Exostosis

外生症
  • 文章类型: Case Reports
    骨软骨瘤是最常见的骨良性肿瘤,可以是无柄的或有蒂的。虽然骨软骨瘤通常见于长骨,它们很少在手或脚的小骨头中看到。寻常疣,也被称为普通疣,是医生最常见的皮肤疾病之一,必须在临床或组织学上与其他过度角化疾病区分开来,包括骨骼疾病,如骨肿瘤,可以对皮肤施加压力,并导致骨痂形成,可以模仿疣或造成皮肤畸形。在评估患者的皮肤状况时,应考虑高度怀疑潜在的骨量或肿瘤。特别是手或脚,无法通过治疗改善。
    该病例报告介绍了一名20岁的男性,其左第四指骨远端有蒂骨软骨瘤,角化过度的皮肤覆盖脚趾末端的肿块。最初由家庭医生和足病医生治疗寻常疣超过5年,当治疗足病医生遇到骨骼和推荐的X光片时,他采用液氮冷冻疗法和手术切除肿块的两种治疗方法。几天后,家人被告知患者患有骨肿瘤后,要求对我们的实践进行随访。患者要求手术切除继发于疼痛的骨软骨瘤,其活动和作为飞行员的职业困难。
    所有医生都必须注意出现皮肤变化的患者的潜在骨肿瘤或肿块,尤其是脚或手。在评估和治疗患有皮肤病变的患者时,知道潜在的骨肿瘤可以表现为寻常疣,可以防止诊断延迟或不必要的治疗。幸运的是,我们的病例是良性骨软骨瘤;恶性肿瘤延迟诊断可能导致肢体或生命丧失.
    UNASSIGNED: Osteochondromas are the most common benign tumors of the bone and can be sessile or pedunculated. Although osteochondromas are typically seen in the long bones, they are rarely seen in the small bones of the hand or foot. Verruca vulgaris, also known as the common wart, is one of the most common skin conditions presenting to physicians and must be distinguished either clinically or histologically from other hyperkeratotic conditions, including bone conditions such as bone tumors that can place pressure on the skin and cause callus formation that can mimic a wart or create skin deformity. A high index of suspicion for underlying bone mass or tumor should be entertained when evaluating patients for skin conditions, particularly of the hand or foot, with failure to improve with treatment.
    UNASSIGNED: This case report presents a 20-year-old male with a pedunculated osteochondroma of the left fourth distal phalanx with hyperkeratotic skin overlying the mass at the end of the toe. He was initially treated by a family doctor and podiatrist for verruca vulgaris for over 5 years with two treatments of liquid nitrogen cryotherapy and surgical excision of the mass when the treating podiatrist encountered bone and recommended radiographs. The family requested follow-up with our practice several days later after they were told the patient had a bone tumor. The patient requested surgical excision of the osteochondroma secondary to pain with activities and difficulties with his vocation as a pilot.
    UNASSIGNED: All physicians must be mindful of an underlying bone tumor or mass in patients presenting with skin changes, particularly about the foot or hand. Knowledge that an underlying bone tumor can present as a verruca vulgaris may prevent a delay in diagnosis or unnecessary treatment when evaluating and treating a patient with a skin lesion. Fortunately, our case was a benign osteochondroma; a malignant tumor with a delay in diagnosis could lead to loss of limb or life.
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  • 文章类型: Case Reports
    我们介绍了一例遗传性多发性外生骨,并伴有恶性转化为软骨肉瘤的妇女,该妇女抱怨右大腿肿大和疼痛。遗传性多发性骨外生症是一种罕见的遗传性疾病,以多发性骨软骨瘤为特征。预先存在的骨软骨瘤向软骨肉瘤的恶性转化是这种遗传性综合征的可能的重要表现。成像模式,如X射线,超声波,计算机断层扫描在这些患者的诊断和治疗中起着至关重要的作用,正如在这种情况下所描述的。
    We present a case of hereditary multiple exostoses with malignant transformation to chondrosarcoma in a woman complaining of enlargement and pain in the right thigh. Hereditary multiple exostoses is a rare genetic disorder characterized by multiple osteochondromas. Malignant transformation to chondrosarcoma of a pre-existing osteochondroma is a possible significant manifestation of this hereditary syndrome. Imaging modalities such as X-ray, Ultrasound, and computed tomography play a crucial role in the diagnosis and management of these patients, as described in this case.
