Dermatologic surgery

皮肤病外科
  • 文章类型: Journal Article
    背景:人工智能(AI)和大型语言模型(LLM)改变了患者告知自己的方式。LLM提供潜在的教育工具,但是它们的质量取决于所产生的信息。当前研究人工智能作为皮肤病学信息工具的文献在评估人工智能的多方面角色和意见多样性方面受到限制。这里,我们利用国际专家小组评估LLM作为临床内外Mohs显微外科手术(MMS)的患者教育工具.
    方法:从Google中提取最常见的患者彩信问题,并将其转换为两个LLM和Google的搜索引擎。15名MMS外科医生评估了产生的反应,检查它们作为面向患者的信息平台的适当性,在临床环境中反应充足,和生成内容的准确性。采用验证的量表来评估每个反应的可理解性。
    结果:大多数审稿人认为所有LLM回答都是合适的。75%的反应被评为大多数准确或更高。ChatGPT的平均准确度最高。大多数小组认为33%的反应足以用于临床实践。所有平台的平均可理解性分数表示所需的10年级阅读水平。
    结论:LLM产生的反应被评为适当的患者信息源,其内容大多准确。然而,这些平台可能无法提供足够的信息来在临床环境中运行,复杂的可理解性可能是利用的障碍。随着这些平台的普及,皮肤科医生必须意识到这些局限性。
    Artificial intelligence (AI) and large language models (LLMs) transform how patients inform themselves. LLMs offer potential as educational tools, but their quality depends upon the information generated. Current literature examining AI as an informational tool in dermatology has been limited in evaluating AI\'s multifaceted roles and diversity of opinions. Here, we evaluate LLMs as a patient-educational tool for Mohs micrographic surgery (MMS) in and out of the clinic utilizing an international expert panel.
    The most common patient MMS questions were extracted from Google and transposed into two LLMs and Google\'s search engine. 15 MMS surgeons evaluated the generated responses, examining their appropriateness as a patient-facing informational platform, sufficiency of response in a clinical environment, and accuracy of content generated. Validated scales were employed to assess the comprehensibility of each response.
    The majority of reviewers deemed all LLM responses appropriate. 75% of responses were rated as mostly accurate or higher. ChatGPT had the highest mean accuracy. The majority of the panel deemed 33% of responses sufficient for clinical practice. The mean comprehensibility scores for all platforms indicated a required 10th-grade reading level.
    LLM-generated responses were rated as appropriate patient informational sources and mostly accurate in their content. However, these platforms may not provide sufficient information to function in a clinical environment, and complex comprehensibility may represent a barrier to utilization. As the popularity of these platforms increases, it is important for dermatologists to be aware of these limitations.
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  • 文章类型: Journal Article
    由于不可逆的毛囊损伤,瘢痕性脱发(CA)对皮肤科医生构成了挑战。虽然药物治疗提供有限的疗效,手术干预旨在改善美学效果。本文探讨了连续切除技术(SET)作为稳定的炎症性CA病例的可行选择。
    三名患有不同形式CA的成年女性接受了分阶段手术以纠正CA斑块。手术包括根据年龄等个人特征采用不同的切口和闭合方法,脱发的类型和程度,location,疤痕区域的组织活动性。
    CA显著影响患者的生活质量,需要综合治疗方法。SET成为稳定病例的令人鼓舞的可能性,提供显著的美容改善和提高患者的健康。这种技术具有潜在的独立疗效或与毛发移植相结合的成本效益。为CA患者提供有希望的结果。
    UNASSIGNED: Cicatricial alopecia (CA) poses a challenge for dermatologists due to irreversible hair follicle damage. While pharmacological treatments offer limited efficacy, surgical interventions aim to improve aesthetic outcomes. This article explores the serial excision technique (SET) as a viable option for stable cases of inflammatory CA.
    UNASSIGNED: Three adult females with different forms of CA underwent staged surgeries to correct CA patches. Procedures included different incision and closure methods based on individual characteristics such as age, type and extent of alopecia, location, and tissue mobility in the scarred area.
    UNASSIGNED: CA significantly impacts patients\' quality of life, demanding comprehensive treatment approaches. SET emerges as an encouraging possibility for stable cases, providing notable cosmetic improvements and enhancing patients\' well-being. This technique offers cost-effective benefits with potential standalone efficacy or in combination with hair transplantation, providing promising outcomes for individuals with CA.
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  • 文章类型: Journal Article
    指甲血管球瘤是一种众所周知的肿瘤,具有明确的临床特征和手术治疗;然而,其中一些病变发生在不同的位置和大小,手术很难解决。
    临床和影像学检查有助于肿瘤的诊断和定位。
    对这些病例有足够的外科知识可确保较低的复发率和指甲营养不良。
    UNASSIGNED: Nail glomus tumor is a well-known tumor, with well-defined clinical characteristics and surgical treatment; however, some of these lesions occur in different locations and sizes with difficult surgical resolution.
