Hispanic population

西班牙裔人口
  • 文章类型: Journal Article
    背景肥胖患者患阻塞性睡眠呼吸暂停(OSA)的风险增加。减肥手术或减肥手术是肥胖患者体重和合并症管理的重要治疗措施。接受减肥手术的内城西班牙裔和黑人患者的数据很少,这最终导致了这个少数民族人口的健康差距。在该人群中没有评估有和没有OSA的患者之间的差异。本研究旨在回答这些问题。方法这项研究是在布朗克斯的一家高容量医院进行的,纽约减肥手术前,患者接受了术前评估,包括各种血液检查,睡眠研究,食管胃十二指肠镜检查,还有超声心动图.他们还接受了基本的人体测量,比如体重,高度,和体重指数(BMI),术前以及术后6个月和12个月。使用这些人体测量进行了额外的计算,即,总重量损失,过度减肥,和三角洲BMI。结果大多数患者为西班牙裔(85.2%),平均年龄41.9±10.8岁。我们发现,在研究中纳入的108名患者中,69.4%(70/108)患有OSA。术前BMI为43.9±13kg/m2。术后,BMI平均下降12.3±14.5kg/m2。总重量损失和过量重量损失分别为30.2±14.3和52.6±16.6。结论在这项研究中,有或没有OSA的患者在实验室或人体测量参数方面均无显著差异.
    Background Obese patients are at an increased risk of obstructive sleep apnea (OSA). Bariatric surgery or weight loss surgery is an important therapeutic measure in obese patients for the management of weight and comorbidities. Data are scarce in inner-city Hispanic and Black patients who undergo bariatric surgery, which eventually leads to health disparity in this minority population. Differences between patients with and without OSA have not been assessed in this population. This study aims to answer these questions. Methodology The study was conducted in a high-volume hospital in the Bronx, New York. Before bariatric surgery, patients underwent a preoperative evaluation that included a variety of blood tests, a sleep study, esophagogastroduodenoscopy, and echocardiography. They also underwent basic anthropometric measurements, such as weight, height, and body mass index (BMI), before surgery and 6 months and 12 months postoperatively. Additional calculations were made using these anthropometric measures, namely, total weight loss, excess weight loss, and delta BMI. Results Most patients were Hispanic (85.2%), with a mean age of 41.9 ± 10.8 years. We found that of the 108 patients included in the study, 69.4% (70/108) had OSA. Preoperative BMI in the study was 43.9 ± 13 kg/m2. Postoperatively, the mean decrease in BMI was 12.3 ± 14.5 kg/m2. Total weight loss and excess weight loss were 30.2 ± 14.3 and 52.6 ± 16.6, respectively. Conclusions In this study, no significant difference was noted in patients with or without OSA in either the laboratory or anthropometric parameters.