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    文章类型: Case Reports
    UNASSIGNED: Alveolar oral exostosis is a common, benign condition routinely found in dentistry. Clinical problems associated with exostoses are the maintenance of oral hygiene as well as the fabrication of prosthodontic appliances. Over time, exostoses may contribute to irritation and periodontal disease.
    UNASSIGNED: The patient in this case study had a recurrence of exostoses and was bothered by consistent and prominent pain. She reported being a bruxer; her bruxism was exacerbated due to attention-deficit hyperactivity disorder and antidepressant medications.
    UNASSIGNED: The etiology behind the recurrence of exostosis is discussed. The most evident etiology seems to be persistence of medication-induced bruxism, specifically awake bruxism.
    UNASSIGNED: It is necessary to take a proper history to identify the cause of the recurrence of exostosis. Dental hygienists can contribute to a better understanding of and provide better treatment options for patients who have medication-induced bruxism.
    UNASSIGNED: L’exostose buccale alvéolaire est une affection bénigne courante couramment observée en dentisterie. Les problèmes cliniques associés aux exostoses sont le maintien de l’hygiène buccale ainsi que la fabrication d’appareils prosthodontiques. Avec le temps, les exostoses peuvent causer de l’irritation et des maladies parodontales.
    UNASSIGNED: Dans cette étude de cas, la patiente présente des exostoses récurrentes et est dérangée par une douleur constante et proéminente. Elle a déclaré souffrir de bruxisme exacerbé par la prise de médicaments antidépresseurs et contre le trouble déficitaire de l’attention avec hyperactivité.
    UNASSIGNED: L’étiologie derrière la récurrence de l’exostose est abordée. L’étiologie la plus évidente semble être la persistance du bruxisme induit par les médicaments, en particulier le bruxisme diurne.
    UNASSIGNED: Il est nécessaire d’obtenir les antécédents médicaux appropriés pour identifier la cause de la récurrence de l’exostose. Les hygiénistes dentaires peuvent contribuer à une meilleure compréhension et offrir de meilleures options de traitement aux patients atteints de bruxisme induit par les médicaments.
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  • 文章类型: Journal Article
    一名30岁的男子出现右小腿疼痛和明显的固体肿块。放射学成像显示,右侧腓骨远端有外生性肿块引起的骨膜反应。在影像学骨骼检查中发现了具有骨膜反应的广义骨骼骨硬化。右腓骨肿块的活检显示反应性编织骨。病人被转诊到代谢性骨病诊所,其中实验室值与继发性甲状旁腺功能亢进和骨转换增加一致。DXA骨密度扫描显示骨密度高,L1-4脊柱Z评分为+9.3,左股骨颈Z评分为+8.5,总髋关节Z评分为+6.5。牙科检查显示全身牙龈发炎,牙齿的流动性,广泛的水平牙槽骨丢失和牙周膜间隙的扩大,牙齿周围的骨密度增加,和神经根膜硬膜增厚。进行了广泛的评估,单一测试的结果揭示了诊断。骨硬化影响骨骼的鉴别诊断,牙齿,和口腔进行了讨论。
    一个30岁的男人开发,在短时间内,他的右小腿疼痛伴有硬块。他还报告了过去6个月的体重减轻和盗汗。经过他的主治医生的评估,下令进行X射线检查,报告右腓骨骨产生骨块。对肿块进行了活检,但没有发现癌症或任何其他特定异常的证据。然后将患者转诊到骨病专科诊所。实验室测试显示,患者骨骼重塑的速度大幅增加,影响维持健康骨骼的骨形成和去除的平衡。骨密度扫描报告患者的骨骼非常致密。在牙科检查中还发现了其他不寻常的变化,提示骨增厚.经过广泛的评估,一次血液检查显示腓骨骨量和致密骨骼的原因。
    A 30-yr-old man developed right lower leg pain and a palpable solid mass. Radiographic imaging revealed a periosteal reaction with an exostotic mass arising from the right distal fibula. Generalized skeletal osteosclerosis with periosteal reaction was discovered on a radiographic skeletal survey. A biopsy of the right fibular mass revealed reactive woven bone. The patient was referred to a metabolic bone disease clinic, where laboratory values were consistent with secondary hyperparathyroidism and increased bone turnover. A DXA bone density scan revealed high bone density, with an L1-4 spine Z-score of +9.3, a left femoral neck Z-score of +8.5, and a total hip Z-score of +6.5. A dental exam revealed generalized gingival inflammation, teeth mobility, generalized horizontal alveolar bone loss and widening of the periodontal ligament space, increased bone density around the teeth, and thickening of the radicular lamina dura. An extensive evaluation was performed, with the result of a single test revealing the diagnosis. The differential diagnoses of osteosclerosis affecting the skeleton, teeth, and oral cavity are discussed.
