未经证实:尽管一些关于颅面纤维骨损伤的研究已经测定了受影响患者的血清碱性磷酸酶水平,这些报告的结果往往没有定论。这项研究的目的是确定颅面纤维骨性病变(CFOL)患者的血清ALP水平与治疗结果之间的关系。
未经评估:在AhmaduBello大学教学医院就诊的连续患者,Zaria从五月,2016年12月,2017年,组织学诊断为CFOL的病变。采用了CFOLs的Speight和Carlos\(2006)分类,和患者的血清ALP水平和他们的年龄和性别匹配的明显健康的对照组在演示时进行测量,并且仅在术后第3个月和第6个月对受试者重复。治疗后6个月评估治疗结果。
UNASISIGNED:记录了50例CFOL,男性占优势,而纤维发育不良是最常见的病变,上颌骨是受影响最大的颌骨(62%)。只有11名受试者在就诊时血清ALP水平升高,CFOL受试者的平均血清ALP水平(341.2±198.1IU/L)高于年龄和性别匹配的对照组(190.7±110.2IU/L)。除了病变复发的受试者,治疗后第3个月(245±170.2IU/L)和第6个月(240.5±172.7IU/L)受试者的平均血清ALP水平下降.33名受试者消除了病变,而三例各复发或发病。
UNASSIGNED:纤维发育不良患者的治疗结果似乎与他们的血清ALP水平相关。因此,连续血清ALP水平监测建议用于颅面区纤维发育不良患者的治疗。
UNASSIGNED: Although some studies on craniofacial fibro-osseous lesions have assayed serum alkaline phosphatase levels of affected patients, the findings of these reports are often inconclusive. The aim of this study was to determine the association between the serum ALP levels of individuals with craniofacial fibro-osseous lesions (CFOLs) and treatment outcome.
UNASSIGNED: Consecutive patients who presented at the Ahmadu Bello University Teaching Hospital, Zaria from May, 2016 to December, 2017 with lesions histologically diagnosed as CFOLs. The Speight and Carlos\' (2006) classification of CFOLs was adopted, and the serum ALP level of patients and their age- and- gender matched apparently healthy controls were measured at presentation, and repeated at the 3rd and 6th post-operative months for subjects only. Treatment outcomes were assessed 6 months post treatment.
UNASSIGNED: Fifty cases of CFOLs were recorded with a male preponderance, while fibrous dysplasia was the most prevalent lesion, and the maxilla was the most affected jaw (62%). Only 11 subjects had elevated serum ALP levels at presentation, and the mean serum ALP level of subjects with CFOLs was higher (341.2 ± 198.1 IU/L) than that of their age-and gender-matched controls (190.7 ± 110.2 IU/L). With the exception of subjects whose lesions recurred, there was a decrease in the mean serum ALP levels of subjects by the 3rd (245 ± 170.2 IU/L) and 6th (240.5 ± 172.7 IU/L) months post-treatment. Thirty three subjects had elimination of lesions, while three cases each recurred or developed morbidity.
UNASSIGNED: The treatment outcomes of patients with fibrous dysplasia appear to be associated with their serum ALP level. Therefore, serial serum ALP level monitoring suggested in the management of patients with fibrous dysplasia of the craniofacial region.