PDF(Pubmed)
Abstract：
OBJECTIVE: Familial isolated hypoparathyroidism is a rare genetic disorder due to no or low production of the parathyroid hormone, disturbing calcium and phosphate regulation. The resulting hypocalcemia may lead to dental abnormalities, such as enamel hypoplasia. The aim of this paper was to describe the full-mouth rehabilitation of a 15-year-old girl with chronic hypocalcemia due to a rare congenital hypoparathyroidism.
METHODS: In this patient, in the young adult dentition, conservative care was preferred. Onlays or stainless-steel crowns were performed on the posterior teeth, and direct or indirect (overlays and veneerlays) were performed on the maxillary premolars, canines, and incisors, using a digital wax-up. The mandibular incisors were bleached. The treatment clearly improved the patient\'s oral quality of life, with fewer sensitivities, better chewing, and aesthetic satisfaction. The difficulties were the regular monitoring and the limited compliance of the patient.
CONCLUSIONS: Despite no clinical feedback in the literature, generalized hypomineralized/hypoplastic teeth due to hypoparathyroidism in a young patient can be treated as amelogenesis imperfecta (generalized enamel defects) with a conservative approach for medium-term satisfactory results.
CONCLUSIONS: This study provides new insights into the management of enamel hypoplasia caused by familial isolated hypoparathyroidism, helping to improve patient outcomes in similar cases.
METHODS: In this patient, in the young adult dentition, conservative care was preferred. Onlays or stainless-steel crowns were performed on the posterior teeth, and direct or indirect (overlays and veneerlays) were performed on the maxillary premolars, canines, and incisors, using a digital wax-up. The mandibular incisors were bleached. The treatment clearly improved the patient\'s oral quality of life, with fewer sensitivities, better chewing, and aesthetic satisfaction. The difficulties were the regular monitoring and the limited compliance of the patient.
CONCLUSIONS: Despite no clinical feedback in the literature, generalized hypomineralized/hypoplastic teeth due to hypoparathyroidism in a young patient can be treated as amelogenesis imperfecta (generalized enamel defects) with a conservative approach for medium-term satisfactory results.
CONCLUSIONS: This study provides new insights into the management of enamel hypoplasia caused by familial isolated hypoparathyroidism, helping to improve patient outcomes in similar cases.
摘要：
目的：家族性孤立性甲状旁腺功能减退症是一种罕见的遗传性疾病，原因是甲状旁腺激素不产生或产生量低，干扰钙和磷酸盐的调节。由此产生的低钙血症可能导致牙齿异常，如牙釉质发育不全。本文的目的是描述一名因罕见的先天性甲状旁腺功能减退症而患有慢性低钙血症的15岁女孩的全口康复。
方法：在该患者中，在年轻的成年牙列中，保守护理是首选。在后牙上进行了镶嵌或不锈钢冠，在上颌前磨牙上进行直接或间接（覆盖和贴面），犬科动物,和门牙，使用数字蜡。下颌切牙被漂白。治疗明显改善了患者的口腔生活质量,敏感性较低，更好的咀嚼，和审美满意度。困难在于定期监测和患者的依从性有限。
结论：尽管文献中没有临床反馈，年轻患者甲状旁腺功能减退症引起的全身性低矿化/发育不良牙齿可作为牙釉质发育不全（全身性釉质缺损）进行保守治疗，中期效果满意。
结论：这项研究为家族性孤立性甲状旁腺功能减退症引起的釉质发育不全的治疗提供了新的见解，有助于改善类似病例的患者预后。
方法：在该患者中，在年轻的成年牙列中，保守护理是首选。在后牙上进行了镶嵌或不锈钢冠，在上颌前磨牙上进行直接或间接（覆盖和贴面），犬科动物,和门牙，使用数字蜡。下颌切牙被漂白。治疗明显改善了患者的口腔生活质量,敏感性较低，更好的咀嚼，和审美满意度。困难在于定期监测和患者的依从性有限。
结论：尽管文献中没有临床反馈，年轻患者甲状旁腺功能减退症引起的全身性低矿化/发育不良牙齿可作为牙釉质发育不全（全身性釉质缺损）进行保守治疗，中期效果满意。
结论：这项研究为家族性孤立性甲状旁腺功能减退症引起的釉质发育不全的治疗提供了新的见解，有助于改善类似病例的患者预后。
