未经评估:本研究旨在确定咽鼓管球囊扩张(ETBD)治疗反应的临床预测因子,通过咽鼓管功能障碍问卷-7(ETDQ-7)评分的变化来衡量。
UNASSIGNED:从2017年到2021年,在一家机构接受ETBD的13名患者在手术前后完成了ETDQ-7。我们用ETDQ-7归一化(术后<2.1)进行了多变量回归分析,最小临床重要差异(MCID)(>0.5术前-术后),ETDQ-7评分的定量改善作为结果变量。术前ETDQ-7评分,鼓室图类型,慢性中耳炎,慢性鼻-鼻窦炎(CRS),下鼻甲肥大,隔膜偏斜,过敏性鼻炎,鼻漏作为协变量。模型控制年龄,性别,种族,之前的耳朵或鼻窦手术,和后续持续时间。
未经证实:平均年龄49岁。51%是女性,所有患者术前ETDQ-7均高于2.1。经过13个月的平均随访,77%实现了MCID,37%实现了正常化。术前较高的ETDQ-7评分与较高的ETDQ-7评分改善相关(B=0.60,95%CI=[0.37,0.83])和较高的实现MCID的几率相关(aOR=1.65;95%CI=[1.06,2.59])。CRS病史提高了达到MCID的机会(aOR=4.53;95%CI=[1.11,18.55]),慢性中耳炎病史预测ETDQ-7正常化的几率增加(aOR=2.88;95%CI=[1.09,7.58])。
未经批准:我们的研究结果表明,ETBD在ETDQ-7高于2.1的患者中非常有效。此外,术前ETDQ-7评分较高,CRS,和慢性中耳炎预测更有利的症状受益于ETBD。在为该程序的潜在候选人提供咨询时,考虑这些因素可能很重要。
UNASSIGNED: This study aims to identify clinical predictors of treatment response to Eustachian Tube Balloon Dilation (ETBD) as measured by changes in Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7) scores.
UNASSIGNED: One hundred thirteen patients who underwent ETBD at an institution from 2017 to 2021 completed ETDQ-7 pre- and post-operatively. We conducted multivariable regression analyses with ETDQ-7 normalization (<2.1 post-op), minimum clinically important difference (MCID) (>0.5 pre-op - post-op), and quantitative improvement in ETDQ-7 score as outcome variables. Pre-operative ETDQ-7 score, tympanogram type, chronic otitis media, chronic rhinosinusitis (CRS), inferior turbinate hypertrophy, deviated septum, allergic rhinitis, and rhinorrhea were included as covariates. Models controlled for age, sex, ethnicity, prior ear or sinus surgery, and follow-up duration.
UNASSIGNED: The mean age was 49 years old. 51% were females, and all patients had pre-operative ETDQ-7 above 2.1. After a mean follow-up period of 13 months, 77% achieved MCID and 37% had normalized. Higher pre-operative ETDQ-7 score was associated with greater ETDQ-7 score improvement (B = 0.60, 95% CI = [0.37, 0.83]) and greater odds of achieving MCID (aOR = 1.65; 95% CI = [1.06, 2.59]). A history of CRS improved chances of achieving MCID (aOR = 4.53; 95% CI = [1.11, 18.55]) and a history of chronic otitis media predicted increased odds of ETDQ-7 normalization (aOR = 2.88; 95% CI = [1.09, 7.58]).
UNASSIGNED: Our findings suggest that ETBD was highly effective among patients with pre-operative ETDQ-7 above 2.1. Furthermore, higher pre-operative ETDQ-7 score, CRS, and chronic otitis media predicted more favorable symptomatic benefit from ETBD. These factors may be important to consider when counseling potential candidates for this procedure.