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  • 文章类型: Journal Article
    背景与目的高血压的发病率在全球范围内以惊人的速度增长。在美国,近一半的成年人患有高血压,一种可能与长期可怕后果和合并症相关的疾病。虽然互联网接入激增,在过去的二十年中,用于健康生活方式的免费基于互联网的教育资源呈指数增长,关于基于互联网的信息是否可以或被用作社区环境中高血压管理的自学工具,人们知之甚少。几乎没有公布的数据,如果以及在何种程度上基于互联网,自我导向学习工具用于高血压管理需要评估.鉴于此,我们的目的是评估互联网使用的患病率,作为已知诊断为高血压的患者的信息来源,这些患者提交给我们的德克萨斯理工大学健康科学中心的内科诊所,埃尔帕索.材料和方法我们进行了单中心,在我们教学医院内科诊所进行的基于队列的观察性研究。向所有已知诊断为高血压的18岁以上的成年人分发了调查问卷。所有参与者都同意参加。在研究的总人口中,93.6%(190/203)为西班牙裔。此外,67.5%(137/203)为女性。值得注意的是,22.7%(46/203)报告使用互联网了解高血压。互联网用户更年轻,平均年龄为61.4岁,而非互联网用户的平均年龄为68.7岁(p=0.02),就读于高等教育机构,并且大多从家人那里获得有关高血压的信息(91.3%vs2.5%,p<0.001)。虽然大多数患者使用互联网做出治疗决定,并对他们的选择感到满意,超过四分之一的人在使用基于互联网的资源后感到困惑和焦虑。结果研究中的大多数患者不使用互联网作为高血压管理的资源工具(157/203;77.3%)。在22.7%使用互联网进行高血压管理的患者中,最常用的资源是Google.com,作为高血压研究的第一步(26/46,58.6%,p<0.001),其次是提供的调查中预定列表中的多个资源(14/46,30.4%)。调查亦评估使用互联网资源的原因,主要原因是评估治疗方案(19/46,41.5%),其次是发展应对技能(13/46,28.2%),最后是协助决策(10/46,21.5%)。结论随着互联网变得越来越普遍,基于互联网的教育工具如雨后春笋般涌现。这项研究表明,在这个占主导地位的西班牙裔人口中,近四分之一的高血压患者使用互联网,自学工具。这凸显了医学教育的缓慢转变,提供者必须为此做好准备,因为患者将更频繁地使用这些工具作为医疗决策的辅助信息来源。需要进行进一步的研究来评估这些新信息来源的当前和纵向影响。
    Background and objective The incidence of hypertension is growing at an alarming rate globally. In the United States, nearly half of the adult population suffers from hypertension, a disease potentially associated with long-term dire consequences and comorbidities. While Internet access has proliferated, and free Internet-based education resources for healthy lifestyles have exponentially increased over the past two decades, little is known about whether Internet-based information can be or is used as a self-learning tool for hypertension management in a community setting. With almost no published data, if and to what degree Internet-based, self-directed learning tools are used for hypertension management needs to be assessed. In light of this, we aimed to evaluate the prevalence of Internet use as a source of information in patients with known diagnoses of hypertension who presented to our Internal Medicine clinic at Texas Tech University Health Sciences Center, El Paso. Materials and methods We conducted a single-center, cohort-based observational study at our teaching hospital\'s internal medicine clinic. A survey questionnaire was distributed to all adults aged more than 18 years with a known diagnosis of hypertension. Consent for participation was obtained from all participants. Of the total studied population, 93.6% (190/203) were of Hispanic descent. Moreover, 67.5% (137/203) identified as female. Of note, 22.7% (46/203) reported using the Internet to learn about hypertension. Internet users were younger, with a mean age of 61.4 years compared to 68.7 (p=0.02) years for non-Internet users, attended institutions of a higher grade of education, and mostly received information regarding hypertension from their families (91.3% vs 2.5%, p<0.001). While most patients used the Internet for making treatment decisions and were satisfied with their choices, more than a quarter felt confused and anxious after using Internet-based resources. Results Most patients in the study were found to not use the Internet as a resource tool for hypertension management (157/203; 77.3%). Among the 22.7% of patients who used the Internet for hypertension management, the most commonly utilized resource was Google.com, as an initial step to hypertension research (26/46, 58.6%, p<0.001), followed by multiple resources within a predetermined list on the provided survey (14/46, 30.4%). The survey also assessed the reasons for using Internet-based resources, with the primary reason being evaluating treatment options (19/46, 41.5%), followed by developing coping skills (13/46, 28.2%), and lastly aiding in decision-making (10/46, 21.5%). Conclusions Internet-based educational tools are mushrooming as the Internet is becoming more pervasive. This study shows that within this predominant Hispanic population, nearly one-quarter of patients with hypertension are using Internet-based, self-learning tools. This highlights a slow shift in medical education which providers have to be prepared for as patients will be using these tools as secondary information sources for medical decision-making more frequently going forward. Further studies need to be conducted to evaluate the current and longitudinal impact of these new information sources.
