Abstract：
The objective of this study is to utilize the Nasometer to objectively assess velopharyngeal competence, specifically through the quantification of nasalance. Initial calibration of the nasometer was conducted on American adults. The objective of this study was to validate the use of the nasometer for the objective diagnosis of velopharyngeal insufficiency (VPI) in French children born with a total cleft lip and palate and to select relevant verbal stimuli for clinical practice.
METHODS: The nasalance scores of 42 children aged 8 to 10 years old, born with a cleft lip and palate, were collected and compared with 50 control children. The scores were then analyzed in relation to 31 verbal stimuli from the French corpus created for this study (sentences and syllables). The most relevant threshold values were determined by receiver operating characteristic curves, which exhibited the highest sensitivity and specificity.
RESULTS: The results demonstrated statistically significant differences (p < 0.05) in the mean nasalance scores of the control and cleft groups for all verbal stimuli containing oral phonemes. Threshold values with good diagnostic accuracy were defined, and 15 verbal stimuli were selected for use in clinical practice.
CONCLUSIONS: The nasalance threshold values defined in this study can be utilized for the objective diagnosis of velopharyngeal insufficiency (VPI) and the subsequent monitoring of French children aged 8 to 10 years old, born with a cleft lip and palate.
METHODS: The nasalance scores of 42 children aged 8 to 10 years old, born with a cleft lip and palate, were collected and compared with 50 control children. The scores were then analyzed in relation to 31 verbal stimuli from the French corpus created for this study (sentences and syllables). The most relevant threshold values were determined by receiver operating characteristic curves, which exhibited the highest sensitivity and specificity.
RESULTS: The results demonstrated statistically significant differences (p < 0.05) in the mean nasalance scores of the control and cleft groups for all verbal stimuli containing oral phonemes. Threshold values with good diagnostic accuracy were defined, and 15 verbal stimuli were selected for use in clinical practice.
CONCLUSIONS: The nasalance threshold values defined in this study can be utilized for the objective diagnosis of velopharyngeal insufficiency (VPI) and the subsequent monitoring of French children aged 8 to 10 years old, born with a cleft lip and palate.
摘要：
这项研究的目的是利用鼻塞来客观评估咽喉功能，特别是通过对nasalance的量化。对美国成年人进行了鼻压计的初始校准。这项研究的目的是验证使用鼻压计客观诊断唇腭裂的法国儿童的咽喉功能不全（VPI），并选择相关的言语刺激进行临床实践。
方法：42名8至10岁儿童的鼻音评分，天生唇腭裂，收集并与50名对照儿童进行比较。然后对来自本研究创建的法语语料库（句子和音节）的31种言语刺激进行了评分分析。最相关的阈值由接收器工作特性曲线确定，表现出最高的敏感性和特异性。
结果：结果显示，对于所有包含口头音素的言语刺激，对照组和裂隙组的平均鼻音评分存在统计学上的显着差异（p<0.05）。定义了具有良好诊断准确性的阈值，选择15种言语刺激用于临床实践。
结论：本研究中定义的鼻部阈值可用于客观诊断咽喉功能不全（VPI）以及随后对8至10岁的法国儿童的监测，天生唇腭裂。
方法：42名8至10岁儿童的鼻音评分，天生唇腭裂，收集并与50名对照儿童进行比较。然后对来自本研究创建的法语语料库（句子和音节）的31种言语刺激进行了评分分析。最相关的阈值由接收器工作特性曲线确定，表现出最高的敏感性和特异性。
结果：结果显示，对于所有包含口头音素的言语刺激，对照组和裂隙组的平均鼻音评分存在统计学上的显着差异（p<0.05）。定义了具有良好诊断准确性的阈值，选择15种言语刺激用于临床实践。
结论：本研究中定义的鼻部阈值可用于客观诊断咽喉功能不全（VPI）以及随后对8至10岁的法国儿童的监测，天生唇腭裂。
