Fossil fuel companies hold enormous political, economic, and knowledge production power. Recently, industry operators have pivoted from pushing climate denialism to campaigns aimed at individualizing responsibility for climate crisis. In this paper, we focus on one related outcome of such efforts - people\'s experiences of complicity - here in the context of unconventional oil and gas (UOG) production. We ask: How do mobilized activists experience fossil fuel scapegoating, and what does it mean for their goals as they organize against UOG production? We show that even activists fighting UOG production feel complicit in fossil fuel production, and these feelings of complicity diminish their demands for UOG accountability. We argue that these outcomes have been especially pernicious in cultural contexts like that of the United States, where neoliberal ideologies are normalized, centering personal responsibility, individualization, and identification as consumers rather than citizens. We marshal an extensive qualitative dataset and advance a theory of complicity as a way to understand: a) how social movements intersect with neoliberalized patterns of life; b) how experiences of complicity affect activism; and c) how this may contribute to fossil fuel firms\' goals of undercutting organizing. We end by examining how a sub-set of activists works to dismantle this complicity narrative.

Imprisonment may sometimes be a justified form of punishment. Yet the U.S. carceral system suffers from appalling problems of justice-in who is put into prisons, in how imprisoned people are treated, and in downstream personal and community health impacts. Medical personnel working in prisons and jails take on risky work for highly vulnerable and underserved patients. They are to be lauded for their professional commitments. Yet at the same time, prison care undercuts the ability of medical personnel to uphold their own professional standards and sometimes fails in even basic health protection. Doctors in prisons are stuck between their commitment to vulnerable patients and complicity in a system that requires their participation to uphold its constitutionality. Medical ethics is frayed in prisons, and the problem deserves our attention.

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Chater & Loewenstein offer an incisive criticism of how behavioral sciences and public policy have become complicit with corporations in blaming public health and societal problems on individual weaknesses, thus deflecting support away from systemic reforms. However, their analysis stops short of holding the field to account in one important respect: its preoccupation with human irrationality and weakness.

Background: In the twenty-first century, literatures from Central and Eastern Europe are marked by a boom of documentary fiction portraying complicity Nazi perpetration, Soviet terror, or other instances of 20th century mass violence and totalitarianism. Since understanding the past serves requirements of the present, the boom prompts the question: Why the interest in past complicities now? My hypothesis is that the texts address convergences between involvements in past acts of mass violence and current forms of participation in wrongdoings in neoliberalism. While these issues differ profoundly, they are related: structurally, both present the challenge of forming a nuanced notion of participation. Historically, they are related since justifications of past involvements have established the terminology, narratives, and heuristics in which terror, repression, and mass violence are subsequently discussed, thus forming the frame for negotiating current problematic involvements. Method: Critical discourse analysis is used to scrutinize the legal concept of complicity and combined it with close readings of passages from four literary texts to outline how attention to reciprocity in language can enhance our understanding of problematic involvement. Results: Literary portrayals of historical complicity are ambivalent; they can help to find models for comprehending issues of the present in cultural memory, but they can also serve to establish distance between present and past to appease the sense that all is not quite well, even after the demise of Nazi and Soviet terror. The article outlines two modes of distancing: a) spacio-temporal distancing of the commemorating point of view in \'the West\' from the portrayed violence in \'the East\', and b) moral distancing that casts the audience as superior to complicit characters. Conclusion: By pressing for analytic or consoling distance, both strategies of distancing amount to a complicity with the transmission of discourses that justify, excuse, or deny mass violence and totalitarian terror.

