symptoms from the temporomandibular joint and has adapted to the new jaw relation without any functional or phonetical issues.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    有几篇文章支持使用松质骨骨移植治疗锁骨不愈合;但是,关于在锁骨骨不连伴骨丢失的情况下使用三皮质髂棘移植物的文献很少。当它被研究时,三皮质移植已被证明可以在锁骨中产生放射学证实的结合,让患者对最终结果感到满意。我们介绍了两例锁骨骨折不愈合的病例,这些病例成功地通过三皮质介入植骨治疗。在第一种情况下,一名45岁女性出现萎缩性左锁骨中段骨折骨不连,硬件失败,此前曾两次尝试内固定均未实现愈合.她接受了结构性介入骨移植和钢板固定治疗,并通过放射学骨折愈合恢复了手臂的完全无痛功能。在第二种情况下,一名50岁的男性在左锁骨中段骨折后出现急性稳定,随后对不工会进行了修改,但没有成功,导致骨丢失的持续性骨不连。他接受了三皮质骨移植和钢板固定治疗。从手术开始的培养物确实生长了表皮葡萄球菌和痤疮丙酸杆菌,他接受了静脉注射万古霉素治疗六周。病人的锁骨继续愈合,他恢复了完整,他六个月的随访无痛功能。这些病例表明,对于先前的手术干预未能使锁骨中段骨折愈合的罕见情况,使用三皮质介入和加压钢板作为可行的选择。
    Several articles support the use of cancellous iliac crest bone grafting in the treatment of clavicle nonunion; however, there is very little literature on the use of tricortical iliac crest grafts in the setting of clavicle nonunion with bone loss. When it has been studied, tricortical grafting has been shown to produce radiologically confirmed union in the clavicle, leaving patients satisfied with the ultimate outcome. We present two cases of clavicle fracture nonunion successfully treated with tricortical interposition bone grafting. In the first case, a 45-year-old female presented with an atrophic left midshaft clavicle fracture nonunion with failed hardware that had undergone two previous attempts at fixation without achieving union. She was treated with a structural interposition iliac crest bone graft with plate fixation and regained full painless function of the arm with radiographic fracture union. In the second case, a 50-year-old male presented after a left midshaft clavicle fracture that had undergone acute stabilization, followed by revision for nonunion that was unsuccessful, resulting in persistent nonunion with bone loss. He was treated with a tricortical iliac crest bone graft and plate fixation. Cultures from the time of surgery did grow Staphylococcus epidermidis and Propionibacterium acnes, and he was treated with intravenous vancomycin for six weeks. The patient\'s clavicle went on to union and he regained full, painless function by his six-month follow-up visit. These cases demonstrate the use of tricortical interposition bone grafting with compression plating as a viable option for rare instances in which previous surgical intervention has failed to progress a midshaft clavicle fracture to union.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Clinical Trial
    目的:探讨全关节镜下自体髂骨植骨技术的疗效。此外,我们试图比较使用螺钉和纽扣固定的临床和影像学结果,复发性肩关节前不稳定患者。
    方法:在2015年至2019年之间,通过关节镜下放置的自体髂骨骨移植移植手术对134名患有持续性不稳定的肩膀进行了手术治疗。术前和术后的临床随访数据使用运动范围进行评估,和Walch-Duplay,美国肩肘协会(ASES),和Rowe得分。术前进行三维计算机断层扫描(CT)扫描的放射学评估,手术后立即,以及术后,3个月时,6个月,1年,在最后的后续阶段。移植物位置,愈合,从术后图像评估吸收。
    结果:本研究包括102例患者,这些患者接受关节镜下髂棘植骨手术,采用两颗螺钉固定(n=37;组1)和两颗纽扣固定(n=65;组2)。平均随访期为37个月。两组间临床评分无显著差异,肩部运动范围,移植物愈合,或CT扫描上的移植物位置(P>0.05)。在第1组中,一名患者在螺钉插入部位周围表现出机械刺激和持续疼痛,通过关节镜移除螺钉进行治疗。术后6个月平均骨吸收百分比分别为20.3%和11.2%,12个月时分别为32.4%和19.3%,分别在组1和组2中。两组比较差异有统计学意义(P<0.05).
    结论:在关节镜下治疗慢性骨性肩关节前不稳定的髂骨植骨手术中,按钮和螺钉固定技术后,均获得了出色的功能效果。此外,缝合按钮固定导致较少的移植物再吸收和缺乏硬件相关的并发症.
