■严重创伤性脑损伤(TBI)是全球范围内的重要健康问题,与有害副作用有关。这项荟萃分析调查了严重脑外伤病例的认知和功能结果。它评估了对记忆的影响,言语和视觉能力,注意,学习,和抑郁症的存在。该研究全面概述了严重脑损伤对认知和功能领域的影响。
■当前综合荟萃分析研究的主要目的是评估和分析严重TBI对功能和认知结果的影响,包括口头,视觉,注意,学习,记忆,和情绪稳定。
■我们从三个在线数据库收集数据,包括PubMed,科克伦图书馆,和Embase。包括与严重TBI与认知和功能结局相关的病例对照试验。言语力量,视觉功能,学习能力,注意,记忆,抑郁症被认为是主要结局.
■在这项荟萃分析中,我们纳入了13项病例对照研究,共有1,442名受试者。这提供了足够的数据来确定目标结局的汇集效应大小。重度TBI对抑郁和记忆障碍诱因的影响,口头,视觉,注意,和学习能力与对照组相比,结果具有统计学意义(p<0.05)。
■严重TBI与认知和功能能力受损密切相关,包括视觉和言语障碍,记忆受损,抑郁诱因,注意力缺陷,和学习障碍。
UNASSIGNED: Severe traumatic brain injuries (TBIs) are an important health issue worldwide, which are associated with harmful side effects. This meta-analysis investigates the cognitive and functional outcomes in severe brain trauma cases. It assesses the impact on memory, verbal and visual abilities, attention, learning, and the presence of depression. The study provides a comprehensive overview of the consequences of severe brain trauma injury on cognitive and functional domains.
UNASSIGNED: The main objective of the current comprehensive meta-analysis study is to assess and analyze the impact of severe TBI on functional and cognitive outcomes, including verbal, visual, attention, learning, memory, and emotional stability.
UNASSIGNED: We collected data from three online databases, including PubMed, Cochrane Library, and Embase. Case-control trials related to severe TBI association with cognitive and functional outcomes were included. Verbal strength, visual functions, learning abilities, attention, memory, and depression were considered primary outcomes.
UNASSIGNED: We have included 13 case-control studies with 1,442 subjects in this meta-analysis, which provide adequate data to determine the pooled effect size for targeted outcomes. The effect of severe TBI on the inducement of depression and impairment of memory, verbal, visual, attention, and learning abilities compared to the control group showed statistically significant outcomes (p < 0.05).
UNASSIGNED: Severe TBI is strongly associated with impaired cognitive and functional abilities, including visual and verbal disabilities, impaired memory, depression inducement, attention deficits, and learning disabilities.