目的:评估树脂浸润在改善磨牙切牙低矿化(MIH)影响的前牙美学外观中的有效性。
方法:PubMed,Scopus,EMBASE,WebofScience,ScienceDirect,从2009年到2024年,搜索了Cochrane中央对照试验登记册(CENTRAL)。该方案已在国际前瞻性系统评价数据库(PROSPEROCRD42023461909)中注册。
方法:包括比较树脂浸润和其他治疗方法在MIH受累前牙的介入或比较研究。使用非随机干预研究中的偏倚风险(ROBINS-I工具)和偏倚风险2(RoB2.0)工具评估偏倚风险。Meta分析采用随机效应模型。
方法:18项研究符合纳入标准,12例纳入荟萃分析.树脂渗透显示治疗前后较高的色差(ΔE)(平均差2.21,95%置信区间[CI]0.04-4.38,p<.001,I2=98.61%,p<.001)和更好的光学改善(标准化平均差[SMD]2.68;95CI0.30-5.06;p=0.027,I2=97.8%,p<.001)与对照相比。基于牙医评估的估计成功率为92%(95CI88-95%,I2=17.92%,p=.06)。非随机试验显示高(8/14)或中等(6/14)的偏倚风险,主要来自混淆和选择问题。由于数据缺失,随机试验具有高风险(1/3)或一些担忧(2/3)。
结论:研究结果表明,树脂浸润可显著改善MIH受累前牙的美学效果,如与对照相比更高的色差和光学改善所证明的。
结论:虽然我们的研究显示了树脂渗透的有希望的结果,包括高成功率和美学改进,需要更大规模的研究和更长的随访时间来证实这些发现并评估其长期疗效.
OBJECTIVE: To evaluate the effectiveness of resin infiltration in improving the aesthetic appearance of anterior teeth affected by molar-incisor hypomineralisation (MIH).
METHODS: PubMed, Scopus, EMBASE, Web of Science, ScienceDirect, and Cochrane Central Register of Controlled Trials (CENTRAL) were searched from 2009 to 2024. The protocol was registered in the International Prospective Database of Systematic Reviews (PROSPERO CRD42023461909).
METHODS: Interventional or comparative studies comparing resin infiltration and other treatments in MIH-affected anterior teeth were included. The risk of bias was evaluated using the Risk Of Bias In Non-randomised Studies of Interventions (ROBINS-I tool) and the Risk of Bias 2 (RoB 2.0) tool. Meta-analysis utilized a random-effects model.
METHODS: Eighteen studies met the inclusion criteria, and twelve were included in the meta-analysis. Resin infiltration showed a higher color difference (ΔE) before and after treatment (mean difference 2.21, 95 % confidence interval [CI] 0.04-4.38, p < 0.001, I2 = 98.61 %, p < 0.001) and better optical improvement (standardised mean difference [SMD] 2.68; 95 %CI 0.30-5.06; p = 0.027, I2 = 97.8 %, p < 0.001) compared to controls. The estimated success rate based on dentist assessment was 92 % (95 %CI 88-95 %, I2 = 17.92 %, p = 0.06). Non-randomised trials showed high (8/14) or moderate (6/14) risk of bias, mainly from confounding and selection issues. Randomised trials had high risk (1/3) or some concerns (2/3) due to missing data.
CONCLUSIONS: The findings suggest that resin infiltration significantly improves aesthetic outcomes in MIH-affected anterior teeth, as evidenced by higher colour difference and optical improvement compared to controls.
CONCLUSIONS: While our study shows promising results for resin infiltration, including high success rates and aesthetic improvements, larger-scale studies with longer follow-up periods are necessary to confirm these findings and assess its long-term efficacy.