■本系统评价的目的是评估临床,经济,与传统制备方法相比,与药物管理中使用预充式注射器相关的卫生资源利用结果。
■我们进行了系统的文献综述,以评估结果,例如用药错误,浪费,节省时间,和预充式注射器中的污染。我们的搜索包含多个数据库,包括PubMed和Embase,适用于2017年1月1日至2022年11月1日之间发表的研究。
■符合我们纳入标准的同行评审出版物经过严格筛选,包括标题,abstract,和全文文章评估,由两位评论家表演。
■在评论的文章中,24符合我们的资格标准。选定的研究主要是观察性的(46%),在欧洲进行(46%)。我们的研究结果表明,预充式注射器持续减少用药错误(10%-73%),不良事件(每100次给药1.1至0.275次),浪费(高达80%的药物),和准备时间(从4.0到338.0秒)(范围因药物类型而异,设置,和剂量)。然而,关于污染的数据有限。经济上,预充式注射器减少了浪费和错误率,这可能会转化为整体储蓄。
■这篇评论强调了预充式注射器的价值,这可以简化药物输送,节省护理时间,减少可预防的用药错误。此外,预充式注射器有可能最大限度地减少药物浪费,优化卫生保健环境中的资源利用和效率。
■我们的发现为采用预充式注射器的临床和经济效益提供了新的见解。这些好处包括改善药物输送和安全性,这可以减少医疗保健部门的时间和成本,医院,和卫生系统。然而,关于临床和经济结果的进一步现实世界研究,尤其是在污染方面,需要更好地了解预充式注射器的好处。
UNASSIGNED: The objective of this systematic review was to assess the clinical, economic, and health resource utilization outcomes associated with the use of prefilled syringes in medication administration compared with traditional preparation methods.
UNASSIGNED: We conducted a systematic literature review to evaluate outcomes such as medication errors, wastage, time savings, and contamination in prefilled syringes. Our search encompassed multiple databases, including PubMed and Embase, for studies published between January 1, 2017, and November 1, 2022.
UNASSIGNED: Peer-reviewed publications meeting our inclusion criteria underwent rigorous screening, including title, abstract, and full-text article assessments, performed by two reviewers.
UNASSIGNED: Among reviewed articles, 24 met our eligibility criteria. Selected studies were primarily observational (46%) and conducted in Europe (46%). Our findings indicated that prefilled syringes consistently reduced medication errors (by 10%-73%), adverse events (from 1.1 to 0.275 per 100 administrations), wastage (by up to 80% of drug), and preparation time (from 4.0 to 338.0 seconds) (ranges varied by drug type, setting, and dosage). However, there was limited data on contamination. Economically, prefilled syringes reduced waste and error rates, which may translate into overall savings.
UNASSIGNED: This review highlights the value of prefilled syringes, which can streamline medication delivery, save nursing time, and reduce preventable medication errors. Moreover, prefilled syringes have the potential to minimize medication wastage, optimizing resource utilization and efficiency in health care settings.
UNASSIGNED: Our findings provide new insights into clinical and economic benefits of prefilled syringe adoption. These benefits include improved medication delivery and safety, which can lead to time and cost reductions for health care departments, hospitals, and health systems. However, further real-world research on clinical and economic outcomes, especially in contamination, is needed to better understand the benefits of prefilled syringes.