目的:彩色多普勒超声(CDU)对颈动脉体瘤(CBT)的围手术期评估和随访结果的价值尚不清楚。本研究旨在探讨CDU在本中心CBT中的作用。
方法:从2015年1月至2020年12月,75例CBT患者被纳入研究。收集并分析患者的CT血管造影(CTA)和CDU数据。总结术后恢复情况及随访结果。
结果:共纳入75例患者中的91例CBTs。73.3%的患者有单侧病变,而26.7%有双侧病变。病变被归类为ShamblinI(4.4%),ShamblinII(52.7%),和ShamblinIII(42.9%)。79.5%的病灶采用手术切除治疗,12.3%采用人工血管重建颈内动脉手术切除,8.2%采用自体大隐静脉重建颈内动脉手术切除治疗。与CTA相比,CDU检测CBT的灵敏度为96.7%,CDU检测ShamblinⅠ病变的敏感性和特异性均为100%,对ShamblinⅡ的敏感性和特异性分别为100%和72.1%,分别,而ShamblinⅢ的敏感性和特异性分别为69.2%和100%,分别。CTA和CDU检测最大直径无统计学差异,CBT的体积和肿瘤末端与乳突之间的距离。79.7%的患者获得CDU随访。1例患者发生CBT复发。CDU显示1例和6例患者发生人工血管狭窄和闭塞,分别。2例自体大隐静脉闭塞。
结论:CDU能准确诊断ShamblinⅠ型CBT,对ShamblinⅡ有较高的敏感性,对ShamblinⅢCBT有较高的特异性。它在诊断中起着重要的作用,CBT的围手术期评价及随访分析。
OBJECTIVE: The value of Color Doppler Ultrasound (CDU) for perioperative evaluation and follow-up outcomes of carotid body tumor (CBT) remains elusive. This study aimed to investigate the role of CDU in CBT in our center.
METHODS: From January 2015 to December 2020, 75 patients with CBT were included in the study. Computed Tomography Angiography (CTA) and CDU data of patients were collected and analyzed. The postoperative recovery and follow-up outcomes were summarized.
RESULTS: A total of 91 CBTs in 75 patients were included in the study. 73.3% of patients had unilateral lesions, while 26.7% had bilateral lesions. Lesions were categorized as Shamblin I (4.4%), Shamblin II (52.7%), and Shamblin III (42.9%). 79.5% lesions were treated by surgical resection, 12.3% were treated by surgical resection with internal carotid artery reconstructed by artificial vessel, while 8.2% were treated by surgical resection with internal carotid artery reconstructed by autogenous great saphenous vein. Compared with CTA, the sensitivity of CDU for detection of CBT was 96.7%, the sensitivity and specificity of CDU for detection of Shamblin Ⅰ lesions were both 100%, the sensitivity and specificity for Shamblin Ⅱ were 100% and 72.1%, respectively, while the sensitivity and specificity for Shamblin Ⅲ were 69.2% and 100%, respectively. There were no statistically significant differences between CTA and CDU for detection of the maximal diameter, volume of CBT and distance between the end of the tumor and the mastoid process. 79.7% of patients were followed up with CDU. Recurrence of CBT occurred in 1 patient. CDU showed that stenosis and occlusion of artificial vessel occurred in 1 and 6 patients, respectively. Occlusion of autogenous great saphenous vein was found in 2 cases.
CONCLUSIONS: CDU can accurately diagnose Shamblin Ⅰ CBT, have high sensitivity for Shamblin Ⅱ and high specificity for Shamblin Ⅲ CBT. It plays an important role in diagnosis, perioperative evaluation and follow-up analysis of CBT.