    UNASSIGNED: Clinical and imaging tests help in the diagnosis and tumor localization.
    UNASSIGNED: Adequate surgical knowledge for these cases ensures lower rates of recurrence and nail dystrophy.
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  • 文章类型: Journal Article
    UNASSIGNED: Dermatochirurgische Eingriffe finden überwiegend in Lokalanästhesie statt, jedoch gibt es nur wenig Studien zum perioperativen Schmerzmanagement ausgedehnter oder mehrzeitiger Operationen. Das Ziel dieser Erhebung ist die Erfassung von Schmerzen im Rahmen dermatochirurgischer Eingriffe, der Darstellung der perioperativen Schmerztherapie sowie der Identifizierung von Einflussfaktoren auf das Schmerzempfinden.
    UNASSIGNED: In diese prospektive, monozentrische Studie wurden stationäre Patienten von April bis Dezember 2021 eingeschlossen, die einen dermatochirurgischen Eingriff in Lokalanästhesie erhielten. Präoperativ wurden demographische Fragen, ein Schmerzfragebogen und vier psychometrische Fragebögen (PCS, LOT‐R, SFQ, PHQ‐9) erhoben. Postoperativ empfundene Schmerzen und benötigte Schmerzmedikamente der ersten 24 Stunden wurden erhoben.
    UNASSIGNED: 120 Patienten (mit insgesamt 191 Eingriffen) wurden eingeschlossen. Durchschnittliche postoperative Schmerzen wurden sehr niedrig (NRS < 2) angegeben. Präoperativ bestehende Schmerzen und postoperativ erwartete Schmerzen zeigten sich als prädiktive Merkmale für postoperativen Schmerz. Ein starker Zusammenhang zwischen Katastrophisieren und Angst vor der Operation (r = 0,65) sowie ein mittlerer Zusammenhang für Depression und Angst vor der Operation (r = 0,46) konnten dargestellt werden.
    UNASSIGNED: Dermatochirurgische Eingriffe in Lokalanästhesie werden insgesamt als schmerzarm empfunden. Bei der präoperativen Aufklärung und Untersuchung sollte auf Patienten geachtet werden, die bereits Schmerzen angeben oder postoperativ Schmerzen erwarten, da sie ein erhöhtes Risiko für die Entwicklung postoperativer Schmerzen zeigten.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Journal Article
    多形性真皮肉瘤可能具有临床侵袭性,导致局部复发的趋势更高,转移,和死亡。非典型纤维黄色瘤和多形性真皮肉瘤在组织病理学上相似,它们的区别需要对整个切除的肿瘤进行系统检查。由于Mohs显微手术通常用于治疗非典型纤维黄色瘤,通过永久性病理学对debulk标本进行组织病理学评估是谨慎的,以避免对多形性真皮肉瘤的诊断不足。这种方法可以改善风险评估和治疗决策,最终提高患者的治疗效果。此外,适当的区分将有助于未来制定准确的分期标准和其他治疗方式。
    Pleomorphic dermal sarcomas can be clinically aggressive, with a higher tendency to cause local recurrence, metastasis, and death. Atypical fibroxanthoma and pleomorphic dermal sarcoma are histopathologically similar, and their distinction requires a systematic examination of the entire excised tumor. Since Mohs micrographic surgery is commonly utilized to treat atypical fibroxanthoma, a histopathologic evaluation of debulk specimens by permanent pathology is prudent to avoid underdiagnosing pleomorphic dermal sarcoma. This approach can improve risk assessment and treatment decisions, ultimately enhancing patient outcomes. Also, the proper distinction will facilitate the future development of accurate staging criteria and additional treatment modalities.
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  • 文章类型: Case Reports
    毛细胞癌(TBC)是一种罕见的滤泡生殖细胞分化的附件肿瘤,具有局部侵袭和转移的潜力。毛囊母细胞癌的组织学特征与毛囊母细胞瘤和基底细胞癌(BCC)有显著重叠,在某些情况下使诊断变得困难。治疗策略尚不明确,包括局部肿瘤的手术切除和转移性疾病的全身治疗。我们介绍了一例临床上类似于良性囊肿的毛母细胞癌,最终通过Mohs显微手术(MMS)治疗。
    Trichoblastic carcinoma (TBC) is a rare adnexal neoplasm of follicular germ cell differentiation with the potential for local invasion and metastasis. Histologic features of trichoblastic carcinoma have significant overlap with trichoblastoma and basal cell carcinoma (BCC), making diagnosis difficult in some cases. Treatment strategies are not well defined and include surgical excision for localized tumors and systemic therapies for metastatic disease. We present a case of trichoblastic carcinoma clinically resembling a benign cyst that was ultimately treated with Mohs micrographic surgery (MMS).
