Iliac crest bone graft

髂骨植骨
  • 文章类型: Journal Article
    后盂骨丢失(pGBL)通常与肩关节后不稳定有关。肩关节后路不稳定占肩关节病变的一小部分,和严重的骨丢失后不稳定在文献中还没有很好的定义。参与重复强调肩部后部稳定结构的活动的年轻患者群体更容易发生后部肩部不稳定。已经描述了多种手术选择,从孤立的囊膜修复到关节盂截骨术。在pGBL的情况下,单独的软组织修复可能是不充分的治疗,并且使患者处于高复发风险中。在pGBL的情况下,我们首选的后关节盂重建技术包括将游离的the骨移植物转移到天然关节盂上。移植物的轮廓适合骨缺损并固定以提供关节盂轨道的延伸。在这项研究中,我们回顾了pGBL在后部不稳定的背景下,并详细描述了我们的技术。需要进一步的长期研究来完善关节盂骨移植手术的适应症,并量化构成关键pGBL的因素。
    Posterior glenoid bone loss (pGBL) is frequently associated with posterior shoulder instability. Posterior glenohumeral instability accounts for a small percentage of shoulder pathologies, and critical bone loss in posterior instability has not been well defined in the literature. Younger patient populations who participate in activities that repetitively stress the posterior stabilizing structures of the shoulder are more prone to developing posterior shoulder instability. A variety of surgical options have been described, ranging from isolated capsulolabral repair to glenoid osteotomy. Soft-tissue repair alone may be an inadequate treatment in cases of pGBL and places patients at a high risk of recurrence. Our preferred technique for posterior glenoid reconstruction in cases of pGBL involves the transfer of a free iliac crest bone graft onto the native glenoid. The graft is contoured to fit the osseous defect and secured to provide an extension of the glenoid track. In this study, we review pGBL in the setting of posterior instability and describe our technique in detail. Further long-term studies are needed to refine the indications for glenoid bone graft procedures and quantify what constitutes a critical pGBL.
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    文章类型: Randomized Controlled Trial
    BACKGROUND: spinal fusion is used to treat, among other pathologies, the degenerative intervertebral disc disease. Autologous iliac crest bone grafting is the golden standard treatment for increasing the rate of fusion; however, it isn\'t free of complications.
    OBJECTIVE: to investigate whether patients who have posterior iliac crest graft harvesting and are blinded to the donor site, can identify from which side the graft was harvested, and whether the intensity of this pain is related to the amount of graft obtained.
    METHODS: prospective, experimental, randomized and comparative, single-blind study. Adult patients who underwent primary instrumented open posterolateral lumbar fusion with autologous iliac crest bone graft between July 2019 and April 2020 were included. Patients were divided into two randomized groups. The amount of graft to be harvested was according to surgical needs. The patients were asked about pain according to the visual analogue scale in the first, third and sixth months after surgery, always requesting that the most painful side be identified.
    RESULTS: a total of 44 patients (n = 23 right crest, n = 21 left crest) were analyzed. Most patients were unable to identify the side from which the bone graft was harvested, with a statistically significant difference (p-value 0.0001).
    CONCLUSIONS: iliac crest bone graft harvesting is an effective and safe procedure that improves the rates of fusion without increasing the patient\'s morbidity.
    UNASSIGNED: la fusión espinal es utilizada para tratar, entre otras patologías, las enfermedades degenerativas discales. El injerto óseo autólogo de cresta ilíaca es el estándar de oro para aumentar las probabilidades de fusión; sin embargo, no está exento de complicaciones.
    OBJECTIVE: investigar si los pacientes a los que se les recolecta injerto de cresta ilíaca posterior y son cegados al lado del sitio donante, pueden identificar de qué lado se tomó dicho injerto y si la intensidad de este dolor está en relación con la cantidad de injerto obtenido.
    UNASSIGNED: trabajo prospectivo, experimental, aleatorizado y comparativo, simple ciego. Se incluyeron pacientes adultos operados entre Julio de 2019 hasta Abril de 2020, a los cuales se les realizó una cirugía primaria de artrodesis lumbar posterolateral abierta instrumentada, con colocación de injerto óseo autólogo de cresta ilíaca. Se dividió a los pacientes en dos grupos aleatorizados. La cantidad de injerto a recolectar fue de acuerdo a las necesidades quirúrgicas. Se interrogó por el dolor según escala visual analógica al primer, tercer y sexto mes de la cirugía, siempre solicitando que se identifique el lado más doloroso.