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  • 文章类型: Journal Article
    背景:西班牙裔占美国人口的19%,并且癌症发病率正在上升,主要是由于感染相关癌症的增加(胃癌,肝,宫颈癌)和晚期癌症继发于延迟筛查(结直肠癌,子宫颈,breast).胃癌的发病率增加(与感染有关,肥胖,酒精,和烟草使用)在西班牙裔,尤其是在年轻的时候,强调需要考虑种族作为一个风险因素。
    方法:本研究利用2016-2019年全国住院患者样本数据库检查所有胃癌患者。个人按种族分层,年龄,和合并症,包括与胃癌相关的可改变的危险因素。
    结果:年龄在18-44岁的患者为5,785(7.44%),年龄在45-64岁的患者为28,370(36.49%),65岁以上的患者为43,590(56.07%)。值得注意的是,34.3%的最年轻的群体是西班牙裔,与老年组的19.7%和12.9%相比,分别。与年龄较大的西班牙裔相比,年轻的西班牙裔患者的幽门螺杆菌感染率更高(8.6%)(中年组的3.6%和年龄最大的2.1%,p<0.01)。肥胖的患病率很高,烟草使用,和胃溃疡。其他危险因素如饮酒和胃息肉的患病率较低。
    结论:这项研究表明,西班牙裔患者的胃癌发病年龄较小,再加上年轻时幽门螺杆菌感染的发病率增加。这一发现强调了在无症状的年轻西班牙裔人群中进行幽门螺杆菌筛查的潜在益处,目的是降低该人群的胃癌发病率和死亡率。
    BACKGROUND: Hispanics make up 19% of the U.S. population and are experiencing rising rates of cancer, primarily due to an increase in infection-related cancers (gastric, hepatic, cervical) and advanced cancers secondary to delayed screening (colorectal, cervical, breast). There is an increased incidence of gastric cancer (associated with infection, obesity, alcohol, and tobacco use) in Hispanics, especially at a young age, highlighting the need to consider ethnicity as a risk factor.
    METHODS: This study utilized the 2016-2019 National Inpatient Sample database to examine all patients admitted with gastric cancer. Individuals were stratified by race, age, and comorbidities, including modifiable risk factors that are associated with gastric cancer.
    RESULTS: There were 5,785 (7.44%) patients aged 18-44, 28,370 (36.49%) aged 45-64, and 43,590 (56.07%) over 65 years of age. Notably, 34.3% of the youngest group were Hispanic, contrasted with 19.7% and 12.9% in the older groups, respectively. Younger Hispanic patients showed a higher prevalence of H. pylori infection (8.6%) compared with older Hispanics (3.6% in the middle age group and 2.1% in the oldest, p<0.01). There was a high prevalence of obesity, tobacco use, and gastric ulcers in this cohort. Other risk factors such as alcohol use and gastric polyps were present at a lesser prevalence.
    CONCLUSIONS: This study reveals that Hispanic patients tend to have a younger age of onset of gastric cancer, coupled with an increased incidence of H. pylori infection at a younger age. This finding underscores the potential benefit of H. pylori screening among asymptomatic young Hispanics with the aim of reducing gastric cancer morbidity and mortality in this population.