    A 30-yr-old man developed, over a short period, pain in his lower right leg accompanied by a hard mass. He also reported weight loss and night sweats for the past 6 months. After evaluation by his primary physician, an X-ray was ordered that reported a bony mass arising from the right fibula bone. A biopsy was performed of the mass, but no evidence of cancer or any other specific abnormality was found. The patient was then referred to a bone disease specialty clinic. Laboratory tests revealed a large increase in how quickly the patient’s skeleton was remodeling, affecting the balance of bone formation and removal involved in maintaining a healthy skeleton. A bone density scan reported that the patient had very dense bones. Other unusual changes were also discovered in a dental exam, suggesting bone thickening. After an extensive evaluation, a single blood test revealed the cause of the fibular bone mass and dense bones.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    骨软骨瘤是良性骨肿瘤,通常发生在10至30岁之间,没有明显的性别偏好。这些病变是由骨phy生长板的分离引起的,被归类为生长板发育异常,而不是真正的肿瘤。值得注意的是,长期孤立性骨软骨瘤可以演变成骨肉瘤,其中最常见的是软骨肉瘤。然而,如果肿瘤从其原始部位完全切除,则复发的风险大大降低,没有残留的软骨膜或软骨帽。在这种情况下,一名29岁的股骨远端骨软骨瘤患者通过完全切除成功治疗,表现出有利的进化。
    Osteochondromas are benign bone tumors that usually occur between the ages of 10 and 30, with no marked gender preference. These lesions result from the separation of the epiphyseal growth plate and are categorized as growth plate development abnormalities rather than true neoplasms. It is important to note that long-term solitary osteochondromas can evolve into osteosarcomas, with chondrosarcoma being the most common among them. However, the risk of recurrence is considerably reduced if the tumor is completely resected from its original site, with no residual perichondrium or cartilage cap left in place. In this context, a 29-year-old man with osteochondroma in the distal femur was successfully treated with complete resection, showing a favorable evolution.
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  • 文章类型: Case Reports
    此病例报告显示,在一名15岁的女性中,与左前臂发育畸形相关的尺骨外生症很少发生。该患者报告有创伤史,导致肱骨髁上骨折在8年前保守治疗。患者有两年的左前臂疼痛和肿胀病史。临床检查显示,非招标,不动的肿胀与尺骨密切相关,伴有20度肘内翻畸形和前臂缩短。射线照片和计算机断层扫描证实尺骨轴上存在孤立的外部骨突起,与髓腔相通。根据临床和影像学发现,对骨软骨瘤进行了初步诊断。患者在锁骨上神经阻滞麻醉下接受骨外整块切除术。组织病理学检查证实了诊断。开始术后物理治疗,在一个月的随访中,患者报告无痛。此病例突出了尺骨外生性的罕见性,并伴有发育畸形,强调全面诊断方法的重要性。早期手术干预导致成功的结果,强调及时管理对改善患者预后和生活质量的重要性。
    This case report presents a rare occurrence of exostosis of the ulna associated with a developmental deformity of the left forearm in a 15-year-old female. The patient reported a history of trauma resulting in a supracondylar humerus fracture managed conservatively eight years prior. The patient presented with a two-year history of pain and swelling over the left forearm. Clinical examination revealed a firm, non-tender, immobile swelling closely associated with the ulna, accompanied by a 20-degree cubitus varus deformity and forearm shortening. Radiographs and computed tomography scans confirmed the presence of a solitary external bony protuberance over the ulna shaft, communicating with the medullary cavity. A preliminary diagnosis of osteochondroma was established based on clinical and imaging findings. The patient underwent extraperiosteal en bloc resection of the lesion under supraclavicular nerve block anesthesia. A histopathological examination confirmed the diagnosis. Postoperative physiotherapy was initiated, and at the one-month follow-up, the patient reported being pain-free. This case highlights the rarity of exostosis of the ulna with associated developmental deformity, emphasizing the importance of a comprehensive diagnostic approach. Early surgical intervention resulted in a successful outcome, underscoring the significance of timely management in improving patient outcomes and quality of life.
