Best practice guidelines

最佳实践指南
  • 文章类型: Journal Article
    连续性专业人士协会于2017年首次发布了为成人失禁提供吸收产品的指南。这份共识文件针对的是调试线索,NHS信托委员会,膀胱和肠导联,其中,多年来一直在更新,以确保所有患有节制问题的成年人都接受全面评估,并获得公平的服务。本文概述了2023年2月发布的最新指南。
    The Association for Continence Professionals first published their guidance for the provision of absorbent products for adult incontinence in 2017. This consensus document is targeted towards commissioning leads, NHS Trust Boards, Bladder and Bowel leads, among others, and has been updated over the years to ensure that all adults who suffer with continence issues undergo a comprehensive assessment and have access to an equitable service. This article provides an overview of the latest guidelines which were published in February 2023.
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  • 文章类型: Journal Article
    目标:2018年,发表了最佳实践指南(BPG),用于预防小儿脊柱畸形的错误级别手术,但是尚未成功实施。这项研究的目的是评估BPG发表后5年的依从性。我们假设BPG作者和有更多经验的外科医生的依从性更高,更多的案件,以及对BPG的认识。
    方法:我们询问了北美和欧洲的外科医生,作者和非作者,和儿科脊柱研究小组成员使用由18个李克特量表问题组成的匿名调查对BPG的依从性。受访者提供了多年的实践,每年的案件量,和指导方针意识。通过将Likert反应与MCS得分相关联来得出平均依从性得分(MCS)(\“无时间\”=无依从性=MCS0,\“有时\”=弱到中度=MCS1,\“大多数时间\”=高=MCS2,和\“所有时间\”=完美=MCS3)。
    结果:在134名受访者中,81.5%报告高或完美的依从性。所有指南的平均MCS为2.4±0.4。北美和欧洲的外科医生没有表现出依从性差异(2.4与2.3,p=0.07)。作者和非作者表现出明显不同的依从性评分(2.8vs2.4,p<0.001),有和没有BPG知识的外科医生也是如此(2.5vs2.2,p<0.001)。BPG知晓率与依从性呈中度正相关(r=0.48,p<0.001),依从性与实践年份(r=0.41,p=0.64)和年度病例数(r=0.02,p=0.87)之间无显著关联。
    结论:外科医生报告81.5%的时间使用BPG预防错误级别手术的依从性高或完美。作者身份和BPG意识显示出更高的合规性。位置,研究小组成员,多年的实践,每年的案件量并不影响合规。
    方法:V级专家意见。
    OBJECTIVE: In 2018, Best Practice Guidelines (BPGs) were published for preventing wrong-level surgery in pediatric spinal deformity, but successful implementation has not been established. The purpose of this study was to evaluate BPG compliance 5 years after publication. We hypothesized higher compliance among BPG authors and among surgeons with more experience, higher caseload, and awareness of the BPGs.
    METHODS: We queried North American and European surgeons, authors and nonauthors, and members of pediatric spinal study groups on adherence to BPGs using an anonymous survey consisting of 18 Likert scale questions. Respondents provided years in practice, yearly caseload, and guideline awareness. Mean compliance scores (MCS) were developed by correlating Likert responses with MCS scores (\"None of the time\" = no compliance = MCS 0, \"Sometimes\" = weak to moderate = MCS 1, \"Most of the time\" = high = MCS 2, and \"All the time\" = perfect = MCS 3).
    RESULTS: Of the 134 respondents, 81.5% reported high or perfect compliance. Average MCS for all guidelines was 2.4 ± 0.4. North American and European surgeons showed no compliance differences (2.4 vs. 2.3, p = 0.07). Authors and nonauthors showed significantly different compliance scores (2.8 vs 2.4, p < 0.001), as did surgeons with and without knowledge of the BPGs (2.5 vs 2.2, p < 0.001). BPG awareness and compliance showed a moderate positive correlation (r = 0.48, p < 0.001), with non-significant associations between compliance and both years in practice (r = 0.41, p = 0.64) and yearly caseload (r = 0.02, p = 0.87).
    CONCLUSIONS: Surgeons reported high or perfect compliance 81.5% of the time with BPGs for preventing wrong-level surgery. Authorship and BPG awareness showed increased compliance. Location, study group membership, years in practice, and yearly caseload did not affect compliance.
