■文献缺乏用于评估神经肿瘤患者的主要认知领域的简明神经认知测试。本研究旨在描述和评估Ohy-Maldaun快速跟踪认知测试(OMFTCT)的可行性,用于术前和术后评估接受语言雄辩区域脑肿瘤手术的患者。认知诊断用于安全指导术中语言评估。
■这是一项前瞻性纵向观察性临床研究,对50名符合清醒开颅手术条件的神经胶质瘤患者进行。提出的协议评估了多个认知领域,包括语言,短期的言语和视觉记忆,工作记忆,实践,执行功能,和计算能力。协议包括10个不同的子测试,最高得50分,并在三个时间点应用:术前,术后即刻,手术后30天。
■在最初的50名患者中,36在所有三个指定时间点进行了评估。患者平均年龄为45.3岁,他们平均接受了15年的教育。主要的肿瘤类型包括胶质母细胞瘤,IDH-wt(44.1%),弥漫性星形细胞瘤,IDH-突变体(41.2%)。肿瘤位于左侧颞叶(27.8%),其次是左额叶(25%)。完整测试的平均施用时间为23分钟。
■OMFTCT提供了不同认知领域的术前和术后评估,能够更准确地规划术中语言测试。此外,对术后认知障碍的认识在优化患者护理中起着至关重要的作用。
UNASSIGNED: The literature lacks a concise neurocognitive test for assessing primary cognitive domains in neuro-oncological patients. This study aims to describe and assess the feasibility of the Ohy-Maldaun Fast Track Cognitive Test (OMFTCT), used to pre- and post-operatively evaluate patients undergoing brain tumor surgery in language eloquent areas. The cognitive diagnosis was used to safely guide intraoperative language assessment.
UNASSIGNED: This is a prospective longitudinal observational clinical study conducted on a cohort of 50 glioma patients eligible for awake craniotomies. The proposed protocol assesses multiple cognitive domains, including language, short-term verbal and visual memories, working memory, praxis, executive functions, and calculation ability. The protocol comprises 10 different subtests, with a maximum score of 50 points, and was applied at three time points: preoperative, immediately postoperative period, and 30 days after surgery.
UNASSIGNED: Among the initial 50 patients enrolled, 36 underwent assessment at all three designated time points. The mean age of the patients was 45.3 years, and they presented an average of 15 years of education. The predominant tumor types included Glioblastoma, IDH-wt (44.1%), and diffuse astrocytoma, IDH-mutant (41.2%). The tumors were located in the left temporal lobe (27.8%), followed by the left frontal lobe (25%). The full test had an average application time of 23 min.
UNASSIGNED: OMFTCT provided pre- and postoperative assessments of different cognitive domains, enabling more accurate planning of intraoperative language testing. Additionally, recognition of post-operative cognitive impairments played a crucial role in optimizing patient care.