Exostosis

外生症
  • 文章类型: Case Reports
    骨软骨瘤是最常见的骨良性肿瘤,可以是无柄的或有蒂的。虽然骨软骨瘤通常见于长骨,它们很少在手或脚的小骨头中看到。寻常疣,也被称为普通疣,是医生最常见的皮肤疾病之一,必须在临床或组织学上与其他过度角化疾病区分开来,包括骨骼疾病,如骨肿瘤,可以对皮肤施加压力,并导致骨痂形成,可以模仿疣或造成皮肤畸形。在评估患者的皮肤状况时,应考虑高度怀疑潜在的骨量或肿瘤。特别是手或脚,无法通过治疗改善。
    该病例报告介绍了一名20岁的男性,其左第四指骨远端有蒂骨软骨瘤,角化过度的皮肤覆盖脚趾末端的肿块。最初由家庭医生和足病医生治疗寻常疣超过5年,当治疗足病医生遇到骨骼和推荐的X光片时,他采用液氮冷冻疗法和手术切除肿块的两种治疗方法。几天后,家人被告知患者患有骨肿瘤后,要求对我们的实践进行随访。患者要求手术切除继发于疼痛的骨软骨瘤,其活动和作为飞行员的职业困难。
    所有医生都必须注意出现皮肤变化的患者的潜在骨肿瘤或肿块,尤其是脚或手。在评估和治疗患有皮肤病变的患者时,知道潜在的骨肿瘤可以表现为寻常疣,可以防止诊断延迟或不必要的治疗。幸运的是,我们的病例是良性骨软骨瘤;恶性肿瘤延迟诊断可能导致肢体或生命丧失.
    UNASSIGNED: Osteochondromas are the most common benign tumors of the bone and can be sessile or pedunculated. Although osteochondromas are typically seen in the long bones, they are rarely seen in the small bones of the hand or foot. Verruca vulgaris, also known as the common wart, is one of the most common skin conditions presenting to physicians and must be distinguished either clinically or histologically from other hyperkeratotic conditions, including bone conditions such as bone tumors that can place pressure on the skin and cause callus formation that can mimic a wart or create skin deformity. A high index of suspicion for underlying bone mass or tumor should be entertained when evaluating patients for skin conditions, particularly of the hand or foot, with failure to improve with treatment.
    UNASSIGNED: This case report presents a 20-year-old male with a pedunculated osteochondroma of the left fourth distal phalanx with hyperkeratotic skin overlying the mass at the end of the toe. He was initially treated by a family doctor and podiatrist for verruca vulgaris for over 5 years with two treatments of liquid nitrogen cryotherapy and surgical excision of the mass when the treating podiatrist encountered bone and recommended radiographs. The family requested follow-up with our practice several days later after they were told the patient had a bone tumor. The patient requested surgical excision of the osteochondroma secondary to pain with activities and difficulties with his vocation as a pilot.
    UNASSIGNED: All physicians must be mindful of an underlying bone tumor or mass in patients presenting with skin changes, particularly about the foot or hand. Knowledge that an underlying bone tumor can present as a verruca vulgaris may prevent a delay in diagnosis or unnecessary treatment when evaluating and treating a patient with a skin lesion. Fortunately, our case was a benign osteochondroma; a malignant tumor with a delay in diagnosis could lead to loss of limb or life.
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    文章类型: Case Reports
    UNASSIGNED: Alveolar oral exostosis is a common, benign condition routinely found in dentistry. Clinical problems associated with exostoses are the maintenance of oral hygiene as well as the fabrication of prosthodontic appliances. Over time, exostoses may contribute to irritation and periodontal disease.
    UNASSIGNED: The patient in this case study had a recurrence of exostoses and was bothered by consistent and prominent pain. She reported being a bruxer; her bruxism was exacerbated due to attention-deficit hyperactivity disorder and antidepressant medications.
    UNASSIGNED: The etiology behind the recurrence of exostosis is discussed. The most evident etiology seems to be persistence of medication-induced bruxism, specifically awake bruxism.
    UNASSIGNED: It is necessary to take a proper history to identify the cause of the recurrence of exostosis. Dental hygienists can contribute to a better understanding of and provide better treatment options for patients who have medication-induced bruxism.
    UNASSIGNED: L’exostose buccale alvéolaire est une affection bénigne courante couramment observée en dentisterie. Les problèmes cliniques associés aux exostoses sont le maintien de l’hygiène buccale ainsi que la fabrication d’appareils prosthodontiques. Avec le temps, les exostoses peuvent causer de l’irritation et des maladies parodontales.
    UNASSIGNED: Dans cette étude de cas, la patiente présente des exostoses récurrentes et est dérangée par une douleur constante et proéminente. Elle a déclaré souffrir de bruxisme exacerbé par la prise de médicaments antidépresseurs et contre le trouble déficitaire de l’attention avec hyperactivité.