    METHODS: Level V-expert opinion.
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  • 文章类型: Journal Article
    目的:研究与无ACNP的跨专业团队相比,有急性护理执业护士(ACNP)的跨专业团队对最佳实践指南的遵守程度。
    方法:2023年进行了一项回顾性观察性研究。
    方法:创建了一个回顾性队列,包括280例患者,这些患者在2019年1月1日至2020年1月31日期间接受了冠状动脉旁路移植术和/或瓣膜修复术,并在魁北克(加拿大)大学附属医院的心脏外科病房住院。对最佳实践指南的遵守程度是根据百分比的综合得分来衡量的。综合评分是从一个新开发的工具创建的,该工具包括六个类别的99个项目(患者信息,药物治疗,实验室测试,术后评估,患者和跨专业团队的特点)。计算多元线性和逻辑回归模型,以检查具有ACNP的跨专业团队对遵守最佳实践指南的水平的影响。
    结果:该队列的大多数患者为男性,接受了冠状动脉旁路移植术。与没有ACNP的跨专业团队相比,接受ACNP的跨专业团队护理的患者达到依从性高于80%的可能性是1.72倍,并且在该水平的得分最高四分位数内的可能性是2.29倍。
    结论:本研究提供的经验数据支持ACNP实践对患者的益处,跨专业团队和医疗机构。
    结论:我们的发现确定了跨专业团队的重要贡献,包括使用经过验证的工具的ACNP,以及他们对提供高质量患者护理的贡献。
    本研究遵循加强流行病学观察性研究报告(STROBE)声明:报告观察性研究指南指南。
    没有患者或公众捐款。
    OBJECTIVE: To examine the level of adherence to best-practice guidelines of interprofessional teams with acute care nurse practitioners (ACNPs) compared to interprofessional teams without ACNPs.
    METHODS: A retrospective observational study was conducted in 2023.
    METHODS: A retrospective cohort was created including 280 patients who underwent a coronary artery bypass graft and/or a valve repair and hospitalised in a cardiac surgery unit of a university affiliated hospital in Québec (Canada) between 1 January 2019 to 31 January 2020. The level of adherence to best-practice guidelines was measured from a composite score in percentage. The composite score was created from a newly developed tool including 99 items across six categories (patient information, pharmacotherapy, laboratory tests, post-operative assessment, patient and interprofessional teams\' characteristics). Multivariate linear and logistic regression models were computed to examine the effect of interprofessional teams with ACNPs on the level of adherence to best-practice guidelines.
    RESULTS: Most of the patients of the cohort were male and underwent a coronary artery bypass graft procedure. Patients under the care of interprofessional teams with ACNP were 1.72 times more likely to reach a level of adherence higher than 80% compared to interprofessional teams without ACNPs and were 2.29 times more likely to be within the highest quartile of the scores for the level of adherence to best-practice guidelines of the cohort.
    CONCLUSIONS: This study provides empirical data supporting the benefits of ACNP practice for patients, interprofessional teams and healthcare organisations.
    CONCLUSIONS: Our findings identify the important contributions of interprofessional teams that include ACNPs using a validated instrument, as well as their contribution to the delivery of high quality patient care.
    UNASSIGNED: This study followed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for reporting observational studies guidelines.
    UNASSIGNED: No patient or public contribution.