    RESULTS: se analizaron 44 pacientes (n = 23 cresta derecha, n = 21 cresta izquierda). La mayoría de los pacientes no lograron identificar el lado del cual se obtuvo el injerto óseo, con una diferencia estadística ampliamente significativa (p = 0.0001).
    UNASSIGNED: la obtención de injerto óseo de cresta ilíaca es un procedimiento efectivo y seguro, que mejora las probabilidades de fusión sin aumentar la morbilidad del paciente.
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  • 文章类型: Journal Article
    目的:介绍采用大骨骨移植治疗严重胫骨骨缺损的方法和经验。
    方法:从2020年1月至2022年1月,对20例严重胫骨骨缺损患者(10名男性和10名女性)进行了骨移植。骨缺损的平均长度为13.59±3.41。收获双侧髂骨移植物,包括髂棘的内外板。皮质骨螺钉用于将两个髂骨块整合成一个复合体。锁定板用于固定移植物-宿主复合物,必要时辅以重建板,以增加稳定性。在随访时通过X线照片上的皮质骨融合评估骨愈合,通过VAS评分评估髂痛,通过ODI评分评估下肢功能。并发症也被考虑在内。
    结果:平均随访时间为27.4±5.6(范围24-33个月),平均VAS评分为8.8±1.9,平均ODI评分为11.1±1.8,植骨区皮质骨融合数为3.5±0.5。在所有the骨移植宿主部位的病例中均获得了令人满意的融合。没有骨不连,所有病例均出现移位或骨折。没有观察到需要二次手术的感染和骨吸收。一名患者有大脚趾背屈无力。在2例患者中观察到了足背的感觉减退。3例患者出现踝关节僵硬和水肿。通过物理治疗和康复训练,并发症得到明显改善。
    结论:对于严重大小的胫骨骨缺损,治疗方法多种多样。在本文中,我们通过使用大的髂骨移植治疗骨缺损,获得了满意的效果。这种方法不仅可以恢复胫骨的完整性,而且内固定也获得了良好的稳定性,和操作技能更容易被外科医生接受。因此,它为临床医生提供了一种替代的手术方法。
    OBJECTIVE: To introduce the method and experience of treating critical-sized tibial bone defect by taking large iliac crest bone graft.
    METHODS: From January 2020 to January 2022, iliac crest bone grafting was performed in 20 patients (10 men and 10 women) with critical-sized tibial bone defect. The mean length of bone defect was 13.59 ± 3.41. Bilateral iliac crest grafts were harvested, including the inner and outer plates of the iliac crest and iliac spine. The cortical bone screw was used to integrate two iliac bone blocks into one complex. Locking plate was used to fix the graft-host complex, supplemented with reconstruction plate to increase stability when necessary. Bone healing was evaluated by cortical bone fusion on radiographs at follow-up, iliac pain was assessed by VAS score, and lower limb function was assessed by ODI score. Complications were also taken into consideration.
    RESULTS: The average follow-up time was 27.4 ± 5.6 (Range 24-33 months), the mean VAS score was 8.8 ± 1.9, the mean ODI score was 11.1 ± 1.8, and the number of cortical bone fusion in the bone graft area was 3.5 ± 0.5. Satisfactory fusion was obtained in all cases of iliac bone transplant-host site. No nonunion, shift or fracture was found in all cases. No infection and bone resorption were observed that need secondary surgery. One patient had dorsiflexion weakness of the great toe. Hypoesthesia of the dorsal foot was observed in 2 patients. Ankle stiffness and edema occurred in 3 patients. Complications were significantly improved by physical therapy and rehabilitation training.
    CONCLUSIONS: For the cases of critical-sized tibial bone defect, the treatment methods are various. In this paper, we have obtained satisfactory results by using large iliac bone graft to treat bone defect. This approach can not only restore the integrity of the tibia, but also obtain good stability with internal fixation, and operation skills are more acceptable for surgeons. Therefore, it provides an alternative surgical method for clinicians.
