Abstract:
Elevated lactate levels are associated with a poor prognosis in patients with sepsis and shock. Intravenous glycerol administration is often used in Japan to treat patients with acute stroke or brain trauma, but such treatment can cause elevated lactate levels. We experienced a case of transient hyperlactatemia induced by intravenous glycerol administration in a patient with brain trauma. A 74-year-old woman underwent decompressive craniotomy because of loss of consciousness and brain edema. Glycerol was administered after the operation for management of the brain edema. Although the patient\'s hemodynamics remained stable, her lactate level decreased and increased repeatedly. We recognized that the elevation in her lactate level was associated with the administration of intravenous glycerol. This case suggests that intravenous glycerol administration can induce transient hyperlactatemia.
摘要:
乳酸水平升高与脓毒症和休克患者的不良预后相关。在日本,静脉注射甘油通常用于治疗急性中风或脑外伤患者,但是这种治疗会导致乳酸水平升高。我们经历了一例脑外伤患者因静脉注射甘油而引起的短暂性高乳酸血症。一名74岁的妇女因意识丧失和脑水肿而接受了开颅减压术。手术后给予甘油以治疗脑水肿。虽然患者的血流动力学保持稳定,她的乳酸水平下降和反复增加。我们认识到,她的乳酸水平升高与静脉注射甘油有关。这种情况表明,静脉内甘油给药可以引起短暂的高乳脂血症。