    UNASSIGNED: L’étiologie derrière la récurrence de l’exostose est abordée. L’étiologie la plus évidente semble être la persistance du bruxisme induit par les médicaments, en particulier le bruxisme diurne.
    UNASSIGNED: Il est nécessaire d’obtenir les antécédents médicaux appropriés pour identifier la cause de la récurrence de l’exostose. Les hygiénistes dentaires peuvent contribuer à une meilleure compréhension et offrir de meilleures options de traitement aux patients atteints de bruxisme induit par les médicaments.
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  • 文章类型: Case Reports
    骨软骨瘤是良性骨肿瘤,通常发生在10至30岁之间,没有明显的性别偏好。这些病变是由骨phy生长板的分离引起的,被归类为生长板发育异常,而不是真正的肿瘤。值得注意的是,长期孤立性骨软骨瘤可以演变成骨肉瘤,其中最常见的是软骨肉瘤。然而,如果肿瘤从其原始部位完全切除,则复发的风险大大降低,没有残留的软骨膜或软骨帽。在这种情况下,一名29岁的股骨远端骨软骨瘤患者通过完全切除成功治疗,表现出有利的进化。
    Osteochondromas are benign bone tumors that usually occur between the ages of 10 and 30, with no marked gender preference. These lesions result from the separation of the epiphyseal growth plate and are categorized as growth plate development abnormalities rather than true neoplasms. It is important to note that long-term solitary osteochondromas can evolve into osteosarcomas, with chondrosarcoma being the most common among them. However, the risk of recurrence is considerably reduced if the tumor is completely resected from its original site, with no residual perichondrium or cartilage cap left in place. In this context, a 29-year-old man with osteochondroma in the distal femur was successfully treated with complete resection, showing a favorable evolution.
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  • 文章类型: Case Reports
    此病例报告显示,在一名15岁的女性中,与左前臂发育畸形相关的尺骨外生症很少发生。该患者报告有创伤史,导致肱骨髁上骨折在8年前保守治疗。患者有两年的左前臂疼痛和肿胀病史。临床检查显示,非招标,不动的肿胀与尺骨密切相关,伴有20度肘内翻畸形和前臂缩短。射线照片和计算机断层扫描证实尺骨轴上存在孤立的外部骨突起,与髓腔相通。根据临床和影像学发现,对骨软骨瘤进行了初步诊断。患者在锁骨上神经阻滞麻醉下接受骨外整块切除术。组织病理学检查证实了诊断。开始术后物理治疗,在一个月的随访中,患者报告无痛。此病例突出了尺骨外生性的罕见性,并伴有发育畸形,强调全面诊断方法的重要性。早期手术干预导致成功的结果,强调及时管理对改善患者预后和生活质量的重要性。
    This case report presents a rare occurrence of exostosis of the ulna associated with a developmental deformity of the left forearm in a 15-year-old female. The patient reported a history of trauma resulting in a supracondylar humerus fracture managed conservatively eight years prior. The patient presented with a two-year history of pain and swelling over the left forearm. Clinical examination revealed a firm, non-tender, immobile swelling closely associated with the ulna, accompanied by a 20-degree cubitus varus deformity and forearm shortening. Radiographs and computed tomography scans confirmed the presence of a solitary external bony protuberance over the ulna shaft, communicating with the medullary cavity. A preliminary diagnosis of osteochondroma was established based on clinical and imaging findings. The patient underwent extraperiosteal en bloc resection of the lesion under supraclavicular nerve block anesthesia. A histopathological examination confirmed the diagnosis. Postoperative physiotherapy was initiated, and at the one-month follow-up, the patient reported being pain-free. This case highlights the rarity of exostosis of the ulna with associated developmental deformity, emphasizing the importance of a comprehensive diagnostic approach. Early surgical intervention resulted in a successful outcome, underscoring the significance of timely management in improving patient outcomes and quality of life.
