PDF(Pubmed)
Abstract：
BACKGROUND: To demonstrate and analyze the 18F-FDG positron emission tomography/computed tomography (PET/CT) findings in this rare nevoid basal cell carcinoma syndrome (NBCCS).
METHODS: A 71-year-old woman with the left invasive breast cancer was treated with hormone therapy for six months and underwent the 18F-FDG PET/CT examination for efficacy evaluation. 18F-FDG PET/CT revealed the improvement after treatment and other unexpected findings, including multiple nodules on the skin with 18F-FDG uptake, bone expansion of cystic lesions in the bilateral ribs, ectopic calcifications and dilated right ureter. She had no known family history. Then, the patient underwent surgical excision of the all skin nodules and the postoperative pathology were multiple basal cell carcinomas. Finally, the comprehensive diagnosis of NBCCS was made. The patient was still in follow-up. Additionally, we have summarized the reported cases (n = 3) with 18F-FDG PET/CT from the literature.
CONCLUSIONS: It is important to recognize this syndrome on 18F-FDG PET/CT because of different diagnoses and therapeutic consequences.
METHODS: A 71-year-old woman with the left invasive breast cancer was treated with hormone therapy for six months and underwent the 18F-FDG PET/CT examination for efficacy evaluation. 18F-FDG PET/CT revealed the improvement after treatment and other unexpected findings, including multiple nodules on the skin with 18F-FDG uptake, bone expansion of cystic lesions in the bilateral ribs, ectopic calcifications and dilated right ureter. She had no known family history. Then, the patient underwent surgical excision of the all skin nodules and the postoperative pathology were multiple basal cell carcinomas. Finally, the comprehensive diagnosis of NBCCS was made. The patient was still in follow-up. Additionally, we have summarized the reported cases (n = 3) with 18F-FDG PET/CT from the literature.
CONCLUSIONS: It is important to recognize this syndrome on 18F-FDG PET/CT because of different diagnoses and therapeutic consequences.
摘要：
背景：为了证明和分析18F-FDG正电子发射断层扫描/计算机断层扫描（PET/CT）在这种罕见的中性基底细胞癌综合征（NBCCS）中的发现。
方法：一名71岁左侧浸润性乳腺癌患者接受激素治疗6个月，并接受18F-FDGPET/CT检查以评估疗效。18F-FDGPET/CT显示治疗后改善和其他意外发现，包括皮肤上有18F-FDG摄取的多个结节，双侧肋骨囊性病变的骨扩张，异位钙化和右输尿管扩张。她没有已知的家族史。然后，患者接受了所有皮肤结节的手术切除，术后病理为多发性基底细胞癌。最后,对NBCCS进行综合诊断。患者仍在随访中。此外,我们从文献中总结了18F-FDGPET/CT的报告病例（n=3）。
结论：由于不同的诊断和治疗结果，在18F-FDGPET/CT上识别该综合征很重要。
方法：一名71岁左侧浸润性乳腺癌患者接受激素治疗6个月，并接受18F-FDGPET/CT检查以评估疗效。18F-FDGPET/CT显示治疗后改善和其他意外发现，包括皮肤上有18F-FDG摄取的多个结节，双侧肋骨囊性病变的骨扩张，异位钙化和右输尿管扩张。她没有已知的家族史。然后，患者接受了所有皮肤结节的手术切除，术后病理为多发性基底细胞癌。最后,对NBCCS进行综合诊断。患者仍在随访中。此外,我们从文献中总结了18F-FDGPET/CT的报告病例（n=3）。
结论：由于不同的诊断和治疗结果，在18F-FDGPET/CT上识别该综合征很重要。
