■本文旨在评估三维超声(3DUS)的诊断性能和临床价值,三维超声能量多普勒(3DPD),和3DUS联合3DPD在卵巢癌(OC)中的应用。
■该研究已在PROSPERO注册(CRD42023405765)。从开始到2022年1月25日搜索PubMed和WebofScience,并手动搜索可能符合条件的研究的参考列表。患者和研究特征由两名独立的审阅者提取。通过讨论解决了任何差异。敏感性,特异性,正负似然比(PLR和NLR,分别),和受试者工作特征曲线下面积(AUC)分别合并。
■我们检索了2,566项研究,其中18人最终被录取,2,548例。汇集的敏感性,特异性,PLR,NLR,3DUS的AUC为0.89(95%CI:0.85-0.93),0.93(95%CI:0.88-0.96),13.1(95%CI:7.3-23.4),0.11(95%CI:0.08-0.16),和0.90(95%CI:0.87-0.93),分别。汇集的敏感性,特异性,PLR,NLR,3DPD的AUC为0.90(95%CI:0.80-0.95),0.85(95%CI:0.71-0.92),5.8(95%CI:3.0-11.2),0.12(95%CI:0.06-0.24),和0.94(95%CI:0.91-0.96),分别。汇集的敏感性,特异性,PLR,NLR,3DUS联合3DPD的AUC为0.99(95%CI:0.73-1.00),0.95(95%CI:0.85-0.99),21.9(95%CI:6.1-78.9),0.01(95%CI:0.00-0.37),和0.99(95%CI:0.98-1.00),分别。
■3DUS,3DPD,3DUS与3DPD相结合是有前途的OC诊断工具,除了提高的敏感性和特异性。然而,3DUS和3DPD技术的结合具有较高的诊断效率。
■https://www.crd.约克。AC.英国/PROSPERO/,标识符CRD42023405765。
UNASSIGNED: This paper was to assess the diagnostic performance and clinical value of three-dimensional ultrasonography (3DUS), three-dimensional ultrasonography power Doppler (3DPD), and 3DUS combined with 3DPD in ovarian cancer (OC).
UNASSIGNED: The study was registered with PROSPERO (CRD 42023405765). PubMed and Web of Science were searched from inception to 25 January 2022, and reference lists of potentially eligible studies were also manually searched. Patient and study characteristics were extracted by two independent reviewers. Any discrepancies were addressed through discussion. The sensitivity, specificity, positive and negative likelihood ratio (PLR and NLR, respectively), and the area under the receiver operating characteristic curve (AUC) were pooled separately.
UNASSIGNED: We retrieved 2,566 studies, of which 18 were finally enrolled, with 2,548 cases. The pooled sensitivity, specificity, PLR, NLR, and AUC for 3DUS were 0.89 (95% CI: 0.85-0.93), 0.93 (95% CI: 0.88-0.96), 13.1 (95% CI: 7.3-23.4), 0.11 (95% CI: 0.08-0.16), and 0.90 (95% CI: 0.87-0.93), respectively. The pooled sensitivity, specificity, PLR, NLR, and AUC for 3DPD were 0.90 (95% CI: 0.80-0.95), 0.85 (95% CI: 0.71-0.92), 5.8 (95% CI: 3.0-11.2), 0.12 (95% CI: 0.06-0.24), and 0.94 (95% CI: 0.91-0.96), respectively. The pooled sensitivity, specificity, PLR, NLR, and AUC for 3DUS combined with 3DPD were 0.99 (95% CI: 0.73-1.00), 0.95 (95% CI: 0.85-0.99), 21.9 (95% CI: 6.1-78.9), 0.01 (95% CI: 0.00-0.37), and 0.99 (95% CI: 0.98-1.00), respectively.
UNASSIGNED: 3DUS, 3DPD, and 3DUS combined with 3DPD are promising diagnostic tools for OC, alongside elevated sensitivity and specificity. However, the combination of 3DUS and 3DPD techniques has higher diagnostic efficiency.
UNASSIGNED: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD 42023405765.