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  • 文章类型: Case Reports
    骨软骨瘤(OC)是由透明软骨覆盖的软骨和髓质骨组成的骨病变。骨phy生长板软骨分离产生OCs,穿过骨膜骨袖.它们通常在长骨的干phy端表现为带蒂或无蒂肿块,是最常见的良性骨肿瘤。虽然在肩胛骨很少见,OCs可以在那里发生。骨折可能会引起症状,骨异常,或者潜在的恶性转化,特别是在遗传性多发性外生骨(HME)的存在。孤立性病变的恶性转化率估计为1%,而在遗传性多发性OCs中,它可以达到3-5%。我们报告了一例10岁的女性,她的右肩胛骨后部逐渐肿胀。在过去两年的过程中观察到这种逐渐增长并伴有轻度疼痛。疼痛是间歇性的,不影响她的日常活动。在检查中,一个硬,tender,在右肩胛骨上发现约2×2cm的非活动肿胀。患者的肩部和肩胸区域的活动范围正常。总之,由于孤立的肩胛骨OCs极为罕见,当与HME相关联时,它们是相当常见的。这项研究旨在提高对OC异常位点的认识。此外,我们已经全面介绍了我们对该患者进行的手术治疗,以帮助未来可能遇到类似疾病的外科医生。
    Osteochondromas (OCs) are bone lesions composed of cartilaginous and medullary bone capped with hyaline cartilage. OCs result from the separation of epiphyseal growth plate cartilage, pushing through the periosteal bone cuff. They commonly appear as pedunculated or sessile masses in the metaphysis of long bones and are the most common benign bone tumors. While rare in the scapula, OCs can occur there. Symptoms may arise from fractures, osseous abnormalities, or potential malignant transformation, especially in the presence of hereditary multiple exostoses (HME). The estimated rate of malignant transformation in solitary lesions is 1%, whereas in hereditary multiple OCs, it can reach up to 3-5%. We report a case of a 10-year-old female who presented with a gradually progressive swelling on the back of her right scapula. This progressive growth has been observed over the course of the past two years accompanied by mild pain. The pain was intermittent and did not affect her daily activities. On examination, a hard, tender, non-mobile swelling of approximately 2 × 2 cm was found over the right scapula. The patient had a normal range of motion in the shoulder and scapulothoracic regions. In conclusion, since solitary scapular OCs are extremely rare, they are quite common when associated with HME. This study aimed to increase awareness of the unusual site of OCs. Furthermore, we have included a full account of the surgical therapy we administered to this patient in order to assist future surgeons who may come across similar conditions.
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  • 文章类型: Case Reports
    骨软骨瘤(OCs)是起源于骨膜的发育异常,通常在关节附近的内角骨化过程中形成。由各种囊内外生骨外生形式引起的髌骨后OC,肌腱内,和膝关节内的关节相邻位置。在这种情况下,一名19岁的男性出现肿胀和左膝肿块,这引起了对骨肿瘤的怀疑。在评估X射线图像并进行组织病理学检查后,诊断为髌后OC.
    Osteochondromas (OCs) are developmental anomalies that originate from the periosteum and typically form during enchondral ossification near the joints. Retro-patellar OC caused by exostosis forms in various intracapsular, intra-tendon, and joint-adjacent positions within the knee joint. In this case, a 19-year-old male presented with swelling and a mass in his left knee, which raised suspicion of bone tumors. After evaluating x-ray images and conducting histopathological examinations, the diagnosis was confirmed as retro-patellar OC.
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  • 文章类型: Case Reports
    足和踝关节外生骨非常罕见,目前尚无有关芝麻骨外生骨的文献。
    一名中年妇女被转诊到整形外科足科医生,因为她的左拇指下有一个长期的疼痛的非波动性肿胀,影像学正常。重复X光,可以看到脚的芝麻样,是由于患者的持续症状而进行的。患者接受了手术切除并完全康复。患者现在能够舒适地行走更长的距离,而对她的活动没有限制。
    应初步试验保守管理,以保持足部功能并限制手术并发症的风险。在这种情况下,当探索手术选择时,保留尽可能多的芝麻骨以恢复和维持功能至关重要。
    UNASSIGNED: Exostoses in the foot and ankle are extremely rare with no current literature of exostosis of the sesamoid bone.
    UNASSIGNED: A middle-aged woman was referred to orthopedic foot surgeons following a long-standing issue of a painful non-fluctuant swelling beneath her left hallux with normal imaging. Repeat X-rays, with sesamoid views of the foot, were conducted due to the patient\'s ongoing symptoms. The patient underwent a surgical excision and made a complete recovery. The patient is now able to comfortably walk for longer distances with no restrictions to her mobility.
    UNASSIGNED: Conservative management should be initially trialed to preserve the foot\'s functions and limit the risk of surgical complications. As in this case, when surgical options are explored, it is critical to preserve as much of the sesamoid bone as possible to restore and sustain function.
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  • 文章类型: Case Reports
    骨软骨瘤是骨最常见的良性肿瘤。这些病变主要影响长骨干干meta端,通常无症状。当这些病变出现并发症时,然后他们成为症状和手术切除可能成为指征。骨软骨瘤的自发消退是罕见的。关于这种情况的病例报告较少。我们报告的是16岁,男性,他的肩膀受到直接创伤,并在孤立性骨软骨瘤的底部出现骨折。骨折后18个月,无需任何手术干预即可完全缓解病变。
    Osteochondromas are the most common benign tumors of the bone. Mainly these lesions affect the long-bone metaphysis and usually are asymptomatic. When complications develop from these lesions, then they become symptomatic and surgical resection may become indicated. Spontaneous resolution of osteochondroma is rare. There have been fewer case reports about this condition. We are reporting 16 years old, male, who sustained direct trauma to his shoulder and presented with fracture at the base of a solitary osteochondroma. Complete resolution of the lesion occurred without any surgical intervention 18 months following the fracture.