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  • 文章类型: Journal Article
    在与青少年饮酒和抑郁症相关的许多社会决定因素中,种族和族裔歧视是拉丁裔青少年和成年人中普遍存在的决定因素,在预防性干预措施中在很大程度上被忽视。这项研究探讨了拉丁裔青少年中种族和族裔歧视对抑郁症状和饮酒意向的影响。此外,该研究探讨了母亲感知的歧视如何影响青少年的抑郁症状和饮酒的跨代效应。该研究使用了800个多米尼加和波多黎各人在内城区的青少年-母亲二元组(青少年平均年龄=12.42岁,SD=0.81;母亲平均年龄=40.55岁,SD=8.70)。采用五波面板设计,跟随青少年从8年级到10年级,该研究发现,具有统计学意义的调解途径表明,青少年自我报告的种族和族裔歧视经历与他们近期和长期抑郁症状的增加有关,这反过来又与未来使用酒精的强烈意愿有关。Further,拉丁裔母亲所感受到的种族和族裔歧视与青少年未来饮酒意愿的增加有关,由母亲的抑郁症状和随后的青少年的抑郁症状介导。正如所讨论的,这些发现对针对城市内拉丁裔青少年的饮酒预防计划具有广泛的意义.
    Among the many social determinants linked to adolescent alcohol use and depression, racial and ethnic discrimination is a prevalent determinant among Latinx adolescents and adults that is largely overlooked in preventive interventions. This study explored the influence of perceived racial and ethnic discrimination on depressive symptoms and alcohol use intentions among Latinx adolescents. Additionally, the study explored the cross-generational effects of how mothers\' perceived discrimination impacts the depressive symptoms and alcohol use of the adolescent. The study used a sample of 800 inner-city Dominican and Puerto Rican adolescent-mother dyads (adolescent mean age = 12.42 years, SD = 0.81; mother mean age = 40.55 years, SD = 8.70). Employing a five-wave panel design that followed adolescents from 8th grade to 10th grade, the study found statistically significant mediation pathways which showed that adolescents\' self-reported racial and ethnic discrimination experiences were associated with increases in their immediate and long-term depressive symptoms, which in turn were associated with stronger intentions to use alcohol in the future. Further, perceived racial and ethnic discrimination experienced by Latinx mothers was associated with increases in adolescents\' intentions to drink alcohol in the future, mediated by the mothers\' depressive symptoms and subsequently the adolescents\' depressive symptoms. As discussed, these findings have wide-ranging implications for alcohol use prevention programs targeting inner-city Latinx adolescents.
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  • 文章类型: Journal Article
    目的:确定可能限制西班牙裔患者参与皮肤病学临床试验的因素。
    方法:从2022年1月到2022年7月,我们管理了31项,在Caridad中心等候区招募的患者的面对面问卷,美国最大的免费诊所之一,主要是西班牙裔人口,和附近的私人初级保健诊所.
    结果:总体而言,与非西班牙裔调查受访者相比,西班牙裔患者在态度和行为信念领域的陈述同意得更多。西班牙裔种族与同意以下陈述的可能性增加有关:“我的社区将真正从皮肤癌临床试验中受益”(OR=0.52;95%CI0.30,0.92),“我参与皮肤癌研究将非常好”(OR=0.59;95%CI0.35,0.99),和“我喜欢为他人做好事”(OR=0.41;95%CI0.22,0.77)。
    结论:虽然美国人口由18.5%的西班牙裔组成,他们仅占参加临床试验的患者的1%.这项研究有助于确定西班牙裔患者参与皮肤癌临床试验的潜在动机因素。
    OBJECTIVE: To determine the factors that might limit Hispanic patients from participating in dermatological clinical trials.
    METHODS: From January 2022 to July 2022, we administered a 31-item, in-person questionnaire to patients recruited in the waiting area of the Caridad Center, one of the largest free clinics in the United States with a predominately Hispanic population, and a nearby private primary care clinic.
    RESULTS: Overall, Hispanic patients agreed significantly more with statements in the domain of attitude and behavioral beliefs compared to non-Hispanic survey respondents. The Hispanic ethnicity was associated with increased odds of agreeing with the following statements: \"My community would really benefit from skin cancer clinical trials\" (OR=0.52; 95% CI 0.30, 0.92), \"My participation in a skin cancer study would be very good\" (OR=0.59; 95% CI 0.35, 0.99), and \"I like to do good for others\" (OR=0.41; 95% CI 0.22, 0.77).
