背景:被广泛认为是牛群疾病的主要原因之一,牛疱疹病毒-1(BoHV-1)具有感染绵羊和山羊的潜力,使它们成为这种病毒的潜在宿主或宿主。因此,牛针对BoHV-1的预防措施不应忽视该病毒感染其他动物的能力。
目标:因此,这项研究的重点是确定300只健康山羊中BoHV-1的血清阳性率,宿主和感染的环境决定因素之间的关系,以及山羊在BoHV-1流行病学中的作用。
方法:为了查明现有的BoHV-1抗体,通过病毒中和试验分析获得的血清。
结果:根据此测试,在伊朗西南部,BoHV-1的血清阳性率似乎为64.33%。什么逻辑回归披露的是,年龄和感染BoHV-1之间的比值比为0.83(p=0.01),随着山羊长大一岁,下降了17%。此外,与男性相比,女性表现出更高的相对感染频率,与雄性山羊相比,雌性山羊的感染几率为1.88(p=0.2)。此外,与没有流产史的山羊相比,有流产史的患者的比值比为1.1(p=0.87).亨迪扬的血清阳性率,Ahvaz,Shushtar和DashteAzadegan分别为73.24、71.30、55.56和47.06%,分别,在本研究的审查下,感染率的6%的波动归因于不同的地理位置(p=0.003)。
结论:在证明了BoHV-1的显著血清流行率之后,本研究证实了山羊作为该病毒的次要宿主或储库在流行病学中的决定性作用。在牛中BoHV-1丰富的地区,动物卫生当局必须严格监测山羊中的BoHV-1。
BACKGROUND: Widely regarded as one of the chief causes of diseases in cattle population, bovine herpesvirus-1 (BoHV-1) has the potential to infect sheep and goat, making them potential reservoirs or hosts for this virus. Thus, preventive measures against BoHV-1 in cattle should not overlook the ability of this virus to infect other animals.
OBJECTIVE: Therefore, the focal point of this study was to ascertain the seroprevalence of BoHV-1 in 300 healthy goats, the relationship between host and the environmental determinants of infection, and the contributing role of goats in the epidemiology of the BoHV-1.
METHODS: In order to pinpoint the existing antibodies to BoHV-1, the obtained sera were analyzed by Virus Neutralization test.
RESULTS: According to this test, the seroprevalence of BoHV-1 appeared to be 64.33% in southwestern Iran. What logistic regression disclosed was that the odds ratio between age and infection with BoHV-1 was 0.83 (p = 0.01), representing a decrease of 17% as goats grew one year older. In addition, females manifested a higher relative frequency of infection compared to males, with the odds of infection in female goats being registered at 1.88, compared to those in males (p = 0.2). Moreover, contrasted with goats lacking any history of abortion, those with a history of abortion featured 1.1 as the odds ratio (p = 0.87). The seroprevalence in Hendijan, Ahvaz, Shushtar and Dasht e Azadegan was detected to stand at 73.24, 71.30, 55.56 and 47.06 percent, respectively, with 6% of fluctuation in the infection rates being attributed to various geographical locations under the scrutiny of this study (p = 0.003).
CONCLUSIONS: Having attested the marked seroprevalence of BoHV-1, the definitive role of goats in the epidemiology of this virus as a secondary host or reservoir was confirmed by the present study, necessitating the strict monitoring of BoHV-1 in goats by animal health authorities in areas where BoHV-1 abounds in cattle.