Electrocardiography (ECG) has emerged as a ubiquitous diagnostic tool for the identification and characterization of diverse cardiovascular pathologies. Wearable health monitoring devices, equipped with on-device biomedical artificial intelligence (AI) processors, have revolutionized the acquisition, analysis, and interpretation of ECG data. However, these systems necessitate AI processors that exhibit flexible configuration, facilitate portability, and demonstrate optimal performance in terms of power consumption and latency for the realization of various functionalities. To address these challenges, this study proposes an instruction-driven convolutional neural network (CNN) processor. This processor incorporates three key features: (1) An instruction-driven CNN processor to support versatile ECG-based application. (2) A Processing element (PE) array design that simultaneously considers parallelism and data reuse. (3) An activation unit based on the CORDIC algorithm, supporting both Tanh and Sigmoid computations. The design has been implemented using 110 nm CMOS process technology, occupying a die area of 1.35 mm2 with 12.94 µW power consumption. It has been demonstrated with two typical ECG AI applications, including two-class (i.e., normal/abnormal) classification and five-class classification. The proposed 1-D CNN algorithm performs with a 97.95% accuracy for the two-class classification and 97.9% for the five-class classification, respectively.

Background: Chest radiography is the standard method for detecting rib fractures. Our study aims to develop an artificial intelligence (AI) model that, with only a relatively small amount of training data, can identify rib fractures on chest radiographs and accurately mark their precise locations, thereby achieving a diagnostic accuracy comparable to that of medical professionals. Methods: For this retrospective study, we developed an AI model using 540 chest radiographs (270 normal and 270 with rib fractures) labeled for use with Detectron2 which incorporates a faster region-based convolutional neural network (R-CNN) enhanced with a feature pyramid network (FPN). The model\'s ability to classify radiographs and detect rib fractures was assessed. Furthermore, we compared the model\'s performance to that of 12 physicians, including six board-certified anesthesiologists and six residents, through an observer performance test. Results: Regarding the radiographic classification performance of the AI model, the sensitivity, specificity, and area under the receiver operating characteristic curve (AUROC) were 0.87, 0.83, and 0.89, respectively. In terms of rib fracture detection performance, the sensitivity, false-positive rate, and free-response receiver operating characteristic (JAFROC) figure of merit (FOM) were 0.62, 0.3, and 0.76, respectively. The AI model showed no statistically significant difference in the observer performance test compared to 11 of 12 and 10 of 12 physicians, respectively. Conclusions: We developed an AI model trained on a limited dataset that demonstrated a rib fracture classification and detection performance comparable to that of an experienced physician.

Brain-computer interfaces (BCIs), representing a transformative form of human-computer interaction, empower users to interact directly with external environments through brain signals. In response to the demands for high accuracy, robustness, and end-to-end capabilities within BCIs based on motor imagery (MI), this paper introduces STaRNet, a novel model that integrates multi-scale spatio-temporal convolutional neural networks (CNNs) with Riemannian geometry. Initially, STaRNet integrates a multi-scale spatio-temporal feature extraction module that captures both global and local features, facilitating the construction of Riemannian manifolds from these comprehensive spatio-temporal features. Subsequently, a matrix logarithm operation transforms the manifold-based features into the tangent space, followed by a dense layer for classification. Without preprocessing, STaRNet surpasses state-of-the-art (SOTA) models by achieving an average decoding accuracy of 83.29% and a kappa value of 0.777 on the BCI Competition IV 2a dataset, and 95.45% accuracy with a kappa value of 0.939 on the High Gamma Dataset. Additionally, a comparative analysis between STaRNet and several SOTA models, focusing on the most challenging subjects from both datasets, highlights exceptional robustness of STaRNet. Finally, the visualizations of learned frequency bands demonstrate that temporal convolutions have learned MI-related frequency bands, and the t-SNE analyses of features across multiple layers of STaRNet exhibit strong feature extraction capabilities. We believe that the accurate, robust, and end-to-end capabilities of the STaRNet will facilitate the advancement of BCIs.

This paper proposes a convolutional neural network (CNN) model of the signal distribution control algorithm (SDCA) to maximize the dynamic vehicular traffic signal flow for each junction phase. The aim of the proposed algorithm is to determine the reward value and new state. It deconstructs the routing components of the current multi-directional queuing system (MDQS) architecture to identify optimal policies for every traffic scenario. Initially, the state value is divided into a function value and a parameter value. Combining these two scenarios updates the resulting optimized state value. Ultimately, an analogous criterion is developed for the current dataset. Next, the error or loss value for the present scenario is computed. Furthermore, utilizing the Deep Q-learning methodology with a quad agent enhances previous study discoveries. The recommended method outperforms all other traditional approaches in effectively optimizing traffic signal timing.