    CONCLUSIONS: While the United States population is composed of 18.5% Hispanics, they only account for 1% of patients enrolled in clinical trials. This study helps identify potential motivational factors for Hispanic patients to participate in skin cancer clinical trials.
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  • 文章类型: Journal Article
    背景:COVID-19疫苗接种对于结束大流行至关重要,然而,孕妇和产后妇女仍然存在安全问题,尤其是那些黑人和西班牙裔。本研究旨在通过妇女的生活经历和产妇护理提供者(MCPs)观察,探讨影响产后妇女在怀孕和产后接种决策的因素。
    方法:从2022年1月至8月,我们对黑人和西班牙裔产后妇女以及MCP进行了半结构化访谈。参与者来自南卡罗来纳州的产科和儿科诊所,并于2021年分娩。数据分析采用主题分析。
    结果:该研究涉及19名黑人和20名西班牙裔女性,连同9个MCP,并揭示了COVID-19疫苗接种的障碍和促进因素。影响孕妇和产后妇女决定接种COVID-19疫苗的因素包括:1)对与COVID-19疫苗相关的健康威胁的认识,2)疫苗的可获得性和可及性,3)疫苗相关知识和接触错误信息,4)对COVID-19疫苗先前存在的健康状况和潜在副作用的担忧,5)与疫苗接种决策过程相关的情绪因素,6)关注婴儿的福祉,7)文化观点,和8)受信任的支持者的鼓励。
    结论:研究结果表明,可靠的信息,社会支持,值得信赖的MCP建议可以激励黑人和西班牙裔孕妇和产后妇女接种COVID-19疫苗。然而,诸如错误信息之类的障碍,医疗系统中的不信任,对潜在副作用的担忧阻碍了疫苗接种的吸收。未来的干预措施应该解决这些障碍,考虑健康差异,涉及可信的MCP,并开始关于疫苗的对话,以促进这些人群的疫苗接种。
    BACKGROUND: COVID-19 vaccination is vital for ending the pandemic, yet safety concerns persist among pregnant and postpartum women, especially those who are Black and Hispanic. This study aims to explore factors that influence postpartum women\'s vaccination decision-making during pregnancy and postpartum through women\'s lived experiences and maternal care providers\' (MCPs) observations.
    METHODS: From January to August 2022, we conducted semi-structured interviews with postpartum women who are Black and Hispanic and with MCPs. Participants were recruited from obstetric and pediatric clinics in South Carolina and had given birth in 2021. Thematic analysis was employed for data analysis.
    RESULTS: The study involved 19 Black and 20 Hispanic women, along with 9 MCPs, and revealed both barriers and facilitators to COVID-19 vaccination. The factors that influence pregnant and postpartum women\'s decision about COVID-19 vaccine uptake included: 1) awareness of health threats associated with COVID-19 vaccines, 2) vaccine availability and accessibility, 3) vaccine-related knowledge and exposure to misinformation, 4) concerns regarding pre-existing health conditions and potential side effects of COVID-19 vaccines, 5) emotional factors associated with vaccination decision-making processes, 6) concerns about the well-being of infants, 7) cultural perspectives, and 8) encouragement by trusted supporters.
    CONCLUSIONS: The findings suggest that reliable information, social support, and trusted MCPs\' advice can motivate COVID-19 vaccination among pregnant and postpartum women who are Black and Hispanic. However, barriers such as misinformation, mistrust in the health care system, and fears of potential side effects impede vaccination uptake. Future interventions should address these barriers, consider health disparities, involve trusted MCPs, and initiate conversations about vaccines to promote vaccination among these populations.