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  • 文章类型: Case Reports
    背景:石骨病包括一组罕见的遗传性疾病,并导致骨结构异常。由于破骨细胞无功能或缺乏,因此骨重塑受到极大抑制。这种情况导致骨骼过度生长,骨髓消失,导致再生障碍性贫血;颅骨神经通道阻塞会导致失明和听力损害。在大多数情况下,骨硬化导致口腔并发症,如牙齿变形,低矿化,牙齿萌出延迟或缺失。唯一的治愈性治疗是造血干细胞移植(HSCT)。儿童期和青春期口腔并发症的主要治疗包括通过预防性治疗来保护萌出的牙齿免受龋齿疾病的侵害,所述预防性治疗旨在通过一生中频繁的定期牙科就诊来实现最佳的口腔卫生。许多患有骨硬化症的患者需要主要的口腔康复来治疗该疾病的并发症。HSCT的改善结果增加了牙科专业人员遇到石骨症患者的可能性。
    方法:在本案例报告中,我们表明,患有严重口腔并发症的石骨症患者,如果在早期接受石骨症治疗,可以成功治疗。这个男孩在儿科接受了牙齿护理,并定期举行多学科会议,以制定未来的治疗计划。15岁时,他被转介康复。初步评估显示牙槽骨没有进一步生长。康复是逐步进行的,拔除畸形和错位的牙齿。最初,患者接受了可摘局部义齿,然后重建了牙槽突的宽度,钛植入物,临时固定桥,最后是螺丝保留的钛陶瓷桥,带有上下颚的钛框架。
    结论:负荷后的三年随访表明,由于频繁的专业口腔卫生护理,边缘骨水平稳定,口腔卫生最佳。患者没有表现出来自颞下颌关节的症状迹象,并且已经适应了新的颌骨关系,没有任何功能或语音问题。
    Osteopetrosis comprises a group of inherited disorders that are rare and result in abnormal bone structure. Bone remodeling is extremely inhibited because osteoclasts are nonfunctional or lacking. This condition causes overgrowth of bone with disappearance of the bone marrow, leading to aplastic anemia; obstruction of nerve passages in the skull leads to blindness and often hearing impairment. In most cases, osteopetrosis results in oral complications such as tooth deformation, hypomineralization, and delayed or absent tooth eruption. The only curative treatment is hematopoietic stem cell transplantation (HSCT). The main treatment of the oral complications during childhood and adolescence consists in protecting the erupted teeth against caries disease through prophylactic treatment aimed at optimal oral hygiene through frequent regular dental visits throughout life. Many patients with osteopetrosis require major oral rehabilitation to treat complications of the disease. Improved results of HSCT increase the likelihood that dental professionals will encounter patients with osteopetrosis.
    In this case report, we show that individuals with osteopetrosis who have severe oral complications can be treated successfully if they are treated for osteopetrosis at an early age. The boy had his dental care in pedodontics, and regular multidisciplinary meetings were held for future treatment planning. At the age of 15, he was then referred for rehabilitation. The initial evaluations revealed no further growth in the alveolar bone. The rehabilitation was done stepwise, with extraction of malformed and malpositioned teeth. Initially, the patient received a removable partial denture followed by reconstruction of the width of the alveolar process, titanium implants, temporary fixed bridges, and finally screw-retained titanium-ceramic bridges with titanium frames for the upper and lower jaws.
    The three-year follow-up after loading indicated a stable marginal bone level and optimal oral hygiene as a result of frequent professional oral hygiene care. The patient showed no signs of symptoms from the temporomandibular joint and has adapted to the new jaw relation without any functional or phonetical issues.
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  • 文章类型: Journal Article
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  • 文章类型: Clinical Trial
    目的:探讨全关节镜下自体髂骨植骨技术的疗效。此外,我们试图比较使用螺钉和纽扣固定的临床和影像学结果,复发性肩关节前不稳定患者。
    方法:在2015年至2019年之间,通过关节镜下放置的自体髂骨骨移植移植手术对134名患有持续性不稳定的肩膀进行了手术治疗。术前和术后的临床随访数据使用运动范围进行评估,和Walch-Duplay,美国肩肘协会(ASES),和Rowe得分。术前进行三维计算机断层扫描(CT)扫描的放射学评估,手术后立即,以及术后,3个月时,6个月,1年,在最后的后续阶段。移植物位置,愈合,从术后图像评估吸收。
    结果:本研究包括102例患者,这些患者接受关节镜下髂棘植骨手术,采用两颗螺钉固定(n=37;组1)和两颗纽扣固定(n=65;组2)。平均随访期为37个月。两组间临床评分无显著差异,肩部运动范围,移植物愈合,或CT扫描上的移植物位置(P>0.05)。在第1组中,一名患者在螺钉插入部位周围表现出机械刺激和持续疼痛,通过关节镜移除螺钉进行治疗。术后6个月平均骨吸收百分比分别为20.3%和11.2%,12个月时分别为32.4%和19.3%,分别在组1和组2中。两组比较差异有统计学意义(P<0.05).