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  • 文章类型: Journal Article
    背景:患者通常被建议在24至72小时内保持最初的术后敷料干燥且不受干扰。然而,这些要求可能会导致患者日常生活活动的严重中断,比如洗澡,休闲,和锻炼。
    目的:比较保持伤口干燥和覆盖(48小时)与术后早期(6小时)水暴露的标准管理方法:研究者盲,随机化(1:1),对照试验评估感染率和其他感兴趣的结果。
    结果:总体而言,437名患者随机分为早期(6小时)水暴露(n=218)干预组或标准队列(n=219)。干预组培养证实的感染发生率(1.8%)与标准组(1.4%)相似(p>0.99)。出血或瘀伤的发生率也没有差异。使用患者和观察者疤痕评估量表(POSAS)进行的疤痕评估显示出相似的疤痕结果。
    结论:单站点,学术中心。
    结论:手术伤口可以在术后即刻湿润,不会增加感染或其他并发症的发生率,并且具有相似的外观。
    BACKGROUND: Patients are often advised to keep the initial postoperative dressings dry and undisturbed for 24 to 72 hours. However, these requirements may result in significant disruption of patients\' activities of daily living, such as bathing, leisure, and exercise.
    OBJECTIVE: Compare standard management of keeping wounds dry and covered (48 hours) with early (6 hours) postoperative water exposure.
    METHODS: Investigator-blinded, randomized (1:1), controlled trial evaluating rate of infection and additional outcomes of interest.
    RESULTS: Overall, 437 patients were randomized to either the early (6-hour) water exposure (n = 218) intervention group or the standard cohort (n = 219). The incidence of culture-proven infection in the intervention group (1.8%) was similar to the standard group (1.4%) (P > .99). There was also no difference in rates of bleeding or bruising. Scar assessment using the Patient and Observer Scar Assessment Scale revealed similar scar outcomes.
    CONCLUSIONS: Single site, academic center.
    CONCLUSIONS: Surgical wounds can be allowed to get wet in the immediate postoperative period with no increased incidence of infection or other complications and with similar cosmesis.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    背景:皮肤外科手术主要在局部麻醉下进行,然而,很少有研究在局部麻醉下进行广泛或分阶段手术的围手术期疼痛管理。这项研究的目的是评估皮肤科手术期间的疼痛,描述围手术期疼痛管理,并确定影响疼痛感知的因素。
    方法:这种前瞻性,单中心研究纳入了2021年4月至12月在局部麻醉下接受皮肤科手术的住院患者.术前人口统计学数据,一份疼痛问卷,和四个心理测量问卷(PCS,LOT-R,SFQ,收集PHQ-9)。记录前24小时的术后疼痛和镇痛药使用情况。
    结果:共120例患者(共191例干预)被纳入研究。据报道,平均术后疼痛非常低(NRS<2)。发现术前疼痛和预期的术后疼痛可预测术后疼痛。灾难化和术前焦虑之间有很强的相关性(r=0.65),抑郁和术前焦虑之间有中等相关性(r=0.46)。
    结论:局部麻醉下的皮肤手术通常被认为是无痛的。在术前咨询和评估期间,应该注意害怕手术的患者,报告疼痛,或者预测术后疼痛,因为他们经历术后疼痛的风险增加。
    BACKGROUND: Dermatosurgical procedures are predominantly performed under local anesthesia, yet there are few studies on perioperative pain management for extensive or staged procedures under local anesthesia. The purpose of this study was to assess pain during dermatologic surgery, describe perioperative pain management, and identify factors that influence pain perception.
    METHODS: This prospective, monocentric study included inpatients undergoing dermatologic surgery under local anesthesia from April to December 2021. Preoperative demographic data, a pain questionnaire, and four psychometric questionnaires (PCS, LOT-R, SFQ, PHQ-9) were collected. Postoperative pain and analgesic use during the first 24 hours were recorded.
    RESULTS: A total of 120 patients (with a total of 191 interventions) were included in the study. Mean postoperative pain was reported to be very low (NRS < 2). Preoperative pain and expected postoperative pain were found to be predictive of postoperative pain. There was a strong correlation between catastrophizing and preoperative anxiety (r = 0.65) and a moderate correlation between depression and preoperative anxiety (r = 0.46).
    CONCLUSIONS: Dermatologic surgery under local anesthesia is generally considered painless. During preoperative counseling and assessment, attention should be paid to patients who fear surgery, report pain, or anticipate postoperative pain, as they have an increased risk of experiencing postoperative pain.
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