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  • 文章类型: Case Reports
    骨软骨瘤(OC)是由透明软骨覆盖的软骨和髓质骨组成的骨病变。骨phy生长板软骨分离产生OCs,穿过骨膜骨袖.它们通常在长骨的干phy端表现为带蒂或无蒂肿块,是最常见的良性骨肿瘤。虽然在肩胛骨很少见,OCs可以在那里发生。骨折可能会引起症状,骨异常,或者潜在的恶性转化,特别是在遗传性多发性外生骨(HME)的存在。孤立性病变的恶性转化率估计为1%,而在遗传性多发性OCs中,它可以达到3-5%。我们报告了一例10岁的女性,她的右肩胛骨后部逐渐肿胀。在过去两年的过程中观察到这种逐渐增长并伴有轻度疼痛。疼痛是间歇性的,不影响她的日常活动。在检查中,一个硬,tender,在右肩胛骨上发现约2×2cm的非活动肿胀。患者的肩部和肩胸区域的活动范围正常。总之,由于孤立的肩胛骨OCs极为罕见,当与HME相关联时,它们是相当常见的。这项研究旨在提高对OC异常位点的认识。此外,我们已经全面介绍了我们对该患者进行的手术治疗,以帮助未来可能遇到类似疾病的外科医生。
    Osteochondromas (OCs) are bone lesions composed of cartilaginous and medullary bone capped with hyaline cartilage. OCs result from the separation of epiphyseal growth plate cartilage, pushing through the periosteal bone cuff. They commonly appear as pedunculated or sessile masses in the metaphysis of long bones and are the most common benign bone tumors. While rare in the scapula, OCs can occur there. Symptoms may arise from fractures, osseous abnormalities, or potential malignant transformation, especially in the presence of hereditary multiple exostoses (HME). The estimated rate of malignant transformation in solitary lesions is 1%, whereas in hereditary multiple OCs, it can reach up to 3-5%. We report a case of a 10-year-old female who presented with a gradually progressive swelling on the back of her right scapula. This progressive growth has been observed over the course of the past two years accompanied by mild pain. The pain was intermittent and did not affect her daily activities. On examination, a hard, tender, non-mobile swelling of approximately 2 × 2 cm was found over the right scapula. The patient had a normal range of motion in the shoulder and scapulothoracic regions. In conclusion, since solitary scapular OCs are extremely rare, they are quite common when associated with HME. This study aimed to increase awareness of the unusual site of OCs. Furthermore, we have included a full account of the surgical therapy we administered to this patient in order to assist future surgeons who may come across similar conditions.