    结论:在关节镜下治疗慢性骨性肩关节前不稳定的髂骨植骨手术中,按钮和螺钉固定技术后,均获得了出色的功能效果。此外,缝合按钮固定导致较少的移植物再吸收和缺乏硬件相关的并发症.
    To investigate the efficacy of all-arthroscopic glenoid bone augmentation surgery using the iliac crest autograft procedure. Furthermore, we sought to compare the clinical and radiographic outcomes of using screw versus button fixation, in patients with recurrent anterior shoulder instability.
    Between 2015 and 2019, 134 shoulders with persistent instability were surgically treated with an arthroscopically placed autologous iliac crest bone graft transfer procedure. Preoperative and postoperative clinical follow-up data were evaluated using the range of motion, and the Walch-Duplay, American Shoulder and Elbow Society, and Rowe scores. Radiologic assessment on 3-dimensional computed tomography scans was performed preoperatively, immediately after surgery, as well as postoperatively, at 3 months, 6 months, 1 year, and at the final follow-up stage. Graft positions, healing, and resorption were evaluated from postoperative images.
    This study included 102 patients who underwent arthroscopic iliac crest bone grafting procedure with 2 screws fixation (n = 37; group 1) and 2 button fixation (n = 65; group 2). The mean follow-up period was 37 months. There were no significant differences between groups in terms of clinical scores, shoulder motion range, graft healing, or graft positions on computed tomography scans (P>.05). In group 1, 1 patient showed mechanical irritation and persistent pain around the screw insertion site, being treated through the arthroscopic removal of the screws. The average postoperative bony resorption percentages were 20.3% and 11.2% at 6 months, and 32.4% and 19.3% at 12 months, in group 1 and group 2, respectively. A statistically significant difference was detected between the two groups (P<.05).
    In the arthroscopic iliac crest bone grafting procedure for the treatment of chronic osseous anterior shoulder instability, excellent functional results were obtained after both button fixation and screw fixation techniques. In addition, less graft resorption and no hardware-related complications were detected with suture button fixation technique.
    Level III, retrospective comparative therapeutic trial.
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  • 文章类型: Journal Article
    介绍本研究的目的是评估使用非血管化髂棘移植物(ICGs)或血管化骨移植物(VBG)治疗长骨骨不连的结果。如股骨内侧髁皮质骨膜瓣(MFCFs)和腓骨瓣(FFs)。尽管一些研究已经检查了这些技术的结果,没有报告比较这些治疗方法并进行多因素分析.方法回顾性分析2007年4月至2018年11月接受长骨不愈合治疗的28例患者,包括9例女性和19例男性,平均年龄49.8岁(范围:16-72岁)。患者分为两组:A组17例患者接受VBG治疗(9例患者接受MFCF治疗,8例患者接受FF治疗),B组有11例患者接受ICG治疗。分析了以下参数:骨不连的射线照相图,创伤能量,骨折暴露,相关骨折,以前的手术,糖尿病,吸烟,年龄,和供体部位的发病率。结果VBG比非血管化移植物的治愈率(HR)提高了9.42倍。用VBG处理显示愈合时间减少25%。糖尿病使感染率增加了4.25倍。上肢感染率低70%。VBG患者的吸烟与HR下降75%有关,糖尿病与80%的下降有关。结论本研究报告VBG的成功率最高。与FFs相比,MFCFs似乎可以提供更好的临床和放射学结果,且供体部位发病率较低。
    Introduction  The purpose of the study was to evaluate the results of treatment of the nonunion of long bones using nonvascularized iliac crest grafts (ICGs) or vascularized bone grafts (VBGs), such as medial femoral condyle corticoperiosteal flaps (MFCFs) and fibula flaps (FFs). Although some studies have examined the results of these techniques, there are no reports that compare these treatments and perform a multifactorial analysis. Methods  The study retrospectively examined 28 patients comprising 9 women and 19 men with an average age of 49.8 years (range: 16-72 