Ear, nose and throat

耳朵,鼻子和喉咙
  • 文章类型: Case Reports
    头部慢性皮肤缺陷,面部和颈部对封闭构成挑战,尤其是在多次手术或放射治疗后。我们报告了一名70多岁的女性在鳞状细胞癌切除术后患有慢性枕骨伤口的病例,导致暴露的头骨。尽管有各种选择,我们用Kerecis鱼皮移植(FSG)成功治疗了4cmx5cm的伤口,观察一周内显着改善。FSG促进肉芽组织形成,使得随后从患者的腹股沟进行全厚度皮肤移植。2周内伤口完全闭合,表明FSG在复杂伤口管理中的功效。我们的经验凸显了FSG作为伤口愈合和重建的宝贵工具的潜力,特别是在涉及头部和颈部的挑战性病例中。
    Chronic skin defects in the head, face and neck pose challenges for closure, especially after multiple surgeries or radiation therapy. We report the case of a woman in her 70s with a chronic occipital wound following squamous cell carcinoma resections, resulting in exposed skull bone. Despite various options, we successfully treated the 4 cm x 5 cm wound with a Kerecis fish skin graft (FSG), observing significant improvement within a week. The FSG promoted granulation tissue formation, enabling subsequent full-thickness skin grafting from the patient\'s groin. Complete wound closure was achieved within 2 weeks, indicating FSG\'s efficacy in complex wound management. Our experience highlights FSG\'s potential as a valuable tool in wound healing and reconstruction, particularly in challenging cases involving the head and neck.
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  • 文章类型: Case Reports
    假性动脉瘤是由于动脉壁连续性受损而形成的囊。医源性颈动脉动脉瘤是一种罕见的,细针穿刺(FNA)后危及生命的并发症。我们在此介绍FNA后假性动脉瘤的病例,并进行文献综述。
    Pseudoaneurysm is the formation of a sac due to damage in the continuity of the arterial wall. Iatrogenic carotid artery aneurysm is a rare, life-threatening complication following fine needle aspiration (FNA). We are presenting here a case of pseudoaneurysm following FNA with a literature review.
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  • 文章类型: Case Reports
    一名20多岁的患者出现左眼外观变化,并有相对传入瞳孔缺损的证据。成像显示巨大的额筛骨骨瘤,良性鼻窦肿瘤,侵入四分之三的轨道.涉及眼科学的多学科讨论,颌面外科,神经外科和耳鼻喉科决定尝试完全内镜下切除该病变,结果成功。此病例表明,对于出现眼球突出或其他提示眼眶室受压的眼部体征的患者,在鉴别诊断中应如何考虑鼻窦骨瘤。此病例报告和文献综述强调了通过完全内窥镜入路治疗具有眼眶延伸的巨大鼻窦骨瘤的可能性。
    A patient in his 20s presented with a change in the appearance of his left eye with evidence of relative afferent pupillary defect. Imaging revealed a giant frontoethmoidal osteoma, a benign sinonasal tumour, invading three-quarters of the orbit. Multidisciplinary discussion involving opthalmology, maxillofacial surgery, neurosurgery and otolaryngology resulted in the decision to attempt entirely endoscopic excision of this lesion, which was performed with successful outcomes. This case demonstrates how a sinonasal osteoma should be considered in the differential diagnosis for a patient presenting with proptosis or other eye signs suggestive of compression of the orbital compartment. This case report and literature review highlights the possibility of managing giant sinonasal osteomas with orbital extension through a completely endoscopic approach.
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  • 文章类型: Journal Article
    目标:最近大型语言模型(LLM)的普及激增,比如ChatGPT,展示了他们在体检方面的熟练程度和在医疗保健中的潜在应用。然而,LLM具有固有的局限性,包括不一致的准确性,具体提示要求,以及产生有害幻觉的风险。特定于域的模型可以有效地解决这些限制。
    方法:开发设计。
    方法:虚拟。
    方法:耳鼻咽喉头颈外科(OHNS)相关数据从开放的Internet资源中系统地收集,并编入知识数据库。我们利用检索增强语言建模来回忆这些信息,并将其用于预训练,然后将其集成到ChatGPT4.0中,创建了一个称为ChatENT的OHNS特定知识问答平台。该模型在不同类型的问题上进一步测试。
    结果:ChatENT在分析和解释OHNS信息方面表现增强,ChatGPT4.0在加拿大皇家学院OHNS样本考试试题挑战和美国董事会实践试题挑战中的表现均优于ChatGPT4.0,误差减少了58.4%和26.0%,分别。Chatent产生的幻觉较少,并且表现出更大的一致性。
    结论:据我们所知,ChatENT是医疗领域中第一个利用最新LLM的专业特定知识检索人工智能。它似乎在医学教育等领域有相当大的前景,患者教育,和临床决策支持。该模型证明了克服现有LLM限制的能力,从而预示着更精确的未来,安全,以及OHNS和其他医疗领域的用户友好应用。
    OBJECTIVE: The recent surge in popularity of large language models (LLMs), such as ChatGPT, has showcased their proficiency in medical examinations and potential applications in health care. However, LLMs possess inherent limitations, including inconsistent accuracy, specific prompting requirements, and the risk of generating harmful hallucinations. A domain-specific model might address these limitations effectively.