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  • 文章类型: Journal Article
    低健康素养(LHL)显著影响患者积极参与医疗保健的能力。注册护士(RN)在识别LHL和解决患者知识差距和技能缺陷方面发挥着至关重要的作用。这项相关研究检查了RNs对患者健康素养水平(HLL)的预测与主要是西班牙裔患者人群的实际HLL之间的关系。此外,个人因素(即,人口统计学)进行分析,以确定它们对护士的预测和患者的影响。数据是从84名参与者患者-护士对联中收集的数据,该对联被送往位于美国-墨西哥边境的农村地区的医疗外科部门。除了通过调查收集的人口统计信息,RNs被要求预测他们病人的健康素养能力,而最新的生命体征,健康素养评估工具,用于确定参与研究的患者的实际HLL。数据采用描述性统计分析,t检验,和卡方检验,同时使用Spearman相关模型来检验预测的HLL和实际HLL之间的关系。最后,使用logistic回归模型分析RNs和患者的个人因素与HL数据之间的关系.对数据的分析表明,RN始终高估了患者的能力,如患者实际HLL(平均1.71)和RN预测HLL(平均4.26)之间的差异所证明的,具有中等强度的正相关关系(rs=.418)。值得注意的是,较高的学术准备和多年的经验并不能增强RNs识别LHL的能力,而在抽样的患者人群中,最高教育水平是唯一具有统计学意义的健康素养充足的预测指标.这些发现强调,当临床环境中未使用标准化的健康素养评估工具时,需要在RN学术准备和临床实践中优先进行有效的健康素养教育,以支持LHL的检测。通过认识到LHL的存在,医疗保健专业人员可以更好地支持患者的需求,弥合知识差距,最终改善患者预后。
    Low health literacy (LHL) significantly impacts patients\' ability to participate actively in their healthcare. Registered nurses (RNs) play a crucial role in identifying LHL and addressing patient knowledge gaps and skill deficits. This correlational study examined the relationship between RNs\' predictions of patients\' health literacy levels (HLL) and the actual HLL of a predominately Hispanic patient population. In addition, personal factors (i.e., demographics) were analyzed to determine their influence on the nurse\'s predictions and patients\' HLL. Data were collected from 84 participant patient-nurse couplets admitted to a medical-surgical unit in a rural setting located on the United States-Mexico border. In addition to demographic information collected via survey, RNs were asked to predict their patient\'s health literacy abilities while the Newest Vital Sign, a health literacy assessment tool, was deployed to determine the actual HLL of patients participating in the study. Data were analyzed using descriptive statistics, t-tests, and chi-square tests while a Spearman correlational model was used to examine the relationship between predicted HLL and actual HLL. Finally, a logistic regression model was used to analyze the relationship between personal factors and HL data for RNs and patients. Analysis of the data revealed that RNs consistently overestimated patients\' abilities, as evidenced by the disparity between patients\' actual HLL (mean 1.71) and predicted HLL (mean 4.26) by RNs, with a moderately strong positive relationship (rs = .418). Notably, higher academic preparation and years of experience did not enhance the RNs\' ability to identify LHL while the highest level of education completed was the only statistically significant predictor of adequate health literacy in the patient population sampled. These findings emphasize the need to prioritize effective health literacy education in RN academic preparation and clinical practice to support the detection of LHL when a standardized health literacy assessment tool is not utilized in the clinical setting. By recognizing the presence of LHL, healthcare professionals can better support patients\' needs and bridge the knowledge gap, ultimately improving patient outcomes.