This work addresses the challenge of classifying multiclass visual EEG signals into 40 classes for brain-computer interface applications using deep learning architectures. The visual multiclass classification approach offers BCI applications a significant advantage since it allows the supervision of more than one BCI interaction, considering that each class label supervises a BCI task. However, because of the nonlinearity and nonstationarity of EEG signals, using multiclass classification based on EEG features remains a significant challenge for BCI systems. In the present work, mutual information-based discriminant channel selection and minimum-norm estimate algorithms were implemented to select discriminant channels and enhance the EEG data. Hence, deep EEGNet and convolutional recurrent neural networks were separately implemented to classify the EEG data for image visualization into 40 labels. Using the k-fold cross-validation approach, average classification accuracies of 94.8% and 89.8% were obtained by implementing the aforementioned network architectures. The satisfactory results obtained with this method offer a new implementation opportunity for multitask embedded BCI applications utilizing a reduced number of both channels (<50%) and network parameters (<110 K).

The application of wearable electroencephalogram (EEG) devices is growing in brain-computer interfaces (BCI) owing to their good wearability and portability. Compared with conventional devices, wearable devices typically support fewer EEG channels. Devices with few-channel EEGs have been proven to be available for steady-state visual evoked potential (SSVEP)-based BCI. However, fewer-channel EEGs can cause the BCI performance to decrease. To address this issue, an attention-based complex spectrum-convolutional neural network (atten-CCNN) is proposed in this study, which combines a CNN with a squeeze-and-excitation block and uses the spectrum of the EEG signal as the input. The proposed model was assessed on a wearable 40-class dataset and a public 12-class dataset under subject-independent and subject-dependent conditions. The results show that whether using a three-channel EEG or single-channel EEG for SSVEP identification, atten-CCNN outperformed the baseline models, indicating that the new model can effectively enhance the performance of SSVEP-BCI with few-channel EEGs. Therefore, this SSVEP identification algorithm based on a few-channel EEG is particularly suitable for use with wearable EEG devices.

Recent advancements in 3D modeling have revolutionized various fields, including virtual reality, computer-aided diagnosis, and architectural design, emphasizing the importance of accurate quality assessment for 3D point clouds. As these models undergo operations such as simplification and compression, introducing distortions can significantly impact their visual quality. There is a growing need for reliable and efficient objective quality evaluation methods to address this challenge. In this context, this paper introduces a novel methodology to assess the quality of 3D point clouds using a deep learning-based no-reference (NR) method. First, it extracts geometric and perceptual attributes from distorted point clouds and represent them as a set of 1D vectors. Then, transfer learning is applied to obtain high-level features using a 1D convolutional neural network (1D CNN) adapted from 2D CNN models through weight conversion from ImageNet. Finally, quality scores are predicted through regression utilizing fully connected layers. The effectiveness of the proposed approach is evaluated across diverse datasets, including the Colored Point Cloud Quality Assessment Database (SJTU_PCQA), the Waterloo Point Cloud Assessment Database (WPC), and the Colored Point Cloud Quality Assessment Database featured at ICIP2020. The outcomes reveal superior performance compared to several competing methodologies, as evidenced by enhanced correlation with average opinion scores.

The need for non-interactive human recognition systems to ensure safe isolation between users and biometric equipment has been exposed by the COVID-19 pandemic. This study introduces a novel Multi-Scaled Deep Convolutional Structure for Punctilious Human Gait Authentication (MSDCS-PHGA). The proposed MSDCS-PHGA involves segmenting, preprocessing, and resizing silhouette images into three scales. Gait features are extracted from these multi-scale images using custom convolutional layers and fused to form an integrated feature set. This multi-scaled deep convolutional approach demonstrates its efficacy in gait recognition by significantly enhancing accuracy. The proposed convolutional neural network (CNN) architecture is assessed using three benchmark datasets: CASIA, OU-ISIR, and OU-MVLP. Moreover, the proposed model is evaluated against other pre-trained models using key performance metrics such as precision, accuracy, sensitivity, specificity, and training time. The results indicate that the proposed deep CNN model outperforms existing models focused on human gait. Notably, it achieves an accuracy of approximately 99.9% for both the CASIA and OU-ISIR datasets and 99.8% for the OU-MVLP dataset while maintaining a minimal training time of around 3 min.

[This corrects the article DOI: 10.3389/fonc.2022.951973.].

Nucleic acid-binding proteins (NABPs), including DNA-binding proteins (DBPs) and RNA-binding proteins (RBPs), play important roles in essential biological processes. To facilitate functional annotation and accurate prediction of different types of NABPs, many machine learning-based computational approaches have been developed. However, the datasets used for training and testing as well as the prediction scopes in these studies have limited their applications. In this paper, we developed new strategies to overcome these limitations by generating more accurate and robust datasets and developing deep learning-based methods including both hierarchical and multi-class approaches to predict the types of NABPs for any given protein. The deep learning models employ two layers of convolutional neural network and one layer of long short-term memory. Our approaches outperform existing DBP and RBP predictors with a balanced prediction between DBPs and RBPs, and are more practically useful in identifying novel NABPs. The multi-class approach greatly improves the prediction accuracy of DBPs and RBPs, especially for the DBPs with ~12% improvement. Moreover, we explored the prediction accuracy of single-stranded DNA binding proteins and their effect on the overall prediction accuracy of NABP predictions.