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  • 文章类型: Journal Article
    背景:MCGR延长已成为治疗EOS患者的一项重要创新。传统种植仪器的替代品,一个单一的外科手术程序是必要的插入结构,其次是非侵入性延长在门诊设置。每一项新技术都会产生新的复杂故障。MCGR未能延长是翻修手术的重要原因。目前,关于如何定义MCGR延长故障,目前尚无共识,未能延长后需要什么步骤,以及什么因素决定了这些后续步骤。这项研究的主要目标是就如何定义和导航未能延长的MCGR达成共识。
    方法:在2021年12月至2022年4月期间,对49名早发性脊柱侧凸外科医生进行了一系列3项调查,其中37项回应。共识被定义为至少70%的协议。
    结果:49名外科医生中有37名(75%)对第一次调查做出了回应,所有37名外科医生都对以下两项调查(100%)做出了回应。关于调查1的25%的问题(3/12),调查2的40%的问题(4/10)和调查3的100%的问题(5/5)达成共识。达成共识的问题详见表1。在办公室中导航无法延长1毫米(97%)的杆的共识步骤包括在同一次访问中重试(78%),改变办公室的技术(88%),并且不调整延长预约的间隔时间(78%)。表1每次调查达成共识的项目(共12项)调查问题答复,共识百分比1如果杆没有拉长,你会在办公室访问中再次尝试吗?78%1确定故障延长时,XR的所有模式都是等效的?是,70%1如果延长不成功,你应该改变延长的间隔时间吗?不,78%2在未能加长杆之后重新加长杆应该改变他们的技术吗?是的,88%复位患者,100%备用棒,90%无牵引力或在连续3次杆未能加长的情况下,MCGR是否不可操作?是的,使用非操作杆确定后续步骤时的考虑因素?骨骼年龄,100%曲线进展,97%曲线刚度,93.8%的家庭便利,83%的时间年龄,从上次延长到77%的时间,70%2APP可以按照您的协议来延长未能延长的杆吗?是的,81%3您是否可以使用笨拙或失速来描述加长时执行器内部离合器失效的现象?是的,97.3%3杂音/失速在调整前重试?是,81%3定义未能加长?达到长度小于1mm,在两次未能延长事件后,你会讨论下一步的手术步骤吗?97%3一旦杆被归类为非操作性(尽管进行了干预,但不再加长),您在做出下一步决定时是否考虑潜在的诊断?是的,97%结论:使用德尔菲法的最佳临床实践指南在定义MCGR(小于1毫米)无法延长方面达成共识,对未能延长(重新尝试延长和重新定位患者)的适当反应和非功能性MCGR(未能连续延长3次)的定义。这一共识将有助于规范对这一重要问题的研究。
    方法:V-专家意见。
    BACKGROUND: MCGR lengthening has become an important innovation in treating patients with EOS. An alternative to traditional growing instrumentation, a single surgical procedure is necessary for insertion of the construct, followed by non-invasive lengthening in the outpatient setting. With every new technology emanates a new complication to troubleshoot. Failure to lengthen in the MCGR is a significant cause of revision surgery. Currently, no consensus exists on how to define a MCGR lengthening failure, what steps are necessary after a failure to lengthen, and what factors determine these next steps. The primary goal of this study was to establish a consensus on how to define and navigate a MCGR that fails to lengthen.
    METHODS: A series of 3 surveys were distributed to 49 early onset scoliosis surgeons with 37 responses between December 2021 and April 2022. Consensus was defined as at least 70% agreement.
    RESULTS: 37 of 49 surgeons (75%) responded to the first survey, and all 37 surgeons responded to the following two surveys (100%). Consensus statements were reached on 25% of questions (3/12) from survey 1, 40% of questions (4/10) on survey 2, and 100% of questions (5/5) on survey 3. The questions that reached consensus are detailed in Table 1. Consensus steps to navigate a rod that fails to lengthen 1 mm (97%) in the office include retrying during the same visit (78%), changing technique in the office (88%), and not adjusting the interval between lengthening appointments (78%). Table 1 Items that reached consensus from each survey (12 total) Survey Question Response, Consensus Percentage 1 If a rod does not lengthen, do you try again in that office visit?​ Yes, 78% 1 All modes of XR are equivalent when determining failure to lengthen? Yes, 70% 1 If you are unsuccessful at lengthening, you should change the lengthening interval? No, 78% 2 Re-lengthening a rod following a failure to lengthen one should change their technique? Yes, 88% Reposition patient, 100% Alternate rods, 90% No traction in OR, 92.6% 2 Is a MCGR non-operational following 3 consecutive visits where the rod failed lengthening? Yes, 100% 2 Considerations when determining next steps with a non-operational rod? Skeletal Age, 100% Curve Progression, 97% Curve Stiffness, 93.8% Family Convenience, 83% Chronologic Age, 77% Time from Last Lengthening, 70% 2 Can an APP follow your protocol for a rod that has failed to lengthen? Yes, 81% 3 Are you comfortable using either clunk or stall to describe the phenomena of the internal clutch failing within the actuator when lengthening? Yes, 97.3% 3 Clunk/stall try again before an adjustment? Yes, 81% 3 Define failure to lengthen? Less than 1 mm length achieved, 97% 3 After two failure to lengthen events do you discuss next surgical steps?​ Yes, 97% 3 Once a rod had been classified as non-operational (no longer lengthening despite interventions) do you consider the underlying diagnosis when making next step decisions? Yes, 97% CONCLUSION: Best clinical practice guidelines using a Delphi method established a consensus on defining failure to lengthen in a MCGR (less than 1 mm), appropriate responses to failure to lengthen (re-attempt to lengthen and re-position patient) and a definition for a non-functional MCGR (failure to lengthen 3 consecutive times). This consensus will help standardize research on this important problem.