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  • 文章类型: Journal Article
    背景虽然农村地区和非农村地区的精神健康状况相似,农村地区获得精神保健的机会更加有限。在农村人口中,患者对特定心理健康治疗方案的态度尚未得到充分研究。以前的一些研究表明,使用整骨疗法(OMT)作为精神保健的辅助手段可能会带来积极的结果。使用OMT的医生在农村地区的比例更高。因此,了解农村的精神卫生治疗需求和选择偏好可以为政策提供信息,从而增加服务不足的人群获得各种精神卫生治疗方式,包括OMT。这项研究旨在描述患者对,关于信仰,以及对心理健康治疗的治疗选择的感知障碍,access,在农村护理,服务不足的临床环境。方法对2022年在单个门诊乡村诊所就诊四个月的成年患者进行参与筛查。该调查包括有关心理健康治疗方案的李克特量表分级问题,access,知识,以及感知到的障碍,包括关于OMT的定性问题。调查的版本是用英语和西班牙语创建的。结果在46名受访者中,25人讲英语,21人讲西班牙语。受访者最受欢迎的心理健康治疗被称为治疗,精神指引,改变饮食和锻炼。考虑到护理的障碍,61%的受访者表示治疗费用是后勤障碍。最后,80.5%的受访者对OMT没有很好的理解。结论患者对心理保健的感知态度和障碍的知识和理解,包括OMT,可以为临床医生提供洞察力,以改善患者的预后,并指导克服障碍的努力,以增加和扩大患者的心理健康治疗可用性和利用率。
    Background While the prevalence of mental health conditions is similar in rural areas and non-rural areas, access to mental health care is more limited in rural areas. Patient attitudes toward specific mental health treatment options in rural populations have been understudied. Some previous studies indicate potential positive outcomes using osteopathic manipulative treatment (OMT) as an adjunct for mental health care. Physicians using OMT are more heavily represented in rural areas. Hence, understanding the mental health treatment needs and option preferences of the rural could inform policies that increase underserved population\'s access to various mental health treatment modalities including OMT. This study aims to characterize patient attitudes toward, beliefs regarding, and perceived barriers to treatment options for mental health treatment, access, and care in a rural, underserved clinical setting. Methods Adult patients attending a single outpatient rural clinic over a four-month period in 2022 were screened for participation. The survey consisted of Likert scale graded questions about mental health treatment options, access, knowledge, and perceived barriers including qualitative questions about OMTs. Versions of the survey were created in English and Spanish languages. Results Out of 46 respondents, 25 were English-speaking and 21 were Spanish-speaking. The most popular mental health treatments by respondents were indicated as therapy, spiritual guidance, and modifying diet and exercise. Considering barriers to care, 61% of respondents indicated cost of treatment as a logistical barrier. Finally, 80.5% of respondents did not have a good understanding of OMT. Conclusions The knowledge and understanding of patients\' perceived attitudes and barriers toward mental health care, inclusive of OMT, can provide insight to clinicians to improve patient outcomes and guide efforts in overcoming barriers to increase and expand mental health treatment availability and utilization by patients.
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  • 文章类型: Journal Article
    睾丸癌(TCA)是一种罕见的恶性肿瘤,影响全球年轻男性。社会人口因素,特别是社会经济水平(SEL)和医疗保健准入,似乎影响TCA的发生率和结果,特别是在西班牙裔人群中。然而,有限的研究在西班牙裔人群中探索了这些变量。这项研究旨在调查墨西哥的社会人口统计学和临床因素及其在西班牙裔TCA患者健康差异中的作用。我们回顾性分析了2007年至2020年间来自国家参考癌症中心的具有不同社会背景的代表性队列的244例墨西哥TCA病例。Logistic回归确定死亡的危险因素:非精原细胞瘤组织学,高级阶段,和较低的教育水平。年龄作为危险因素表现出显著趋势。患者延误和医疗距离缺乏显著关联。在晚期,治疗反应不足和化疗耐药的可能性更大。而高等教育对治疗反应有积极影响。Cox回归突出非精原细胞瘤组织学,低于中位数的SEL,高等教育,和晚期生存率。基于肿瘤组织学和患者SEL出现生存差异。这项研究强调了整合社会人口统计学、生物,和环境因素来解决健康差异,通过个性化干预改善西班牙裔TCA患者的结局。
    Testicular cancer (TCa) is a rare malignancy affecting young men worldwide. Sociodemographic factors, especially socioeconomic level (SEL) and healthcare access, seem to impact TCa incidence and outcomes, particularly among Hispanic populations. However, limited research has explored these variables in Hispanic groups. This study aimed to investigate sociodemographic and clinical factors in Mexico and their role in health disparities among Hispanic TCa patients. We retrospectively analyzed 244 Mexican TCa cases between 2007 and 2020 of a representative cohort with diverse social backgrounds from a national reference cancer center. Logistic regression identified risk factors for fatality: non-seminoma histology, advanced stage, and lower education levels. Age showed a significant trend as a risk factor. Patient delay and healthcare distance lacked significant associations. Inadequate treatment response and chemotherapy resistance were more likely in advanced stages, while higher education positively impacted treatment response. Cox regression highlighted non-seminoma histology, below-median SEL, higher education, and advanced-stage survival rates. Survival disparities emerged based on tumor histology and patient SEL. This research underscores the importance of comprehensive approaches that integrate sociodemographic, biological, and environmental factors to address health disparities improving outcomes through personalized interventions in Hispanic individuals with TCa.
