开管(OT)毛细管柱已越来越多地用于各种分离科学领域,如CEC,LC,和SPE。特别是它们在CEC中的应用,因其出色的分离性能而备受关注。已采用各种形式的OT固定相材料,例如原位制备的聚合物,分子印迹聚合物(MIP),刷配体,宿主配体,嵌段共聚物,适体,碳纳米管,多糖,蛋白质,触手,纳米粒子,巨石,和聚电解质多层。它们以化学结合形式或物理吸附形式制备。溶胶-凝胶技术和纳米颗粒有时涉及它们的制备。也有一些独特的杂项研究,例如,采用优先吸附的流动相组分作为固定相。在这次审查中,自2007年以来的最新进展将进行详细的批判性讨论,并对日期之前的工作进行一些总结描述。
Open tubular (OT) capillary columns have been increasingly used in a variety of fields of separation science such as CEC, LC, and SPE. Especially their application in CEC has attracted a lot of attention for their outstanding separation performance. Various forms of OT stationary phase materials have been employed such as in-situ prepared polymers, molecular imprinted polymers (MIPs), brush ligands, host ligands, block copolymers, aptamers, carbon nanotubes, polysaccharides, proteins, tentacles, nanoparticles, monoliths, and polyelectrolyte multi-layers. They have been prepared either in the chemically bound format or physically adsorbed format. Sol-gel technologies and nanoparticles have been sometimes involved in their preparation. There have been also some unique miscellaneous studies, for example, adopting preferentially adsorbed mobile phase components as stationary phases. In this review, recent progresses since mostly 2007 will be critically discussed in detail with some summarized descriptions for the work before the date.