    METHODS: V-expert opinion.
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  • 文章类型: Journal Article
    糖尿病相关的足部疾病是糖尿病患者的严重和常见的并发症。与糖尿病相关的足部疾病患者的黄金标准护理是多学科足部团队参与循证护理。迄今为止,有7个糖尿病足国际工作组(IWGDF)指南发布,以协助世界各地的医疗保健提供者管理与糖尿病相关的足部疾病.这篇综述讨论了糖尿病相关足部感染的急性管理,并结合了各种专业专家的见解(内科,传染病,血管手术,放射学),讨论在现实生活中实施IWGDF指南以及医疗保健提供者可能面临的挑战。
    Diabetes-related foot disease is a serious and common complication for people with diabetes mellitus. The gold standard care for a person with diabetes-related foot disease is the involvement of a multidisciplinary foot team engaged in evidence-based care. To date, there are seven International Working Group on the Diabetic Foot (IWGDF) guidelines published to assist healthcare providers in managing diabetes-related foot disease around the world. This review discusses the acute management of diabetes-related foot infection with insights from experts of various specialities (internal medicine, infectious disease, vascular surgery, radiology) with a discussion on the implementation of IWGDF guidelines in real life practice and the challenges that healthcare providers may face.
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  • 文章类型: Journal Article
    目的:十年前发布了最佳实践指南(BPG),旨在减少小儿脊柱畸形的手术部位感染(SSI)。尚未成功实施。这项研究评估了外科医生对BPG项目的依从性。我们假设BPG作者和外科医生有更多的经验,更多的案件,对BPG的认识会有更高的合规性。
    方法:我们询问了北美和欧洲的外科医生,作者和非作者,以及各种脊柱研究小组的成员使用匿名调查对BPG的依从性。通过将Likert反应与MCSs相关联来得出平均依从性得分(MCSs)(\“无时间\”=无依从性=MCS0,\“有时\”=弱到中度=MCS1,\“大多数时间\”=高=MCS2,\“所有时间\”=完美=MCS3)。
    结果:在142名受访者中,73.7%报告高或完美的依从性。所有指南的平均依从性评分为2.2±0.4。北美和欧洲外科医生之间的依从性评分有显著差异(2.3vs1.8,p<0.001),作者和非作者(2.5vs.2.2,p=0.023),以及有和没有BPG知识的外科医生(2.3vs.1.8,p<0.001)。BPG意识与依从性之间存在弱相关性(r=0.34,p<0.001),实践年份(r=0.0,p=0.37)或年病例数(r=0.2,p=0.78)与依从性之间没有相关性。
    结论:我们调查的外科医生队列中的依从性很高。北美外科医生,BPG的作者和那些了解指南的人的依从性提高。参加脊柱研究小组,多年的实践,每年的案件量与合规无关。
    方法:V级专家意见。
    Best Practice Guidelines (BPGs) were published one decade ago to decrease surgical site infection (SSI) in pediatric spinal deformity. Successful implementation has not been established. This study evaluated surgeon compliance with items on the BPG. We hypothesized that BPG authors and surgeons with more experience, higher caseload, and awareness of the BPG would have higher compliance.
    We queried North American and European surgeons, authors and non-authors, and members of various spine study groups on adherence to BPGs using an anonymous survey. Mean compliance scores (MCSs) were developed by correlating Likert responses with MCSs (\"None of the time\" = no compliance = MCS 0, \"Sometimes\" = weak to moderate = MCS 1, \"Most of the time\" = high = MCS 2, \"All the time\" = perfect = MCS 3).
