Abstract：
UNASSIGNED: Hospital-acquired pneumonia (HAP) is the most common hospital-acquired infection (HAI). HAP is associated with a high burden of morbidity and mortality, but the diagnosis is difficult to establish and the incidence uncertain.
UNASSIGNED: Patients aged ≥ 18 years hospitalised with radiologically verified non-ventilator hospital acquired pneumonia (NV-HAP) during 2018 were retrospectively identified at Drammen Hospital, a Norwegian general hospital. Infectious Diseases Society of America and the American Thoracic Society\'s definition of HAP was used.
UNASSIGNED: In total 119 cases of NV-HAP were identified among 27,701 admissions. The incidence was 4.3 per 1000 admissions and 1.2 per 1000 patient-days. The median age was 74 years, 63% were male and median Charlson comorbidity index was 5. Coronary heart disease (42%) was the most common comorbidity. Median length of stay was 17.2 days. A blood culture was obtained in 53.8% of patients, while samples from lower airways were seldom obtained (10.9%). In-hospital mortality was 21%, accumulated 30-day mortality was 27.7% and accumulated 1-year mortality was 39.5%. Thirty-day readmission rate among survivors was 39.4%.
UNASSIGNED: NV-HAP was present in approximately 1 in 250 hospitalisations, most had multiple comorbidities, and 1 in 5 died in hospital. Although thorough microbiological sampling is recommended when NV-HAP is suspected, our data indicate that airway sampling is infrequent in clinical practice. Our findings underscore the need to develop microbiological diagnostic strategies to achieve targeted antimicrobial treatment that may improve patient outcomes and reduce broad-spectrum antibiotic usage.
UNASSIGNED: Patients aged ≥ 18 years hospitalised with radiologically verified non-ventilator hospital acquired pneumonia (NV-HAP) during 2018 were retrospectively identified at Drammen Hospital, a Norwegian general hospital. Infectious Diseases Society of America and the American Thoracic Society\'s definition of HAP was used.
UNASSIGNED: In total 119 cases of NV-HAP were identified among 27,701 admissions. The incidence was 4.3 per 1000 admissions and 1.2 per 1000 patient-days. The median age was 74 years, 63% were male and median Charlson comorbidity index was 5. Coronary heart disease (42%) was the most common comorbidity. Median length of stay was 17.2 days. A blood culture was obtained in 53.8% of patients, while samples from lower airways were seldom obtained (10.9%). In-hospital mortality was 21%, accumulated 30-day mortality was 27.7% and accumulated 1-year mortality was 39.5%. Thirty-day readmission rate among survivors was 39.4%.
UNASSIGNED: NV-HAP was present in approximately 1 in 250 hospitalisations, most had multiple comorbidities, and 1 in 5 died in hospital. Although thorough microbiological sampling is recommended when NV-HAP is suspected, our data indicate that airway sampling is infrequent in clinical practice. Our findings underscore the need to develop microbiological diagnostic strategies to achieve targeted antimicrobial treatment that may improve patient outcomes and reduce broad-spectrum antibiotic usage.
摘要：
■医院获得性肺炎（HAP）是最常见的医院获得性感染（HAI）。HAP与高发病率和死亡率相关，但是诊断很难确定，发病率也不确定。
■2018年期间因放射学证实的非呼吸机医院获得性肺炎（NV-HAP）住院的年龄≥18岁的患者在Drammen医院进行了回顾性鉴定。挪威综合医院。使用美国传染病学会和美国胸科学会对HAP的定义。
■在27,701例入院中，共发现119例NV-HAP。发病率为4.3/1000入院和1.2/1000患者天。中位年龄74岁,63%为男性，中位Charlson合并症指数为5。冠心病（42％）是最常见的合并症。平均逗留时间为17.2天。53.8%的患者进行了血培养,而来自下气道的样本很少(10.9%)。住院死亡率为21%，累积30日死亡率为27.7%,累积1年死亡率为39.5%.幸存者30天再入院率为39.4%。
■NV-HAP在250例住院患者中约有1例出现，大多数有多种合并症，五分之一的人在医院死亡。尽管当怀疑NV-HAP时，建议进行彻底的微生物采样，我们的数据表明,在临床实践中,气道采样很少见.我们的发现强调了开发微生物学诊断策略以实现靶向抗菌治疗的必要性，这可能会改善患者的预后并减少广谱抗生素的使用。
■2018年期间因放射学证实的非呼吸机医院获得性肺炎（NV-HAP）住院的年龄≥18岁的患者在Drammen医院进行了回顾性鉴定。挪威综合医院。使用美国传染病学会和美国胸科学会对HAP的定义。
■在27,701例入院中，共发现119例NV-HAP。发病率为4.3/1000入院和1.2/1000患者天。中位年龄74岁,63%为男性，中位Charlson合并症指数为5。冠心病（42％）是最常见的合并症。平均逗留时间为17.2天。53.8%的患者进行了血培养,而来自下气道的样本很少(10.9%)。住院死亡率为21%，累积30日死亡率为27.7%,累积1年死亡率为39.5%.幸存者30天再入院率为39.4%。
■NV-HAP在250例住院患者中约有1例出现，大多数有多种合并症，五分之一的人在医院死亡。尽管当怀疑NV-HAP时，建议进行彻底的微生物采样，我们的数据表明,在临床实践中,气道采样很少见.我们的发现强调了开发微生物学诊断策略以实现靶向抗菌治疗的必要性，这可能会改善患者的预后并减少广谱抗生素的使用。
