我们描述了乌干达HIV感染患者的胚芽病。我们测试了福尔马林固定的,石蜡包埋的皮肤活检,通过对广谱真菌PCR扩增子进行测序,以鉴定巴斯德氏菌或密切相关的病原体。结果表明,与以前记录的相比,胚芽菌病更为广泛和遗传多样性。在组织块上进行PCR可能有助于阐明紧急真菌病的流行病学。
We describe emergomycosis in a patient in Uganda with HIV infection. We tested a formalin-fixed, paraffin-embedded skin biopsy to identify Emergomyces pasteurianus or a closely related pathogen by sequencing broad-range fungal PCR amplicons. Results suggest that emergomycosis is more widespread and genetically diverse than previously documented. PCR on tissue blocks may help clarify emergomycosis epidemiology.