    Of the 142 respondents, 73.7% reported high or perfect compliance. Average compliance scores for all guidelines was 2.2 ± 0.4. There were significantly different compliance scores between North American and European surgeons (2.3 vs 1.8, p < 0.001), authors and non-authors (2.5 vs. 2.2, p = 0.023), and surgeons with and without knowledge of the BPGs (2.3 vs. 1.8, p < 0.001). There was a weak correlation between BPG awareness and compliance (r = 0.34, p < 0.001) and no correlation between years in practice (r = 0.0, p = 0.37) or yearly caseload (r = 0.2, p = 0.78) with compliance.
    Compliance among our cohort of surgeons surveyed was high. North American surgeons, authors of the BPGs and those aware of the guidelines had increased compliance. Participation in a spine study group, years in practice, and yearly caseload were not associated with compliance.
    Level V-expert opinion.
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  • 文章类型: Journal Article
    UNASSIGNED:为了改善患者的治疗效果,许多医疗机构采取了一系列措施来提高护理质量,包括使用循证实践(EBPs),如临床实践指南。然而,对基于指南的实践的长期使用以及如何确保其持续使用几乎没有经验理解。这项研究的目的是确定决定因素和知识翻译干预措施(KTI),从组织的角度来看,随着时间的推移,影响机构疼痛政策和方案的选定建议的持续使用,并在急性护理环境中的两个单位实施10年后。
    UNASSIGNED:我们在实施10年后,以EBP的动态可持续性框架为指导进行了混合方法案例研究。我们检查了加拿大多中心三级护理部门和单位级别的协议可持续性。数据来源包括文件审查(n=29),图表审计(n=200),以及对科室(n=3)和科室(n=16)级别护士的半结构化访谈。
    未经评估:我们确定了32个影响急性护理中持续使用EBP的可持续性决定因素和29个KTI因素。三个决定因素和八个KTI在所有三个时间段都有持续的影响:实施阶段(0-2年),持续阶段(>2-10年。),在十年大关。KTI的实现随着应用级别的发展(例如,部门vs.单元),以使EBP符合上下文,强调需要关注影响持续使用的决定因素。可持续性与持续努力监测和提供有关遵守建议的及时反馈有关。用于将建议嵌入常规实践/过程的KTI对高依从率产生了积极影响。使用参与性方法进行执行和维持,并将旨在逐步解决低遵守率的KTI联系起来,促进了维持。
    UNASSIGNED:这项研究提供了对实施和可持续性决定因素以及实施和持续使用阶段相关KTI之间关系的见解。部门和单位护士确定的独特决定因素反映了他们基于各自的角色和职责对创新的不同观点。KTI促进了急性护理中行为的改变并促进了EBP的维持。研究结果证实,可持续性的概念是一个动态的“持续过程”。\"
    UNASSIGNED: To improve patient outcomes many healthcare organizations have undertaken a number of steps to enhance the quality of care, including the use of evidence-based practices (EBPs) such as clinical practice guidelines. However, there is little empirical understanding of the longer-term use of guideline-based practices and how to ensure their ongoing use. The aim of this study was to identify the determinants and knowledge translation interventions (KTIs) influencing ongoing use of selected recommendations of an institutional pain policy and protocol over time from an organizational perspective and 10 years post implementation on two units within an acute care setting.
    UNASSIGNED: We conducted a mixed methods case study guided by the Dynamic Sustainability Framework of an EBP 10 years post implementation. We examined protocol sustainability at the nursing department and unit levels of a multi-site tertiary center in Canada. Data sources included document review (n = 29), chart audits (n = 200), and semi-structured interviews with nurses at the department (n = 3) and unit (n = 16) level.
    UNASSIGNED: We identified 32 sustainability determinants and 29 KTIs influencing ongoing use of an EBP in acute care. Three determinants and eight KTIs had a continuous influence in all three time periods: implementation phase (0-2 yrs), sustained phase (>2-10 yrs.), and at the 10-year mark. Implementation of KTIs evolved with the level of application (e.g., department vs. unit) to fit the EBP within the context highlighting the need to focus on determinants influencing ongoing use. Sustainability was associated with continual efforts of monitoring and providing timely feedback regarding adherence to recommendations. KTIs used to embed recommendations into routine practices/processes positively influenced high adherence rates. Use of a participatory approach for implementation and sustainment and linking KTIs designed to incrementally address low adherence rates facilitated sustainment.
