背景：种族化社区，包括加拿大黑人,COVID-19病例比例更高。我们检查了SARS-CoV-2感染对加拿大黑人社区的影响程度以及与感染相关的因素。
方法：我们在安大略省（多伦多西北部/皮尔地区）的一个黑人居民比例较高的地区以及两个黑人居民比例较低的地区（奥克维尔和伦敦，安大略省）。使用EUROIMMUN测定法测定SARS-CoV-2IgG抗体。该研究于2020年8月15日至2020年12月15日进行。
结果：在387名可评估受试者中，大多数,273（70.5%），他们来自多伦多西北部和邻近的皮尔郊区，安大略省。奥克维尔和伦敦的血清阳性值具有可比性（3.3％（2/60；95％CI0.4-11.5）和3.9％（2/51；95％CI0.5-13.5），分别)。相对于这些地区,多伦多西北部/皮尔地区的血清阳性率较高，为12.1%(33/273)，相对风险（RR）3.35（1.22-9.25）。19岁或以下的人血清阳性最高(10/50;20.0%,95%CI10.3-33.7%），RR2.27（1.23-3.59）。种族和居住地之间存在相互作用效应的趋势，因为这与血清阳性的相对风险有关。
结论：在大流行的早期阶段，COVID-19高流行区的血清阳性是安大略省低流行区的三倍.黑人是SARS-CoV-2血清阳性率最高的人之一。
BACKGROUND: Racialized communities, including Black Canadians, have disproportionately higher COVID-19 cases. We examined the extent to which SARS-CoV-2 infection has affected the Black Canadian community and the factors associated with the infection.
METHODS: We conducted a cross-sectional survey in an area of Ontario (northwest Toronto/Peel Region) with a high proportion of Black residents along with 2 areas that have lower proportions of Black residents (Oakville and London, Ontario). SARS-CoV-2 IgG antibodies were determined using the EUROIMMUN assay. The study was conducted between August 15, 2020, and December 15, 2020.
RESULTS: Among 387 evaluable subjects, the majority, 273 (70.5%), were enrolled from northwest Toronto and adjoining suburban areas of Peel, Ontario. The seropositivity values for Oakville and London were comparable (3.3% (2/60; 95% CI 0.4-11.5) and 3.9% (2/51; 95% CI 0.5-13.5), respectively). Relative to these areas, the seropositivity was higher for the northwest Toronto/Peel area at 12.1% (33/273), relative risk (RR) 3.35 (1.22-9.25). Persons 19 years of age or less had the highest seropositivity (10/50; 20.0%, 95% CI 10.3-33.7%), RR 2.27 (1.23-3.59). There was a trend for an interaction effect between race and location of residence as this relates to the relative risk of seropositivity.
CONCLUSIONS: During the early phases of the pandemic, the seropositivity within a COVID-19 high-prevalence zone was threefold greater than lower prevalence areas of Ontario. Black individuals were among those with the highest seroprevalence of SARS-CoV-2.
