■无家可归的人患有疫苗可预防的传染病。此外,他们特别容易受到不良感染结果的影响,无法进入医疗保健系统。关于麻疹血清阳性率的数据,腮腺炎,风疹,这个队列中的水痘不见了。
■麻疹的血清阳性率,腮腺炎,风疹,水痘是在德国无家可归的人群中确定的。使用多变量逻辑回归分析确定缺乏免疫保护的预测因子。
■德国的无家可归者(n=611)的麻疹血清阳性率为88.5%(95%CI:85.8-91.0),腮腺炎占83.8%(95%CI:80.6-86.6),风疹占86.1%(95%CI:83.1-88.7),水痘占95.7%(95%CI93.8-97.2)。麻疹血清价值从1965年出生的个体下降到1993年出生的个体,血清价值与1980年以后出生的个体的95%阈值不相容。对于腮腺炎,从1950年出生的个体到1984年出生的个体,血清价值下降。这里,对于1975年以后出生的个体,血清价值与92%的阈值不符。麻疹的血清学性,腮腺炎和风疹与年龄有关,但与性别或原籍国无关。
■在这个无家可归的群体中,对麻疹和腮腺炎的群体免疫没有实现,同时对风疹和水痘有足够的免疫保护。年轻人的免疫保护率下降,需要开展免疫运动,也针对无家可归的人等边缘化群体。鉴于1980年后出生的麻疹个体没有达到群体免疫阈值,1975年之后的腮腺炎,疫苗接种运动应优先考虑这些年龄组的个人。
UNASSIGNED: Homeless individuals suffer a high burden of vaccine-preventable infectious diseases. Moreover, they are particularly susceptible to adverse infection outcomes with limited access to the health care system. Data on the seroprevalence of measles, mumps, rubella, and varicella within this cohort are missing.
UNASSIGNED: The seroprevalence of measles, mumps, rubella, and varicella was determined within the
homeless population in Germany. Predictors of lacking immune protection were determined using multivariable logistic regression analysis.
UNASSIGNED: Homeless individuals in Germany (n = 611) showed a seroprevalence of 88.5% (95% CI: 85.8-91.0) for measles, 83.8% (95% CI: 80.6-86.6) for mumps, 86.1% (95% CI: 83.1-88.7) for rubella, and 95.7% (95% CI 93.8-97.2) for varicella. Measles seroprevalences declined from individuals born in 1965 to individuals born in 1993, with seroprevalences not compatible with a 95% threshold in individuals born after 1980. For mumps, seroprevalences declined from individuals born in 1950 to individuals born in 1984. Here, seroprevalences were not compatible with a 92% threshold for individuals born after 1975. Seronegativity for measles, mumps and rubella was associated with age but not with gender or country of origin.
UNASSIGNED: Herd immunity for measles and mumps is not achieved in this
homeless cohort, while there was sufficient immune protection for rubella and varicella. Declining immune protection rates in younger individuals warrant immunization campaigns also targeting marginalized groups such as
homeless individuals. Given that herd immunity thresholds are not reached for individuals born after 1980 for measles, and after 1975 for mumps, vaccination campaigns should prioritize individuals within these age groups.