PDF(Pubmed)
Abstract：
Cemento-ossifying fibroma (COF) is a benign odontogenic neoplasm. It is considered an ossifying fibroma with traces of interspersed cementum fragments. Here we present a case report of the occurrence of COF in the maxillary anterior region of an elderly woman. A 61-year-old female reported with a painless, progressive, slow-growing swelling on the upper front jaw region for the past five years. A single, localized, swelling on the anterior region of the maxilla which was non-tender and bony hard in consistency. Radiological examination consisting of orthopantomagram (OPG) and cone-beam computed tomography (CBCT) revealed increased thickness of bone over frontal, parietal and maxilla with alteration of trabecular pattern - cotton wool/ground glass. Serum alkaline phosphatase level was found to be 865 U/l, however, serum calcium level and other routine blood investigations (hemogram) were within normal limits. The above radiological and laboratory findings are more in favour of primary bone pathology and with a biopsy later correlating with histopathological findings; it was diagnosed as COF. Under conscious sedation, surgical excision of the bony mass was done along with extraction of associated teeth. The patient is currently on regular follow-up and planning for a dental prosthesis is in progress.
摘要：
骨化性纤维瘤（COF）是一种良性牙源性肿瘤。它被认为是骨化的纤维瘤，有散布的牙骨质碎片的痕迹。在这里，我们介绍了一名老年妇女上颌前区发生COF的病例报告。一名61岁的女性报告患有无痛症，进步,在过去的五年中，上颌区域的肿胀缓慢增长。单身,局部化,上颌骨前部肿胀，不嫩，骨硬。放射学检查包括正像图（OPG）和锥形束计算机断层扫描（CBCT）显示额骨厚度增加，顶骨和上颌骨小梁图案改变-棉绒/毛玻璃。血清碱性磷酸酶水平为865U/l，然而,血清钙水平和其他常规血液检查(血象)均在正常范围内.上述放射学和实验室发现更有利于原发性骨病理学，而活检后来与组织病理学发现相关；它被诊断为COF。在有意识的镇静下，手术切除骨块并拔除相关牙齿。该患者目前正在进行定期随访，并且正在计划进行假牙。