Understanding the mechanisms of the relationship between the nervous and immune systems within the framework of the concept of the key role of inflammation, taking into account the involved genetic factors in the development of a wide range of combined forms of somatic and mental diseases, is of interest for research as well as for the development of new approaches to early diagnosis and more effective treatment of these diseases. This review analyzes the immune mechanisms of the development of mental disorders in patients with somatic diseases, in particular, the transmission of an inflammatory signal from the periphery to the CNS and the implementation of the influence of inflammatory factors on neurochemical systems that determine the characteristics of mental functioning. Particular attention is paid to the processes underlying the disruption of the blood-brain barrier caused by peripheral inflammation. Modulation of neurotransmission, changes in neuroplasticity, changes in regional activity of the brain in areas associated with the functions of threat recognition, cognitive processes and memory function, the effect of cytokines on the hypothalamic-pituitary-adrenal system are considered as mechanisms of action of inflammatory factors in the brain. The need to take into account variations in the genes of pro-inflammatory cytokines, which may be the cause of increased genetic vulnerability associated with the risk mental disorders in patients suffering from a certain somatic disease, is emphasized.
Понимание механизмов связи нервной и иммунной систем в рамках концепции ключевой роли воспаления с учетом вовлеченных генетических факторов в развитии широкого круга сочетанных форм соматических и психических заболеваний вызывает интерес как для фундаментальной науки, так и для разработки новых подходов к ранней диагностике и более эффективной терапии этих форм. В настоящем обзоре проведен анализ иммунных механизмов психических расстройств на фоне соматической патологии, в частности передачи воспалительного сигнала с периферии в центральную нервную систему и реализации влияния воспалительных факторов на нейрохимические системы, определяющие особенности психического функционирования. Особое внимание уделено процессам, лежащим в основе нарушения гематоэнцефалического барьера, вызванного периферическим воспалением. В качестве механизмов действия воспалительных факторов в головном мозге рассмотрены модуляция нейротрансмиссии, изменения нейропластичности, изменение региональной активности головного мозга в зонах, связанных с функциями распознавания угрозы, когнитивными процессами и функцией памяти, влияние цитокинов на гипоталамо-гипофизарно-надпочечниковую систему. Подчеркивается необходимость учета вариаций в генах провоспалительных цитокинов, что может быть причиной повышенной генетической уязвимости, связанной с риском развития психических расстройств у пациентов, страдающих определенным соматическим заболеванием.

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In this collection we develop the concept of \"complicity\" as a means to understand how medical sociologists might be allied in unexpected or uncomfortable ways with dominant structures of power. After giving examples of complicity from our own research, we introduce existing scholarship on complicity, describing it as a concept that comes coupled with a sense of responsibility and that is related to, yet distinct from, a range of other terms including reflexivity, collusion, guilt, and shame. We also discuss how complicity has been described to occur at the level of the institution, within theoretical frameworks, and during mundane moments that we face on a day-to-day basis. Building on this review, we hypothesise that medical sociology - where access to fieldsites is often hard won, where \"researching up\" in medical and scientific institutions is common, and where our own work frequently concerns matters central to medical institutions themselves - is a discipline wherein mundane complicity is likely. Following this gathering exercise, we introduce the interventions that comprise this collection: interventions from a diversity of sociologists of health and illness who, perhaps for the first time in written form, account for how complicities of various kinds came to shape their work and how, with varying levels of success, they have sought redress. We close by offering some insight into the process of developing this collection, celebrating its successes while also acknowledging that many gaps and complicities remain.

Pancreatic ductal adenocarcinomas are distinguished by their robust desmoplasia, or fibroinflammatory response. Dominated by non-malignant cells, the mutated epithelium must therefore combat, cooperate with or co-opt the surrounding cells and signalling processes in its microenvironment. It is proposed that an invasive pancreatic ductal adenocarcinoma represents the coordinated evolution of malignant and non-malignant cells and mechanisms that subvert and repurpose normal tissue composition, architecture and physiology to foster tumorigenesis. The complex kinetics and stepwise development of pancreatic cancer suggests that it is governed by a discrete set of organizing rules and principles, and repeated attempts to target specific components within the microenvironment reveal self-regulating mechanisms of resistance. The histopathological and genetic progression models of the transforming ductal epithelium must therefore be considered together with a programme of stromal progression to create a comprehensive picture of pancreatic cancer evolution. Understanding the underlying organizational logic of the tumour to anticipate and pre-empt the almost inevitable compensatory mechanisms will be essential to eradicate the disease.