    UNASSIGNED: This research provides insight into the relationship between implementation and sustainability determinants and related KTIs during implementation and sustained use phases. Unique determinants identified by department and unit nurses reflect their different perspectives toward the innovation based on their respective roles and responsibilities. KTIs fostered changed behaviors and facilitated EBP sustainment in acute care. Findings confirm the concept of sustainability is a dynamic \"ongoing process.\"
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  • 文章类型: Journal Article
    未经评估:作者旨在研究药物滥用和心理健康服务管理局(SAMHSA)最佳实践指南中包含的行为健康危机护理(BHCC)服务的采用。
    UNASSIGNED:使用了2022年SAMHSA行为健康治疗服务定位器的次要数据。BHCC最佳实践以汇总的量表进行测量,以捕获心理健康治疗机构(N=9,385)是否采用BHCC最佳实践,包括向所有年龄组提供这些服务:紧急精神病步入式服务,危机干预小组,现场稳定,移动或非现场危机应对措施,自杀预防,和同行支持。描述性统计数据被用来检查组织特征(如设施运营,type,地理区域,许可证,和支付方式)全国精神卫生治疗设施,并创建了一张地图,以显示最佳实践BHCC设施的位置。进行逻辑回归以确定与采用BHCC最佳实践相关的设施组织特征。
    未经评估:只有6.0%(N=564)的心理健康治疗机构完全采用了BHCC最佳实践。自杀预防是最常见的BHCC服务,由69.8%(N=6,554)的设施提供。移动或异地危机应对服务是最不常见的,采用22.4%(N=2,101)。采用BHCC最佳实践的较高几率与公有制显着相关(调整后的OR[AOR]=1.95),接受自付(AOR=3.18),接受医疗保险(AOR=2.68),并获得任何赠款资金(AOR=2.45)。
    未经批准:尽管SAMHSA指南建议提供全面的BHCC服务,一小部分设施已完全采用BHCC最佳实践。需要努力促进全国广泛采用BHCC最佳做法。
    The authors aimed to examine adoption of behavioral health crisis care (BHCC) services included in the Substance Abuse and Mental Health Services Administration\'s (SAMHSA\'s) best practices guidelines.
    Secondary data from SAMHSA\'s Behavioral Health Treatment Services Locator in 2022 were used. BHCC best practices were measured on a summated scale capturing whether a mental health treatment facility (N=9,385) adopted BHCC best practices, including provision of these services to all age groups: emergency psychiatric walk-in services, crisis intervention teams, onsite stabilization, mobile or offsite crisis responses, suicide prevention, and peer support. Descriptive statistics were used to examine organizational characteristics (such as facility operation, type, geographic area, license, and payment methods) of mental health treatment facilities nationwide, and a map was created to show locations of best practices BHCC facilities. Logistic regressions were performed to identify facilities\' organizational characteristics associated with adopting BHCC best practices.
    Only 6.0% (N=564) of mental health treatment facilities fully adopted BHCC best practices. Suicide prevention was the most common BHCC service, offered by 69.8% (N=6,554) of the facilities. A mobile or offsite crisis response service was the least common, adopted by 22.4% (N=2,101). Higher odds of adopting BHCC best practices were significantly associated with public ownership (adjusted OR [AOR]=1.95), accepting self-pay (AOR=3.18), accepting Medicare (AOR=2.68), and receiving any grant funding (AOR=2.45).
    Despite SAMHSA guidelines recommending comprehensive BHCC services, a fraction of facilities have fully adopted BHCC best practices. Efforts are needed to facilitate widespread uptake of BHCC best practices nationwide.