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  • 文章类型: Journal Article
    骨软骨瘤是一种良性软骨肿瘤,通常起源于长骨的生长板。它在扁平骨头中的表现并不常见。脊柱骨软骨瘤是一种罕见的病例,与所有脊柱肿瘤相比,发病率仅为4%。我们报告了一名15岁患者C4脊柱棘突处骨软骨瘤的不寻常病例,主要主诉是运动时颈部不适。该患者先前已被诊断并治疗其他骨骼的多个遗传性外生骨。患者接受了当前病变的手术,并完全切除了病变的底部。组织病理学显示良性骨软骨瘤,带有一层薄薄的软骨帽。患者治愈顺利,在1年的随访中,同一部位的病变没有复发。手术切除仍然是骨软骨瘤的主要治疗方法,并且已被证明具有低复发率。在宫颈骨软骨瘤的情况下,手术是可取的,特别是在有症状的患者中,预防并发症。
    Osteochondroma is a benign cartilaginous tumor that usually arises from the growth plate of the long bones. Its presentation in flat bones is uncommon. Spinal osteochondroma is a rare case, with only a 4% incidence compared to all spinal neoplasms. We report an unusual case of osteochondroma at the spinous process of the C4 spine of a 15-year-old patient with the chief complaint of neck discomfort on movement. The patient has previously been diagnosed and treated for multiple hereditary exostoses of other bones. The patient underwent surgery for the current lesion with complete excision to the base of the lesion. Histopathology revealed a benign osteochondroma with a thin layer of cartilaginous cap. The patient was healed uneventfully and had no recurrence of the lesion on the same site at the 1-year follow-up. Surgical resection remains the mainstay treatment of osteochondroma and has proved to the low recurrence. In the case of cervical osteochondroma, surgery is advisable, particularly in symptomatic patients, to prevent complications.
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  • 文章类型: Case Reports
    儿童结直肠癌极为罕见,骨软骨瘤病也是如此。这两种疾病在非洲国家都没有流行病学记录。本报告的目的是介绍儿童中罕见的CRC和多个内生瘤共存。
    方法:一例12岁男孩,继发于晚期降结肠肿瘤,出现大肠梗阻。他还被诊断患有累及腿部的多发性骨软骨瘤,武器,肋骨,肩胛骨,锁骨和骨盆.无阳性家族史记录。进行紧急左半结肠切除术和转移横结肠造口术。结肠可作为IIIB期,患者接受辅助化疗。经过8个月的随访,结肠造口术成功逆转,无任何肿瘤生长或远处转移的内镜征象.
    儿童时期的结直肠癌是罕见的。与成人相比,儿童可能具有侵袭性组织学亚型。关于结直肠癌和多发性骨软骨瘤病并存的报道很少或没有。DNA肿瘤中的微卫星不稳定性在结肠癌中很常见,EXT-1和EXT-2基因的各种突变与软骨瘤病有关。
    结论:两种罕见情况的共存是该病例报告中的显着问题。文献中没有先前的报道。可能需要进一步的基因组测序以更好地理解这种共存。
    UNASSIGNED: Childhood colorectal cancers are extremely rare and so is Osteochondromatosis. Both diseases do not have epidemiological records in African countries. The aim of this report is to present a rare coexistence of CRC and multiple enchondromas in a child.
    METHODS: A case of a 12-year-old boy who presented with a large bowel obstruction secondary to an advanced tumor of the descending colon. He was also diagnosed with multiple osteochondromas affecting legs, arms, ribs, scapula, clavicle and pelvis. No positive family history was recorded. An urgent left hemicolectomy and diverting transverse colostomy was done. The colon can as stage IIIB and the patient received adjuvant chemotherapy. After 8 months of follow up, the colostomy was successfully reversed without any endoscopic signs of tumor growth or distant metastasis.
    UNASSIGNED: Colorectal cancer in childhood is rare. It may present with aggressive histological subtypes in children as compared to adults. There is little to no reports on the coexistence of colorectal cancer and multiple Osteochondromatosis. Microsatellite instability in DNA tumor is common in Colon Cancer and variety of mutations of EXT-1 and EXT-2 genes goes with Enchondromatosis.
    CONCLUSIONS: The coexistence of two rare conditions is the remarkable issue in this case report. There are no prior reports in literature. Further genomic sequencing maybe required to better understand this coexistence.
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