■医院获得性肺炎是导致疾病反复发作的重要原因之一,疾病进展,甚至在住院期间死亡。精神分裂症患者有其疾病的特殊性,同时,医院获得性肺炎的发生在精神分裂症患者中更为常见,因为他们长期住在封闭病房,伴随着各种因素,如年龄,性别,和营养状况。
■PubMed,WebofScience,科克伦图书馆,中国国家知识基础设施(CNKI),检索中国生物医学文献数据库(CBM)数据库,时间范围为2024年2月,收集精神分裂症患者医院获得性肺炎影响因素的研究.两名研究人员独立筛选了文献,提取的数据,并分析了它们。
■共5篇论文,包括85246名患者,这表明苯二氮卓类药物(尤其是使用氯氮平),抗精神病药物的组合,情绪稳定剂,改良电休克疗法(MECT),住院时间,潜在的疾病,高血糖症,流涎/吞咽困难是精神分裂症患者医院获得性肺炎的重要危险因素,和那个高龄,吸烟和饮酒年龄较大,吸烟和饮酒习惯,营养不良,和基础疾病也是医院获得性肺炎的危险因素。
精神分裂症患者发生医院获得性肺炎的风险更高,因此,识别与医院获得性肺炎相关的危险因素并在住院期间对其进行全面和及时的评估有助于早期干预措施的发展,这对于改善精神分裂症患者的预后至关重要。
UNASSIGNED: Hospital-acquired pneumonia is one of the most important causes of recurrent illness, disease progression, and even death during hospitalization. Patients with schizophrenia have the special characteristics of their disease, and at the same time, the occurrence of hospital-acquired pneumonia is more common among patients with schizophrenia due to the prolonged stay in closed wards, accompanied by various factors such as age, gender, and nutritional status.
UNASSIGNED: The PubMed, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), and China Biomedical Literature Database (CBM) databases were searched with a timeframe of build to February 2024 to collect studies on factors influencing hospital-acquired pneumonia in patients with schizophrenia. Two researchers independently screened the literature, extracted data, and analyzed them.
UNASSIGNED: A total of 5 papers including 85246 patients were included in the literature, which suggested that benzodiazepines (especially the use of clozapine), combination of antipsychotics, mood stabilizers, modified electroconvulsive therapy (MECT), duration of hospitalization, underlying diseases, hyperglycemia, and salivation/dysphagia were important risk factors for hospital-acquired pneumonia in schizophrenia patients, and that advanced age, smoking and alcohol drinking Older age, smoking and drinking habits, malnutrition, and underlying diseases are also risk factors for hospital-acquired pneumonia.
UNASSIGNED: Patients with schizophrenia are at a higher risk of developing hospital-acquired pneumonia, so identifying the risk factors associated with hospital-acquired pneumonia and evaluating them comprehensively and promptly during hospitalization facilitates the development of early interventions, which are essential for improving the prognosis of patients with schizophrenia.