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  • 文章类型: Case Reports
    骨外生症(又称骨软骨瘤)是年轻人最常见的良性骨性肿块,通常出现在股骨远端。与外生体相关的血管并发症很少见,包括真正的动脉瘤或假性动脉瘤形成。深静脉血栓形成,动静脉瘘,和四肢动脉供血不足.很少有病例报告描述成熟成人外生体引起的假性动脉瘤。尚未就最佳治疗达成共识。我们报告了一个51岁的男性患者,抱怨持续的右大腿疼痛伴搏动性肿块和右小腿肿胀,没有外伤或遗传性多发性外生骨。诊断通过计算机断层扫描血管造影证实,显示股骨远端外侧的骨外生症导致pop动脉假性动脉瘤。多普勒超声检查证实了由假性动脉瘤压迫引起的the静脉血栓形成。手术治疗包括切除外生体,切除假性动脉瘤,和端到端吻合。深静脉血栓使用利伐沙班治疗3个月。6天后出院,随访6个月,效果满意。
    Exostosis (also known as osteochondroma) is the most common benign bony lump of young people, usually arising at the distal femur. Vascular complications associated with exostoses are rare and include true aneurysm or pseudoaneurysm formation, deep vein thrombosis, arteriovenous fistula, and arterial insufficiency of the limbs. Few case reports describe pseudoaneurysms resulting from exostoses in mature adults, and no consensus has been reached regarding the optimal therapy. We report the case of a 51-year-old male patient complaining of persistent right thigh pain with a pulsatile mass and right calf swelling, without a history of trauma or hereditary multiple exostoses. The diagnosis was confirmed by computed tomography angiography, which showed a pseudoaneurysm of the popliteal artery resulting from an exostosis on the lateral aspect of the distal femur. A Doppler ultrasound examination confirmed popliteal vein thrombosis caused by the compression of the pseudoaneurysm. Surgical treatment consisted of removing the exostosis, excision of the pseudoaneurysm, and an end-to-end anastomosis. The deep vein thrombosis was treated with rivaroxaban for 3 months. The patient was discharged after 6 days and followed up for 6 months with satisfactory results.
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    文章类型: Journal Article
    背景:儿童和年轻人的指尖上有大量的电子设备。虽然它可以提供无尽的娱乐和教育时间,我们还看到了结构性后果。儿童使用这些设备时,头部向下倾斜,姿势不佳,导致附件结构对颅骨的应力增加,这可能导致枕骨外突起(EOP)处的骨刺(外生骨)。虽然通常是无痛的,它可以发展到需要手术干预。
    目的:本研究的目的是了解外生骨外生在EOP中的患病率以及该发现如何影响核医学骨扫描。
    方法:43例接受1年全身骨扫描的儿科患者(10-19岁)被纳入研究。由2位经过董事会认证的核医学医师审查了图像,以评估枕骨颅骨中线的摄取。对可疑病例进行随访,并提供所有可用的临床和影像学报告和图像。
    结果:骨扫描显示43例患者中有7例(16%)存在枕骨摄取病灶(5例男性,2例女性,平均年龄15岁;范围10-19)。其中,5/7(71%)通过额外的成像证实。
    结论:快速发展的技术正在导致儿童和年轻人的屏幕时间增加。我们的研究表明,在我们的设施中,年龄在10-19岁之间的儿科人群中有16%在EOP中有外生体的迹象。对于临床医生来说,在阅读骨骼扫描时了解此实体以避免假阳性解释尤为重要。
    BACKGROUND: Children and young adults have a vast array of electronics at their fingertips. While it can provide endless hours of entertainment and education, we are also seeing a structural consequence. Children are using these devices with their head tilted down with poor posture resulting in increased stress on the skull from attached structures which can lead to a bone spur (exostosis) at the external occipital protuberance (EOP). While typically painless, it can progress to necessitate surgical intervention.
    OBJECTIVE: The purpose of this study is to understand the prevalence of exostosis at the EOP and how the finding can affect the nuclear medicine bone scan.
    METHODS: 43 pediatric patients who underwent a whole-body bone scan over a period of 1 year were included in the study (10-19 years old). Images were reviewed by 2 board-certified Nuclear Medicine physicians to assess for uptake midline in the occipital skull. Suspected cases were followed up with all available clinical and radiographic reports and images.
    RESULTS: Bone scan demonstrated an occipital focus of uptake in 7 (16%) of the 43 patients (5 males and 2 females with a mean age of 15 years; range 10-19). Of these, 5/7 (71%) were confirmed by additional imaging.
    CONCLUSIONS: The rapidly advancing technology is leading to increased screen time in children and young adults. Our study shows that 16% of the pediatric population imaged at our facility between the ages of 10-19 years have signs of exostosis at the EOP. It is particularly important for clinicians to be aware of this entity when reading bone scans to avoid false positive interpretations.
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