years) who were treated for nonunion of long bones between April 2007 and November 2018. The patients were divided into two cohorts: group A had 17 patients treated with VBGs (9 patients treated with MFCF and 8 with FF), while group B had 11 patients treated with ICG. The following parameters were analyzed: radiographic patterns of nonunion, trauma energy, fracture exposure, associated fractures, previous surgeries, diabetes, smoking, age, and donor-site morbidity. Results  VBGs improved the healing rate (HR) by 9.42 times more than the nonvascularized grafts. Treatment with VBGs showed a 25% decrease in healing time. Diabetes increased the infection rate by 4.25 times. Upper limbs showed 70% lower infection rate. Smoking among VBG patients was associated with a 75% decrease in the HR, and diabetes was associated with an 80% decrease. Conclusion  This study reports the highest success rates in VBGs. The MFCFs seem to allow better clinical and radiological outcomes with less donor-site morbidity than FFs.
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  • 文章类型: Journal Article
    骨丢失已被确定为软组织修复后复发性肩关节脱位或失败的风险因素。尽管“严重”骨丢失的范围尚未确定,关节盂和肱骨骨缺损不应被视为独立的问题,但肩关节运动过程中它们之间的相互作用应按照关节盂轨道概念的建议进行评估。现在,关节盂轨道的概念已被广泛接受,并被认为对于做出有关手术的决定至关重要。软组织程序通常适用于轨道上Hill-Sachs病变的患者,但在轨道外病变中效果不佳。在这种情况下,应执行其他程序。已经描述了不同的手术选择来解决偏离轨道的Hill-Sachs病变,最常见的是remplissage,Latarjet或游离骨块程序。喙突移植物和游离骨移植物通过延长关节盂轨道将偏离轨道的Hill-Sachs病变转变为轨道上的病变,而remplissage填充肱骨病变,使其不接合。在Hill-Sachs病变的背景下,很少或没有关节盂骨丢失,remplissage显示出令人满意的结果,并发症和复发率低。据报道,当处理孤立的Hill-Sachs或双极病变时,关节盂骨移植取得了良好的结果。分析Latarjet和Eden-Hybinette程序的研究表明,这两种程序在治疗前肱骨不稳方面都是安全有效的。应注意那些无法使用孤立的Latarjet修复的大骨缺损患者,这些患者可以通过Eden-Hybinnete或在Latarjet程序中添加remplissage更好地解决。
    Bone loss has been identified as a risk factor for recurrent shoulder dislocations or failure after soft tissue repair. Although the range for \"critical\" bone loss is yet to be determined, glenoid and humeral bone defects should not be regarded as independent problems, but the interaction between them during shoulder motion should be evaluated as suggested by the glenoid track concept. The glenoid track concept is now widely accepted and considered essential for making decisions about surgery. Soft-tissue procedures usually work well in patients with on-track Hill-Sachs lesions but in off-track lesions do not. In this situation additional procedures should be performed.Different surgical options have been described to address off-track Hill-Sachs lesions, most commonly remplissage, Latarjet or free bone block procedures. Coracoid graft and free bone grafts convert the off-track Hill-Sachs lesion into on-track by lengthening the glenoid-track, whereas remplissage fill-in the humeral lesion so that it does not engage. In the setting of a Hill-Sachs lesion with little or no glenoid bone loss, remplissage has demonstrated satisfactory outcomes with a low complications and recurrence rate. Favorable results have been reported with glenoid bone grafting when managing isolated Hill-Sachs or bipolar lesions. Studies analyzing Latarjet and Eden-Hybinette procedures show that both procedures are safe and effective in the management of anterior glenohumeral instability. Attention should be paid to those patients with large bone defects not amenable to be restored with an isolated Latarjet that may be better addressed with an Eden-Hybinnete or adding a remplissage to the Latarjet procedure.
