目的:本研究旨在评估亚的斯亚贝巴严重急性营养不良的5岁以下儿童的生存状况和死亡率预测因素。埃塞俄比亚。
方法:对亚的斯亚贝巴稳定中心收治的5岁以下儿童随机选择的422份病历进行了回顾性队列研究,埃塞俄比亚。进行生存分析和Cox回归分析以确定结果之前花费的时间和预期结果的预测因素。
方法:亚的斯亚贝巴四家政府医院的稳定中心,埃塞俄比亚:TikurAnbessa专科医院,Zewditu纪念医院,Yekatit12医院和Tirunesh北京医院参与者:亚的斯亚贝巴四家政府医院收治的435名5岁以下严重营养不良儿童中,埃塞俄比亚,从2020年1月到2022年12月,我们能够跟踪422条完整记录。由于这些儿童的病史信息缺失,其余13份医疗记录被发现不完整。
方法:主要结果是严重急性营养不良的5岁以下儿童进入稳定中心后的生存状况。次要结果是这些儿童的生存预测因子。
结果:在422名儿童中,44人(10.4%)死亡,发病率为10.3/1000人日。中位住院时间为8天。完全接种(调整后的HR(AHR)0.2,95%CI0.088至0.583,p<0.05),喂养方式(F-75)(AHR0.2,95%CI0.062至0.651,p<0.01),静脉输液(AHR3.7,95%CI1.525至8.743,p<0.01),HIV的存在(AHR2.2,95%CI1.001至4.650,p<0.05),肺炎(AHR2.2,95%CI1.001~4.650,p<0.01)和休克发生率(AHR3.5,95%CI1.451~8.321,p<0.01)被确定为死亡率的显著预测因子.
结论:该研究发现生存率略高于社会和公共卫生经济学研究组设定的可接受范围。疫苗接种状况等因素,艾滋病毒,肺炎,震惊,静脉输液和不进食F-75预测死亡率。
OBJECTIVE: This study aims to assess the survival status and predictors of mortality among under-5 children with severe acute malnutrition in Addis Ababa, Ethiopia.
METHODS: A retrospective cohort study was employed on randomly selected 422 medical records of children under the age of 5 admitted to stabilisation centres in Addis Ababa, Ethiopia. Survival analysis and Cox regression analysis were conducted to determine time spent before the outcome and predictors of desired outcome.
METHODS: The stabilisation centres in four governmental hospitals in Addis Ababa, Ethiopia: Tikur Anbessa Specialised Hospital, Zewditu Memorial Hospital, Yekatit 12 Hospital and Tirunesh Beijing Hospital PARTICIPANTS: Of 435 severely malnourished children under the age of 5 admitted to four governmental hospitals in Addis Ababa, Ethiopia, from January 2020 to December 2022, we were able to trace 422 complete records. The remaining 13 medical records were found to be incomplete due to missing medical history information for those children.
METHODS: The primary outcome is the survival status of under-5 children with severe acute malnutrition after admission to the stabilisation centres. The secondary outcome is predictors of survival among these children.
RESULTS: Of 422 children, 44 (10.4%) died, with an incidence rate of 10.3 per 1000 person-days. The median hospital stay was 8 days. Full vaccination (adjusted HR (AHR) 0.2, 95% CI 0.088 to 0.583, p<0.05), feeding practices (F-75) (AHR 0.2, 95% CI 0.062 to 0.651, p<0.01), intravenous fluid administration (AHR 3.7, 95% CI 1.525 to 8.743, p<0.01), presence of HIV (AHR 2.2, 95% CI 1.001 to 4.650, p<0.05), pneumonia (AHR 2.2, 95% CI 1.001 to 4.650, p<0.01) and occurrence of shock (AHR3.5, 95% CI 1.451 to 8.321, p<0.01) were identified as significant predictors of mortality.
CONCLUSIONS: The study identified a survival rate slightly higher than the acceptable range set by the social and public health economics study group. Factors like vaccination status, HIV, pneumonia, shock, intravenous fluid and the absence of feeding F-75 predicted mortality.