■HypermobileEhlers-Danlos综合征(hEDS)和高移动性频谱障碍(HSD)是尚未研究的疾病,其特征是标志性的高移动性和慢性疼痛。疾病表现导致严重残疾。了解残疾的预测因素,超越疼痛严重程度的单变量结构,是必要的定制治疗。因此,本研究检查了恐惧-回避模型[FAM]对hEDS/HSD残疾的影响。对跌倒的恐惧被列为影响残疾的一种新的避免恐惧因素。
■共有168名hEDS/HSD患者回答了有关FAM结构的横断面在线调查,害怕跌倒,残疾,和临床人口统计学因素。分层回归分析用于评估FAM构建和对跌倒的恐惧是否显着预测残疾,超过疼痛的严重程度和年龄。
■痛苦的灾难,焦虑,对跌倒的恐惧贡献了重要的独特预测关系,高于年龄和平均疼痛严重程度。疼痛严重程度和对跌倒的恐惧是残疾的最强独特预测因素。
■这是第一项评估FAM结构之间关系的研究,疼痛严重程度,和hEDS/HSD的残疾,并引入了对跌倒的恐惧作为该人群特有的新颖的避免恐惧因素。未来的研究应将这些发现应用于个性化干预措施,以改善hEDS/HSD的残疾。
残疾在高移动性Ehlers-Danlos综合征和高移动性频谱障碍中很重要,并且可以通过焦虑的心理社会因素来预测,痛苦的灾难,害怕跌倒。我们的发现表明,改善超移动Ehlers-Danlos综合征和高移动频谱障碍的残疾需要考虑物理因素,如疼痛严重程度,连同社会心理因素,后者可以通过个性化干预计划进行更改。对跌倒的恐惧是一种新颖的避免恐惧的结构,应在未来的研究和临床环境中加以考虑,以增加这种经常跌倒的人群的功能。
UNASSIGNED: Hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorders (HSD) are understudied conditions characterized by hallmark hypermobility and chronic pain. Disease manifestations lead to significant disability. Understanding predictors of disability, over and above the univariate construct of pain severity, is necessary to tailor treatment. Thus, the current study examined the impact of the Fear-Avoidance Model [FAM] on disability in hEDS/HSD. Fear of falling was included as a novel fear-avoidance factor impacting disability.
UNASSIGNED: A total of 168 individuals with hEDS/HSD answered a cross-sectional online survey regarding FAM constructs, fear of falling, disability, and clinical-demographic factors. A hierarchical regression analysis was used to assess whether FAM constructs and fear of falling significantly predicted disability, over and above pain severity and age.
UNASSIGNED: Pain catastrophizing, anxiety, and fear of falling contributed significant unique predictive relations, above age and average pain severity. Pain severity and fear of falling were the strongest unique predictors of disability.
UNASSIGNED: This is the first study to assess the relations among FAM constructs, pain severity, and disability in hEDS/HSD, and introduces fear of falling as a novel fear-avoidance factor specific to this population. Future research should apply these findings towards individualized interventions to improve disability in hEDS/HSD.
Disability is significant in hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders, and may be predicted by psychosocial factors of anxiety, pain catastrophizing, and fear of falling.Our findings suggest that improving disability in hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders involves the consideration of physical factors, such as pain severity, along with psychosocial factors, the latter of which are amenable to change through individualized intervention plans.Fear of falling is a novel fear-avoidance construct that should be considered in future research and clinical settings to increase functionality in this frequently falling population.