背景:唇裂伴或不伴腭裂(CL/P)是最常见的先天性面部畸形,源于多因素原因。
目的:我们的研究旨在确定腭裂的患病率和特征,确定相关的危险因素,为早期干预提供预防和产前检测信息,并评估腭裂术后康复方案。
方法:本研究采用回顾性描述和临床方法。
方法:这项研究包括103名儿童和青少年头颈外科诊所治疗的腭裂患儿,临床儿科,Warmia和Mazury大学。
方法:我们对记录进行了全面评估,考虑到诸如性别之类的变量,裂隙类型,产妇职业,父母教育,和裂缝的家族史。使用R软件版本GPL-3和有序逻辑回归分析进行数据分析。
结果:值得注意的是,在怀孕期间经历了显著压力的母亲所生的孩子出现双侧腭裂的几率增加了9.4倍.相反,没有发现实质性证据支持孩子性别的影响,出生顺序,体重,产妇接触工作场所毒素,感染,或因变量的药物毒性。
结论:我们的研究结果表明,父母有唇裂病史的儿童和母亲受教育程度较低的儿童更容易发生双侧腭裂。此外,母亲在怀孕期间经历压力所生的孩子面临双侧腭裂的风险增加.重要的是要注意,关于儿童各种left裂手术技术后康复的文献很少。
BACKGROUND: Cleft lip with or without
cleft palate (CL/P) stands as the most common congenital facial anomaly, stemming from multifactorial causes.
OBJECTIVE: Our study aimed to ascertain the prevalence and characteristics of
cleft palates, identify associated risk factors to inform prevention and prenatal detection for early intervention, and assess postoperative rehabilitation protocols for
cleft palates.
METHODS: This study employs a retrospective descriptive and clinical approach.
METHODS: The study includes 103 children with
cleft palates treated at the Department of Head and Neck Surgery Clinic for Children and Young Adults, Department of Clinical Pediatrics, University of Warmia and Mazury.
METHODS: We conducted a thorough evaluation of records, considering variables such as sex,
cleft type, maternal occupation, parental education, and family history of clefts. Data analysis was carried out using R software version GPL-3 and ordinal logistic regression analyses.
RESULTS: Notably, children born to mothers who experienced significant stress during pregnancy exhibited a 9.4-fold increase in the odds of having bilateral cleft palates. Conversely, no substantial evidence was found to support the influence of the child\'s sex, birth order, body mass, maternal exposure to workplace toxins, infections, or drug toxicity on the dependent variable.
CONCLUSIONS: Our findings suggest that children with parents who have a history of clefts and those with less educated mothers are more likely to develop bilateral cleft palates. Additionally, children born to mothers experiencing stress during pregnancy face an increased risk of bilateral cleft palates. It is important to note that there is a paucity of literature on rehabilitation following various cleft palate surgical techniques in children.