目标:复杂,三维骨缺损在常规种植牙科中仍然是具有挑战性的情况。这项研究的目的是使用患者特定的钛网评估定制骨再生中的植入物存活率。
方法:患者(n=21,植入物36)在5.7±0.38年后接受了患者特异性钛网的增强手术。存活率,种植体周炎的临床参数(探查出血[BOP]和化脓),和影像学检查进行了评估。使用图像评估程序计算种植体周围边缘骨丢失(MBL)。此外,各种因素对牙周炎等治疗结果的影响,吸烟,专业维修,应用口腔健康影响概况(OHIP)评估糖尿病或糖尿病以及对生活质量的影响。
结果:植入物存活率为97%,一个植入物在下颌丢失。在观察期结束时,MBL显示近端0.13±1.84mm和远端-0.13±1.73mm。与上颌相比,下颌显示出更多的MBL内侧(p=.034,聚类调整)。牙周炎与中端和远端MBL显著相关(p<0.05)。阳性BOP(四个植入物)与MBL内侧(p=.0031)和远端(p=.0018)显着相关。MBL与纵隔化脓(p<0.0001)和远端化脓(p<0.0001)显着相关。
结论:CBR®在至少5年的随访后可获得较高的植入物存活率和稳定的边缘骨增强。牙周炎似乎在BOP和化脓表明的长期稳定性中起着市长的作用。
OBJECTIVE: Complex, three-dimensional bony defects still represent challenging situations in routine implant dentistry. The aim of this study was to evaluate implant survival in customized bone regeneration using a patient-specific titanium mesh.
METHODS: Patients (n = 21, implants 36) who had obtained an augmentation procedure with patient-specific titanium mesh were examined after 5.7 ± 0.38 years. Survival rate, clinical parameters for periimplantitis (Bleeding on Probing [BOP] and suppuration), and radiographic examination were evaluated. Peri-implant marginal bone loss (MBL) was calculated by using an image assessment program. Additionally, the influence of various factors on treatment outcomes such as periodontitis, smoking, professional maintenance, or diabetes was assessed as well as the impact on quality of life applying the Oral Health Impact Profile (OHIP).
RESULTS: The implant survival rate was 97%, with one implant loss in the lower jaw. At the end of the observation period, MBL showed mesial 0.13 ± 1.84 mm and distal -0.13 ± 1.73 mm. The lower jaw showed significant more MBL mesial compared with the upper jaw (p = .034, cluster-adjusted). Periodontitis was significantly associated with MBL mesial and distal (p < .05). Positive BOP (four implants) was significantly associated with MBL mesial (p = .0031) and distal (p = .0018). MBL was significantly associated with suppuration mesial (p < .0001) and distal (p < .0001).
CONCLUSIONS: CBR® results in high implant survival rate and stabilized augmented marginal bone after follow-up of minimum 5 years. Periodontitis seems to play the mayor role for long-term stability indicated by BOP and suppuration.