    METHODS: Developmental design.
    METHODS: Virtual.
    METHODS: Otolaryngology-head and neck surgery (OHNS) relevant data were systematically gathered from open-access Internet sources and indexed into a knowledge database. We leveraged Retrieval-Augmented Language Modeling to recall this information and utilized it for pretraining, which was then integrated into ChatGPT4.0, creating an OHNS-specific knowledge question & answer platform known as ChatENT. The model is further tested on different types of questions.
    RESULTS: ChatENT showed enhanced performance in the analysis and interpretation of OHNS information, outperforming ChatGPT4.0 in both the Canadian Royal College OHNS sample examination questions challenge and the US board practice questions challenge, with a 58.4% and 26.0% error reduction, respectively. ChatENT generated fewer hallucinations and demonstrated greater consistency.
    CONCLUSIONS: To the best of our knowledge, ChatENT is the first specialty-specific knowledge retrieval artificial intelligence in the medical field that utilizes the latest LLM. It appears to have considerable promise in areas such as medical education, patient education, and clinical decision support. The model has demonstrated the capacity to overcome the limitations of existing LLMs, thereby signaling a future of more precise, safe, and user-friendly applications in the realm of OHNS and other medical fields.
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  • 文章类型: Case Reports
    暂无摘要。
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  • 文章类型: Case Reports
    Goldenhar综合征,也被认为是眼-耳-椎骨光谱,是一种非常罕见的疾病,以影响眼部的各种临床异常为特征,听觉,脊椎和各种器官系统。由于其固有的遗传变异性和稀有性,这种疾病的病理生理学尚未完全阐明。在这份报告中,我们介绍了一个蹒跚学步的男孩的Goldenhar综合征,旨在在这种情况下增强现有的文学主体。
    Goldenhar syndrome, also recognised as oculo-auriculo-vertebral spectrum, is a very rare condition distinguished by a diverse array of clinical abnormalities affecting the ocular, auditory, vertebral and various organ systems. The pathophysiology of this condition is not fully elucidated due to its inherent genetic variability and rarity. In this report, we present a case of Goldenhar syndrome in a toddler boy, aiming to enhance the existing body of literature on this condition.
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  • 文章类型: Case Reports
    在免疫功能低下的患者和糖尿病患者中,颅底骨髓炎可能更危及生命。这里,我们介绍了一例50多岁的糖尿病男性,由颅底骨髓炎引起的颈内动脉假性动脉瘤。该病例报告强调需要意识到与颅底骨髓炎相关的各种并发症,精通检测它们,并尽早治疗它们以获得更好的结果。在通过药物治疗充分控制疾病过程后,采用球囊血管成形术和支架置入术对动脉瘤进行即时处理.承认轻微的鼻和耳出血,在诊断为颅底骨髓炎的病例中,放射学评估是必要的,以排除罕见的并发症,如假性动脉瘤。在讨论中,我们列举了骨髓炎引起假性动脉瘤的各种治疗方法和类似病例。目前,患者继续过着疾病和无残疾的生活。
    Skull base osteomyelitis can be more life-threatening in immunocompromised patients and patients with diabetes. Here, we present a case of a petrous internal carotid artery pseudoaneurysm resulting from skull base osteomyelitis in a diabetic male in his 50s. This case report highlights the need to be conscious of the various complications associated with skull base osteomyelitis, be proficient in detecting them and treat them as early as possible for better outcomes. After adequate control of the disease process with medical treatment, immediate management of the aneurysm with balloon angioplasty and stenting was done. Acknowledging the trivial nasal and ear bleed, radiological evaluation is necessary to rule out rare complications like pseudoaneurysms in a diagnosed case of skull base osteomyelitis. In the discussion, we have cited the various treatment methods and similar cases of pseudoaneurysm caused by osteomyelitis. Currently, the patient continues to live a disease and disability-free life.