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  • 文章类型: Randomized Controlled Trial
    在这个临床试验中,患者随机接受带蒂血管化骨移植,基于1,2-室间视网膜上动脉,或者非血管化髂嵴移植物.用K线进行固定。定期使用CT扫描评估工会和工会时间。23名患者接受了血管化移植,22人接受了非血管化移植。38例患者可用于工会评估,23例用于临床测量。工会发生率没有显着差异,工会的时间,并发症的发生率,患者报告的结果评分,或治疗组之间的最后随访时的手腕活动能力和握力。吸烟者实现工会的可能性降低了60%,独立于移植物类型。控制吸烟时,接受血管化移植的患者实现愈合的可能性高出72%.鉴于我们的样本量很小,结果应谨慎解释。
    In this clinical trial, patients were randomized to receive a pedicled vascularized bone graft, based on the 1,2-intercompartmental supraretinacular artery, or a non-vascularized iliac crest graft. Fixation was done with K-wires. Union and time to union were assessed using CT scans at regular intervals. Twenty-three patients received a vascularized graft, and 22 received a non-vascularized graft. Thirty-eight patients were available for union assessment and 23 for clinical measurements. There were no significant differences in union incidence, time to union, incidence of complications, patient-reported outcome scores, or wrist mobility and grip strength at final follow-up between the treatment groups. Smokers were 60% less likely to achieve union, independent of graft type. When controlling for smoking, patients receiving a vascularized graft were 72% more likely to achieve union. Given our small sample size, results should be interpreted with caution.Level of evidence: I.
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  • 文章类型: Meta-Analysis
    目的:对自体血小板浓缩物(APC)联合髂嵴植骨(ICBG)重建继发性牙槽突裂的现有证据进行综述。
    方法:系统搜索电子数据库,直到2022年11月。纳入了临床试验,比较了使用ICBG和APC进行二次牙槽骨移植(SABG)的患者与仅使用ICBG的患者的三维放射学结果以及术后6个月评估的放射学结果。两位作者进行了研究选择和偏倚风险评估。使用随机效应模型进行荟萃分析,以确定发生伤口裂开的风险比(RR)和新形成的骨百分比的95%置信区间(CI)的平均差(MD)。
    结果:纳入了9项研究(7项RCT和2项CCT),偏倚风险从低到高。在6个月的随访中,研究组显示新形成骨百分比的结果不显著(MD=6.49;95%CI:-0.97,13.94;p=.09;χ2=0.01;I2=71%)。此外,研究组发生伤口裂开的总体风险较低(RR=0.34;95%CI:0.15,0.78;p=.01;χ2=0.67;I2=0%).
    结论:目前,没有足够的证据支持在二次牙槽骨移植后辅助使用ICBG辅助APC增强骨再生.然而,结合ICBG和APC可能有利于降低伤口裂开的风险。
    OBJECTIVE: To review the existing evidence on the adjuvant use of autologous platelet concentrates (APCs) with iliac crest bone graft (ICBG) in the reconstruction of the secondary alveolar cleft.
    METHODS: Electronic databases were searched systematically until November 2022. Clinical trials comparing the three-dimensional radiological outcomes of patients who underwent secondary alveolar bone grafting (SABG) with ICBG and APCs to those with ICBG alone and the radiological outcomes assessed 6 months after surgery were included. Two authors performed the study selection and the assessment of the risk of bias. Meta-analysis was performed using the random-effects model to determine the risk ratio (RR) for developing wound dehiscence and the mean difference (MD) with a 95% confidence interval (CI) for the percentage of newly formed bone.
    RESULTS: Nine studies (seven RCT and two CCT) were included with a low to high risk of bias. At the 6-month follow-up, the study group revealed insignificant results regarding the percentage of newly formed bone (MD = 6.49; 95% CI: -0.97, 13.94; p = .09; χ2  = 0.01; I2  = 71%). In addition, the overall risk of developing wound dehiscence was lower in the study group (RR = 0.34; 95% CI: 0.15, 0.78; p = .01; χ2  = 0.67; I2  = 0%).
    CONCLUSIONS: Currently, there is insufficient evidence to support the adjuvant use of APCs with ICBG on enhanced bone regeneration following secondary alveolar bone grafting. However, combining ICBG and APCs might be beneficial in reducing the risk of developing wound dehiscence.
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