背景:我们在这项研究中的目的是确定在sanlüurfa省诊断的皮肤利什曼病(CL)患者的非典型临床表现。
方法:这项回顾性研究包括2019年10月至2022年8月间在CL流行地区的sanlüurfaOrientalBoil诊断和治疗中心诊断为CL的1751例患者中213例临床表现不典型的患者。
结果:我们发现非典型CL的患病率为12.1%。最常见的不典型病变为21号(9.8%),丹毒16(7.5%),脓疱性16(7.5%),累犯15(7%),湿疹15(7%),湿疹样13例(6.1%),坏疽样脓皮病12(5.6%),和孢子囊12(5.6%)。其他有不典型临床表现的病变:查耳松样,疣状,牙窦状,psoriasiform,zosteriform,淋巴瘤样,幼年黄色肉芽肿样,火山般的,牙旁,基底细胞癌样,鳞状细胞癌样,唇疱疹样,角化棘皮瘤样,chancriform,环形,苔藓样,乳腺细胞瘤样,瘢痕疙瘩,表皮样囊肿样,卡波西肉瘤样,瘢痕利什曼病,肉芽肿性唇炎样,菌丝瘤样,传染性软疣,盘状红斑狼疮样,和皮肤纤维瘤一样.
结论:除了先前报道的非典型临床表现外,我们还定义了皮肤纤维瘤样,卡波西肉瘤样,牙窦状,幼年黄色肉芽肿样,肥大细胞瘤样,和表皮样囊肿.应该记住,CL可以在临床上模仿许多传染性疾病,炎症,和肿瘤疾病,这在长期不愈合的病变的鉴别诊断中应该考虑,尤其是在流行地区。关键信息关于这个主题的已知信息:CL被称为皮肤病学中的伟大模仿者疾病。这项研究补充说:除了以前报道的非典型临床表现外,我们还定义了皮肤纤维瘤样,卡波西肉瘤样,牙窦状,幼年黄色肉芽肿样,肥大细胞瘤样,和表皮样囊肿.这项研究如何影响研究,实践,或策略:CL可以在临床上模仿许多传染性,炎症和肿瘤疾病,这在长期不愈合的病变的鉴别诊断中应该考虑,尤其是在流行地区。
BACKGROUND: Our objective in this study is to determine the atypical clinical presentations of cutaneous leishmaniasis (CL) patients diagnosed in Şanlıurfa province.
METHODS: This retrospective study included 213 patients with atypical clinical presentations among 1751 patients diagnosed with CL between October 2019 and August 2022 in Şanlıurfa Oriental Boil Diagnosis and Treatment Center located in an endemic region for CL.
RESULTS: We found the prevalence of atypical CL to be 12.1%. The most common atypical lesions were lupoid 21 (9.8%), erysipeloid 16 (7.5%), impetiginous 16 (7.5%), recidivan 15 (7%), eczematous 15 (7%), ecthyma-like 13 (6.1%), pyoderma gangrenous-like 12 (5.6%), and sporotrichoid 12 (5.6%). Other lesions with atypical clinical presentations: chalazion-like, verrucous, dental sinus-like, psoriasiform, zosteriform, lymphoma-like, juvenile xanthogranuloma-like, volcano-like, paronychial, basal cell carcinoma-like, squamous cell carcinoma-like, herpes labialis-like, keratoacanthoma-like, chancriform, annular, lichenoid, mastocitoma-like, keloidal, epidermoid cyst-like, kaposi sarcoma-like, scar leishmaniasis, granulomatous cheilitis-like, mycetoma-like, molluscum contagiosum-like, discoid lupus erythematosus-like, and dermatofibroma-like.
CONCLUSIONS: In addition to the atypical clinical presentations previously reported, we also defined dermatofibroma-like, Kaposi sarcoma-like, dental sinus-like, juvenile xanthogranuloma-like, mastocytoma-like, and epidermoid cyst-like. It should be kept in mind that CL can clinically mimic many infectious, inflammatory, and neoplastic diseases, which should be considered in the differential diagnosis of long-term non-healing lesions, especially in endemic areas. Key message What is already known on this subject: CL is known as the great imitator disease in dermatology. What this study adds: In addition to the atypical clinical presentations previously reported, we also defined dermatofibroma-like, Kaposi sarcoma-like, dental sinus-like, juvenile xanthogranuloma-like, mastocytoma-like, and epidermoid cyst-like. How this study might affect research, practice, or policy: CL can clinically mimic many infectious, inflammatory and neoplastic diseases, which should be considered in the differential diagnosis of long-term non-healing lesions, especially in endemic areas.