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  • 文章类型: Case Reports
    文献中很少记录自发性脑膜脑囊肿(MEC)。发生在额窦的那些是非常罕见的实体。MECs通常与脑脊液(CSF)鼻漏有关。脑脊液鼻漏常被误诊,导致诊断和管理延误。随后增加的细菌性脑膜炎的风险可能危及患者的生命。我们报道了一个70多岁的女性患有自发性额窦MEC的病例,有6个月的脑脊液鼻漏病史。该患者使用新型Carolyn窗内窥镜成功治疗;9个月的随访未发现颅底破裂。我们的案例强调了将MEC作为明确鼻漏的鉴别诊断的重要性,并通过新颖的手术方法证明了成功的修复。
    Spontaneous meningoencephaloceles (MECs) are sparsely documented in the literature. Those occurring in the frontal sinus are an exceedingly rare entity. MECs are commonly associated with cerebrospinal fluid (CSF) rhinorrhoea. CSF rhinorrhoea is frequently misdiagnosed, causing delays in diagnosis and management. The subsequently increased risk of bacterial meningitis can be life-threatening to patients. We report the case of a woman in her late 70s with a spontaneous frontal sinus MEC, presenting with a 6-month history of CSF rhinorrhoea. The patient was successfully treated using the novel Carolyn\'s window approach endoscopically; 9-month follow-up revealed no skull-base breach. Our case emphasises the importance of considering MEC as a differential diagnosis for clear rhinorrhoea and demonstrates successful repair through a novel surgical approach.
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  • 文章类型: Case Reports
    颅颌面外伤主要由口腔颌面外科医生诊断和管理。在遇到的案件中,涉及眶壁的中面骨折非常普遍。在这些骨折中,轨道壁的参与,特别是轨道的地板,会导致相当大的美学和功能限制。从颌面部的角度来看,眼眶底手术修复的适应症包括眼动力明显下降,影响50%以上表面积的断裂,眼眶体积增加超过18%,眼球内陷大于2毫米。如果没有这些明显的迹象,通常不需要手术干预。然而,在这种情况下,8个月前有中面外伤和轻微眶底骨折病史的早期青少年表现为渐进性延迟性眼球内陷和眼球下移,与无症状窦综合征的特征非常相似.通过在眶底放置定制的不可吸收的高密度聚乙烯植入物来矫正眼球内陷和下眼球。术后随访显示美学和功能令人满意的结果。
    Craniomaxillofacial trauma is primarily diagnosed and managed by oral and maxillofacial surgeons. Among the cases encountered, midface fractures involving orbital walls are highly prevalent. In these fractures, involvement of the orbital walls, particularly floor of the orbit, can lead to considerable aesthetic and functional limitations. From a maxillofacial perspective, indications for surgical repair of orbital floor encompass marked decrease in ocular motility, fracture affecting more than 50% of surface area, an increase in orbital volume exceeding 18% and enophthalmos greater than 2 mm. In the absence of these discernible signs, surgical intervention is not generally indicated. However, in this case, an early adolescent with a history of midface trauma and minimal orbital floor fracture 8 months earlier presented with progressively delayed onset enophthalmos and hypoglobus closely resembling features of silent sinus syndrome. The enophthalmos and hypoglobus were corrected by placing custom-made non-resorbable high-density polyethylene implant in the orbital floor. Postoperative follow-up demonstrated aesthetically and functionally satisfactory outcomes.
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  • 文章类型: Case Reports
    在过去的6年中,一名20多岁的男子抱怨单侧鼻塞,这种情况逐渐恶化,导致不合理地使用非处方鼻减充血剂。随着症状的恶化,进行了非造影CT检查.它显示了右下鼻甲的致密的扩张性硬化病变,是用内窥镜切除的。下鼻甲的骨化性纤维瘤很少见,需要评估和手术切除以减轻鼻塞的症状。它的名称来自其中存在的纤维和矿化组织的可变比例,并且仅在颅面区域发展。它可以通过内窥镜手术管理,鼻内非内镜(带镜)或开放入路(鼻侧切开术,阴唇下入路或面部中部脱皮)。这里,我们介绍了如何通过内窥镜方法检测和手术治疗这种情况,这是一种微创选择,住院时间短,恢复早。
    A man in his 20s presented with complaints of unilateral nasal obstruction for the past 6 years that progressively worsened leading to irrational use of over-the-counter nasal decongestants. With the worsening of symptoms, a non-contrast CT was done. It showed a dense expansile sclerotic lesion of the right inferior turbinate, which was excised endoscopically. Cemento-ossifying fibromas of the inferior turbinate are rare and require assessment and surgical excision to relieve the symptom of nasal obstruction. It derives its name from the variable proportions of fibrous and mineralised tissue present in it and exclusively develops in the craniofacial region. It can be surgically managed by an endoscopic, an endonasal non-endoscopic (with a speculum) or an open approach (lateral rhinotomy, sublabial approach or mid-facial degloving). Here, we present how such a case was detected and managed surgically by the endoscopic approach, which is a minimally invasive option with shorter hospital stay and early recovery.
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