%0 Case Reports %T Resolution of a chronic occipital wound with exposed skull bone with a fish skin graft: a successful treatment approach. %A Veitinger AB %A Lippert BM %A Fiedler LS %J BMJ Case Rep %V 17 %N 8 %D 2024 Aug 3 %M 39097322 暂无%R 10.1136/bcr-2024-261172 %X Chronic skin defects in the head, face and neck pose challenges for closure, especially after multiple surgeries or radiation therapy. We report the case of a woman in her 70s with a chronic occipital wound following squamous cell carcinoma resections, resulting in exposed skull bone. Despite various options, we successfully treated the 4 cm x 5 cm wound with a Kerecis fish skin graft (FSG), observing significant improvement within a week. The FSG promoted granulation tissue formation, enabling subsequent full-thickness skin grafting from the patient's groin. Complete wound closure was achieved within 2 weeks, indicating FSG's efficacy in complex wound management. Our experience highlights FSG's potential as a valuable tool in wound healing and reconstruction, particularly in challenging cases involving the head and neck.