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  • 文章类型: Journal Article
    硝酸盐(NO3-)的氮和氧的稳定同位素比(15N/14N和18O/16O)是发展对源的系统理解的极好示踪剂,转换,以及反应性大气氮(Nr)在环境中的沉积。尽管最近的分析进展,仍然缺乏降水中NO3-)同位素的标准化采样。为了推进Nr物种的大气研究,我们根据从国际原子能机构(IAEA)协调的国际研究项目中获得的经验,提出了对降水中的NO3-同位素进行准确和精确采样和分析的最佳实践指南。降水采样和保存策略在16个国家的实验室和原子能机构测得的NO3-浓度之间取得了良好的一致性。与传统方法相比(例如,细菌脱氮),我们证实了低成本Ti(III)还原法用于降水样品中NO3-的同位素分析(15N和18O)的准确性能。这些同位素数据描述了无机氮的不同来源和氧化途径。这项工作强调了NO3-同位素评估Nr的起源和大气氧化的能力,并概述了在全球范围内提高实验室能力和专业知识的途径。在未来的研究中建议在Nr中掺入其他同位素如17O。
    Stable isotope ratios of nitrogen and oxygen (15N/14N and 18O/16O) of nitrate (NO3-) are excellent tracers for developing systematic understanding of sources, conversions, and deposition of reactive atmospheric nitrogen (Nr) in the environment. Despite recent analytical advances, standardized sampling of NO3-) isotopes in precipitation is still lacking. To advance atmospheric studies on Nr species, we propose best-practice guidelines for accurate and precise sampling and analysis of NO3- isotopes in precipitation based on the experience obtained from an international research project coordinated by the International Atomic Energy Agency (IAEA). The precipitation sampling and preservation strategies yielded a good agreement between the NO3- concentrations measured at the laboratories of 16 countries and at the IAEA. Compared to conventional methods (e.g., bacterial denitrification), we confirmed the accurate performance of the lower cost Ti(III) reduction method for isotope analyses (15N and 18O) of NO3- in precipitation samples. These isotopic data depict different origins and oxidation pathways of inorganic nitrogen. This work emphasized the capability of NO3- isotopes to assess the origin and atmospheric oxidation of Nr and outlined a pathway to improve laboratory capability and expertise at a global scale. The incorporation of other isotopes like 17O in Nr is recommended in future studies.
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  • 文章类型: Journal Article
    目的:评估电子健康记录(EHR)中基于指南的最佳实践警报(BPA)对遵守美国泌尿外科协会(AUA)膀胱输尿管反流(VUR)指南的影响。
    方法:对0-17岁原发性VUR患者进行回顾性队列研究,并在BPA实施前一年或后一年进行首次泌尿外科门诊就诊。主要结果包括获得生命体征,尿液分析,在初次和1年随访时进行超声检查。
    结果:我们确定了123名在研究期间初次就诊的患者,其中58人返回进行为期1年的随访。BPA后发现的患者比BPA前发现的患者更有可能在初次就诊时测量身高(47.3%vs.11.8%,p<0.001)。在BPA实施前后的1年随访中,大多数患者进行了体重(98.3%)和超声检查(87.9%)。均未测量血压(59.1%与55.6%,p>0.5)尿液分析命令(23.8%与19.4%,p>0.05)显著增加后-BPA。
    结论:使用基于EHR的BPA增加了诊所工作人员获得身高测量的可能性,但没有显著影响提供者对其他实践指南建议的依从性。我们的研究结果表明,仅实施BPA不足以影响提供者对VUR指南建议的采纳。
    OBJECTIVE: To evaluate the effect of a guidelines-based best practice alerts (BPA) in the electronic health record (EHR) on adherence to American Urological Association (AUA) vesicoureteral reflux (VUR) guidelines.
    METHODS: Retrospective cohort study of patients aged 0-17 years old with primary VUR with an initial urology clinic visit the year before or year after BPA implementation was done. Primary outcomes include obtaining vital signs, urinalysis, and ultrasound at initial and 1-year follow-up visit.
    RESULTS: We identified 123 patients with initial visits during the study period, 58 of whom returned for 1-year follow-up visits. Patients seen post-BPA were more likely to have height measured at initial visit than those seen pre-BPA (47.3% vs. 11.8%, p < 0.001). The majority of patients were screened with weight (98.3%) and ultrasound (87.9%) at 1-year follow-up both before and after BPA implementation. Neither blood pressure measurements (59.1% vs. 55.6%, p > 0.5) nor urinalysis orders (23.8% vs. 19.4%, p > 0.05) significantly increased post-BPA.
    CONCLUSIONS: The use of an EHR-based BPA increased the likelihood of obtaining height measurements by clinic intake staff but did not significantly affect provider adherence to other practice guideline recommendations. Our findings suggest that BPA implementation alone is not sufficient to impact provider uptake of VUR guideline recommendations.
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