以坚果为基础的产品可能有助于低血糖饮食策略,这对于血糖异常血症风险增加的人群预防糖尿病非常重要。比如亚洲华人。这项随机交叉试验评估了基于高蛋白坚果(HP-NB)零食配方的餐后血糖反应(0-120分钟),以条形格式(1009kJ,营养分析评分,NPS,-2),当与等能量高碳水化合物(CHO)谷物基棒(HC-CB,985kJ,NPS+3)。它还评估了抑制对典型的富含CHO的食物(白面包,WB),当共同摄取时。10名超重的糖尿病前期中国成年人(平均,sd:年龄47·9,15·7岁;BMI25·5,1·6kg/m2),使用双能X射线吸收法和磁共振成像和光谱学对全身脂肪加上异位胰腺和肝脏脂肪进行定量,按随机顺序接受了五餐治疗:HP-NB,HC-CB,HP-NB+WB(50g可用CHO),仅限HC-CB+WB和WB。与HC-CB相比,HP-NB诱导的30-120分钟葡萄糖反应显着降低(P<0·05),葡萄糖曲线下的增量面积降低约10倍(iAUC0-120;P<0·001)。当与WB共同摄入时,HP-NB还将葡萄糖反应减弱约25%(P<0·05)。一半的人胰腺和/或肝脏脂肪升高,在所有五种治疗中,低与高器官脂肪亚组对iAUC0-120葡萄糖的抑制增加13-21%。基于坚果的零食产品可能是能量等效的基于谷物的产品的更健康的替代品,具有较低的餐后血糖反应和CHO诱导的高血糖的调节,即使在高风险的情况下,超重,糖尿病前期的成年人。
Nut-based products may aid low-glycaemic dietary strategies that are important for diabetes prevention in populations at increased risk of dysglycaemia, such as Asian Chinese. This randomised cross-over trial assessed the postprandial glycaemic response (0-120 min) of a higher-protein nut-based (HP-NB) snack formulation, in bar format (1009 kJ, Nutrient Profiling Score, NPS, -2), when compared with an iso-energetic higher-carbohydrate (CHO) cereal-based bar (HC-CB, 985 kJ, NPS +3). It also assessed the ability to suppress glucose response to a typical CHO-rich food (white bread, WB), when co-ingested. Ten overweight prediabetic Chinese adults (mean, sd: age 47⋅9, 15⋅7 years; BMI 25⋅5, 1⋅6 kg/m2), with total body fat plus ectopic pancreas and liver fat quantified using dual-energy X-ray absorptiometry and magnetic resonance imaging and spectroscopy, received the five meal treatments in random order: HP-NB, HC-CB, HP-NB + WB (50 g available CHO), HC-CB + WB and WB only. Compared with HC-CB, HP-NB induced a significantly lower 30-120 min glucose response (P < 0⋅05), with an approximately 10-fold lower incremental area under the glucose curve (iAUC0-120; P < 0⋅001). HP-NB also attenuated glucose response by approximately 25 % when co-ingested with WB (P < 0⋅05). Half of the cohort had elevated pancreas and/or liver fat, with 13-21 % greater suppression of iAUC0-120 glucose in the low v. high organ fat subgroups across all five treatments. A nut-based snack product may be a healthier alternative to an energy equivalent cereal-based product with evidence of both a lower postprandial glycaemic response and modulation of CHO-induced hyperglycaemia even in high-risk, overweight, pre-diabetic adults.