■牙源性角化囊肿(OKCs)复发率高。我们旨在确定OKCs的复发模式以及非综合征和综合征患者中第二原发OKCs的发作。
■从1998年到2021年(23年)向我们部门报告的OKC患者使用人口统计进行回顾性评估,临床(年龄,性别,location,和尺寸),组织病理学,射线照相,和治疗数据。所有患者均随访>3年,并评估OKC复发。分别评估类痣基底细胞癌综合征(NBCCS)患者。
■我们纳入了非综合征性和综合征性OKC组中的38名和13名患者,分别。非综合征组和综合征组的复发率分别为15.8%和21.4%,分别为8.9%的患者表现出第二次复发和1.8%的患者表现出第三次复发。在非综合征组中未观察到第二原发性OKC;综合征组中76.9%的患者至少发展了一种。
■我们发现NBCCS患者的复发率高于非综合征性OKCs患者(21.4对15.8%)。与非综合征性OKC患者相比,NBCCS患者发生第二原发性OKC的可能性更高(76.9对0%)。没有发现OKC复发的统计学显著危险因素。
UNASSIGNED: Odontogenic keratocysts (OKCs) have high recurrence rates. We aimed to identify recurrence patterns in OKCs and the onset of second primary OKCs in non-syndromic and syndromic patients.
UNASSIGNED: Patients with OKCs reporting to our department from 1998 to 2021 (23 years) were retrospectively evaluated using demographic, clinical (age, sex, location, and size), histopathological, radiographic, and treatment data. All patients were followed-up for > 3 years and evaluated for OKC recurrence. Patients with naevoid basal cell carcinoma syndrome (NBCCS) were evaluated separately.
UNASSIGNED: We included 38 and 13 patients in the non-syndromic and syndromic OKC groups, respectively. The recurrence rates were 15.8 and 21.4% in the non-syndromic and syndromic groups, respectively; 8.9% of patients exhibited a second recurrence and 1.8% a third recurrence. No second primary OKCs were observed in the non-syndromic group; 76.9% of patients in the syndromic group developed at least one.
UNASSIGNED: We found a higher recurrence rate in patients with NBCCS compared with patients with non-syndromic OKCs (21.4 versus 15.8%). The probability of developing a second primary OKC in patients with NBCCS was higher compared with that in patients with non-syndromic OKCs (76.9 versus 0%). No statistically significant risk factors for OKC recurrence were identified.