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  • 文章类型: Journal Article
    目标我们的目标是(1)确定种族与高危前列腺癌(PCa)生存率之间的关联,以及(2)确定这种关联是否被保险状态所改变。方法我们对2004年至2017年非西班牙裔白人(NHW)的国家癌症数据库(NCDB)进行了回顾性审查。西班牙裔白人(HW),或者有高危PCa的黑人.建立多变量Cox回归模型来检验总生存期(OS)与种族/民族之间的关系。保险状况,和他们的互动,控制各种社会经济和疾病特异性变量。结果共有94,708例高危PCa患者纳入分析。HW和黑人都具有较低的社会经济地位特征和较低的私人保险费率。在校正分析中,种族/民族与OS显著相关。只有Medicare表现出明显更差的OS。与HW男性相比,NHW(协变量调整后的风险比(aHR):1.83,95%CI:1.45-2.32)和Black(aHR:1.71,05%CI:1.34-2.19)男性的生存率明显较差。亚组分析表明,与没有保险的人相比,拥有私人保险/管理式护理的HW男性之间存在显着差异,医疗补助,Medicare,和其他政府保险类型。结论尽管存在社会经济和人口劣势,与NHW男子相比,HW男子表现出改进的操作系统。此外,在几乎每种保险状态类型中,与NHW男性相比,HW男性的OS有所改善。这一发现可能是复杂的多因素网络的结果,因此可以作为一个有趣的假设生成研究。
    Objectives Our objectives were to (1) determine the association between ethnicity and high-risk prostate cancer (PCa) survival and (2) determine whether this association is modified by insurance status. Methods We performed a retrospective review of the National Cancer Database (NCDB) from 2004 to 2017 of non-Hispanic White (NHW), Hispanic White (HW), or Black men with high-risk PCa. A multivariate Cox regression model was built to test the association between overall survival (OS) and race/ethnicity, insurance status, and their interaction, controlling for various socioeconomic and disease-specific variables. Results A total of 94,708 men with high-risk PCa were included in the analysis. Both HW and Black men had lower socioeconomic status characteristics and lower rates of private insurance. Race/ethnicity was significantly associated with OS in the adjusted analysis. Only Medicare demonstrated significantly worse OS. NHW (covariate-adjusted hazard ratio (aHR): 1.83, 95% CI: 1.45-2.32) and Black (aHR: 1.71, 05% CI: 1.34-2.19) men demonstrated significantly worse survival when compared to HW men. Subgroup analysis demonstrated significant differences occurring among HW men with private insurance/managed care when compared to those not insured, Medicaid, Medicare, and other government insurance types. Conclusion Despite socioeconomic and demographic disadvantages, HW men demonstrate improved OS compared to NHW men. Furthermore, HW men demonstrated improved OS compared to NHW men within nearly each insurance status type. This finding is likely the result of a complex multifactorial web and as such serves as an interesting hypothesis-generating study.
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