PDF(Pubmed)
Abstract：
BACKGROUND: Beta-tricalcium phosphate (β-TCP) is a biocompatible ceramic material widely used in the field of oral regeneration. Due to its excellent biological and mechanical properties, it is increasingly utilized for alveolar ridge augmentation or guided bone regeneration (GBR). With recent advances in computer-aided design and manufacturing (CAD/CAM), β-TCP can now be used in the form of digitally designed patient-specific scaffolds for customized bone regeneration (CBR) of advanced defects in a two-stage implant therapy concept. In this case report following the CARE case report guidelines, we present a novel application of a patient-specific β-TCP scaffold in pre-implant mandibular alveolar ridge augmentation.
METHODS: A 63-year-old female patient with significant horizontal bone loss in the posterior mandible was treated with a custom β-TCP scaffold in the context of a two-stage backward-planned implant therapy. Cone-beam computed tomography nine months after augmentation showed successful integration of the scaffold into the surrounding bone, allowing implant placement. Follow-up until two years after initial surgery showed excellent oral and peri-implant health.
CONCLUSIONS: This case highlights the potential of patient-specific β-TCP scaffolds for alveolar ridge augmentation and their advantage over traditional techniques, including avoidance of xeno-, allo-, and autografts. The results provide encouraging evidence for their use in clinical practice. Patient-specific β-TCP scaffolds may be a promising alternative for clinicians seeking to provide their patients with safe, predictable, and effective alveolar ridge augmentation results in customized bone regeneration procedures.
METHODS: A 63-year-old female patient with significant horizontal bone loss in the posterior mandible was treated with a custom β-TCP scaffold in the context of a two-stage backward-planned implant therapy. Cone-beam computed tomography nine months after augmentation showed successful integration of the scaffold into the surrounding bone, allowing implant placement. Follow-up until two years after initial surgery showed excellent oral and peri-implant health.
CONCLUSIONS: This case highlights the potential of patient-specific β-TCP scaffolds for alveolar ridge augmentation and their advantage over traditional techniques, including avoidance of xeno-, allo-, and autografts. The results provide encouraging evidence for their use in clinical practice. Patient-specific β-TCP scaffolds may be a promising alternative for clinicians seeking to provide their patients with safe, predictable, and effective alveolar ridge augmentation results in customized bone regeneration procedures.
摘要：
背景：β-磷酸三钙（β-TCP）是一种广泛用于口腔再生领域的生物相容性陶瓷材料。由于其优异的生物和机械性能，它越来越多地用于牙槽脊增强或引导骨再生（GBR）。随着计算机辅助设计和制造(CAD/CAM)的最新进展，β-TCP现在可以以数字设计的患者特定支架的形式使用，用于两阶段植入治疗概念中的高级缺陷的定制骨再生（CBR）。在遵循CARE病例报告指南的病例报告中，我们提出了一种患者特异性β-TCP支架在植入前下颌牙槽脊增强中的新应用。
方法：一名63岁女性患者在后下颌骨有明显的水平骨丢失，在两阶段后计划植入治疗的背景下，采用定制的β-TCP支架进行治疗。增强后9个月，锥形束计算机断层扫描显示支架成功整合到周围的骨骼中，允许植入物放置。最初手术后两年的随访显示口腔和种植体周围的健康状况良好。
结论：该案例突出了患者特异性β-TCP支架用于牙槽脊增强的潜力及其相对于传统技术的优势，包括避免异种，allow-,和自体移植物。结果为其在临床实践中的使用提供了令人鼓舞的证据。患者特异性β-TCP支架可能是临床医生寻求为患者提供安全，可预测的,和有效的牙槽脊增强导致定制的骨再生程序。
方法：一名63岁女性患者在后下颌骨有明显的水平骨丢失，在两阶段后计划植入治疗的背景下，采用定制的β-TCP支架进行治疗。增强后9个月，锥形束计算机断层扫描显示支架成功整合到周围的骨骼中，允许植入物放置。最初手术后两年的随访显示口腔和种植体周围的健康状况良好。
结论：该案例突出了患者特异性β-TCP支架用于牙槽脊增强的潜力及其相对于传统技术的优势，包括避免异种，allow-,和自体移植物。结果为其在临床实践中的使用提供了令人鼓舞的证据。患者特异性β-TCP支架可能是临床医生寻求为患者提供安全，可预测的,和有效的牙槽脊增强导致定制的骨再生程序。