    To investigate the efficacy of all-arthroscopic glenoid bone augmentation surgery using the iliac crest autograft procedure. Furthermore, we sought to compare the clinical and radiographic outcomes of using screw versus button fixation, in patients with recurrent anterior shoulder instability.
    Between 2015 and 2019, 134 shoulders with persistent instability were surgically treated with an arthroscopically placed autologous iliac crest bone graft transfer procedure. Preoperative and postoperative clinical follow-up data were evaluated using the range of motion, and the Walch-Duplay, American Shoulder and Elbow Society, and Rowe scores. Radiologic assessment on 3-dimensional computed tomography scans was performed preoperatively, immediately after surgery, as well as postoperatively, at 3 months, 6 months, 1 year, and at the final follow-up stage. Graft positions, healing, and resorption were evaluated from postoperative images.
    This study included 102 patients who underwent arthroscopic iliac crest bone grafting procedure with 2 screws fixation (n = 37; group 1) and 2 button fixation (n = 65; group 2). The mean follow-up period was 37 months. There were no significant differences between groups in terms of clinical scores, shoulder motion range, graft healing, or graft positions on computed tomography scans (P>.05). In group 1, 1 patient showed mechanical irritation and persistent pain around the screw insertion site, being treated through the arthroscopic removal of the screws. The average postoperative bony resorption percentages were 20.3% and 11.2% at 6 months, and 32.4% and 19.3% at 12 months, in group 1 and group 2, respectively. A statistically significant difference was detected between the two groups (P<.05).
    In the arthroscopic iliac crest bone grafting procedure for the treatment of chronic osseous anterior shoulder instability, excellent functional results were obtained after both button fixation and screw fixation techniques. In addition, less graft resorption and no hardware-related complications were detected with suture button fixation technique.
    Level III, retrospective comparative therapeutic trial.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    介绍本研究的目的是评估使用非血管化髂棘移植物(ICGs)或血管化骨移植物(VBG)治疗长骨骨不连的结果。如股骨内侧髁皮质骨膜瓣(MFCFs)和腓骨瓣(FFs)。尽管一些研究已经检查了这些技术的结果,没有报告比较这些治疗方法并进行多因素分析.方法回顾性分析2007年4月至2018年11月接受长骨不愈合治疗的28例患者,包括9例女性和19例男性,平均年龄49.8岁(范围:16-72岁)。患者分为两组:A组17例患者接受VBG治疗(9例患者接受MFCF治疗,8例患者接受FF治疗),B组有11例患者接受ICG治疗。分析了以下参数:骨不连的射线照相图,创伤能量,骨折暴露,相关骨折,以前的手术,糖尿病,吸烟,年龄,和供体部位的发病率。结果VBG比非血管化移植物的治愈率(HR)提高了9.42倍。用VBG处理显示愈合时间减少25%。糖尿病使感染率增加了4.25倍。上肢感染率低70%。VBG患者的吸烟与HR下降75%有关,糖尿病与80%的下降有关。结论本研究报告VBG的成功率最高。与FFs相比,MFCFs似乎可以提供更好的临床和放射学结果,且供体部位发病率较低。
    Introduction  The purpose of the study was to evaluate the results of treatment of the nonunion of long bones using nonvascularized iliac crest grafts (ICGs) or vascularized bone grafts (VBGs), such as medial femoral condyle corticoperiosteal flaps (MFCFs) and fibula flaps (FFs). Although some studies have examined the results of these techniques, there are no reports that compare these treatments and perform a multifactorial analysis. Methods  The study retrospectively examined 28 patients comprising 9 women and 19 men with an average age of 49.8 years (range: 16-72 years) who were treated for nonunion of long bones between April 2007 and November 2018. The patients were divided into two cohorts: group A had 17 patients treated with VBGs (9 patients treated with MFCF and 8 with FF), while group B had 11 patients treated with ICG. The following parameters were analyzed: radiographic patterns of nonunion, trauma energy, fracture exposure, associated fractures, previous surgeries, diabetes, smoking, age, and donor-site morbidity. Results  VBGs improved the healing rate (HR) by 9.42 times more than the nonvascularized grafts. Treatment with VBGs showed a 25% decrease in healing time. Diabetes increased the infection rate by 4.25 times. Upper limbs showed 70% lower infection rate. Smoking among VBG patients was associated with a 75% decrease in the HR, and diabetes was associated with an 80% decrease. Conclusion  This study reports the highest success rates in VBGs. The MFCFs seem to allow better clinical and radiological outcomes with less donor-site morbidity than FFs.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号