■研究表明,患有帕金森病(PwPs)的人可能会在周围和中枢听觉处理方面遇到挑战,尽管研究结果不一致。由于使用的听觉测量的多样性,需要标准化,可复制的听力评估,以澄清试听的哪些方面在PWP中受到影响,以及它们是否与运动和非运动症状有关。
■表征听觉过程及其在PwPs中可能的变化。为了解决这个问题,我们使用PART收集了一套全面的标准化试听措施,旨在促进复制的数字测试平台。此外,我们研究了听觉之间的关系,认知,和PwPs中的临床变量。
■我们包括44名PwPs和54名年龄和教育匹配的健康对照。评估包括检测二分和二分调频,时间间隙,光谱-时间宽带调制,和语音掩蔽。
■我们发现PwPs和对照组之间的听觉处理措施没有统计学上的显着差异(ps>0.07)。在PwPs中,听觉处理综合评分显示与认知测量值(0.39■虽然需要更大的数据集来澄清PwPs是否比健康对照经历更多的听觉困难,我们的结果强调了使用标准化可复制方法对帕金森病症状谱进行听觉处理的重要性.
目前尚不清楚帕金森病(PD)与听力之间是否存在关系。虽然一些研究发现听力障碍与PD有关,其他研究未能复制这些效应.我们认为,这些不同发现的可能原因是听力测量方式的差异。为了澄清文献,我们使用免费提供的基于平板电脑的应用程序,对一组帕金森氏症(PwPs)患者的听力进行了测试。我们将PwPs听力测试与年龄和教育程度相匹配的无PD人群进行了比较。虽然我们发现各组之间没有明显差异,我们确实发现更好的听力与运动症状严重程度和抑郁症有关,更好的生活质量报告,和较少报告的负担的疾病经历的看护。我们得出的结论是,虽然没有确凿的证据表明PD的听力一定会受损,测量PwPs的听力可以提供有价值的临床信息。这可以为患有PD的人提供新的治疗方法,例如与改善听力有关的方法。
UNASSIGNED: Research indicates that people with Parkinson\'s disease (PwPs) may experience challenges in both peripheral and central auditory processing, although findings are inconsistent across studies. Due to the diversity of auditory measures used, there is a need for standardized, replicable hearing assessments to clarify which aspects of audition are impacted in PWPs and whether they are linked to motor and non-motor symptoms.
UNASSIGNED: To characterize auditory processes and their possible alteration in PwPs. To address this, we collected a comprehensive set of standardized measures of audition using PART, a digital testing platform designed to facilitate replication. Additionally, we examined the relationship between auditory, cognitive, and clinical variables in PwPs.
UNASSIGNED: We included 44 PwPs and 54 age and education matched healthy controls. Assessments included detection of diotic and dichotic frequency modulation, temporal gaps, spectro-temporal broad-band modulation, and speech-on-speech masking.
UNASSIGNED: We found no statistically significant differences in auditory processing measures between PwPs and the comparison group (ps > 0.07). In PwPs, an auditory processing composite score showed significant medium size correlations with cognitive measures (0.39 < r<0.41, ps < 0.02) and clinical variables of motor symptom severity, quality of life, depression, and caretaker burden (0.33 < r<0.52, ps < 0.03).
UNASSIGNED: While larger datasets are needed to clarify whether PwPs experience more auditory difficulties than healthy controls, our results underscore the importance of considering auditory processing on the symptomatic spectrum of Parkinson\'s disease using standardized replicable methodologies.
It is unknown whether there exists a relationship between Parkinson’s disease (PD) and hearing ability. While some studies have found hearing difficulties to be associated with PD, other studies failed to replicate these effects. We suggest that a possible reason for these differing findings are differences in how hearing is measured. To clarify the literature, we tested a group of people with Parkinson’s (PwPs) on several aspects of hearing using a freely available tablet-based app. We compared PwPs hearing tests to those of an age and education matched group of people without PD. While we found no clear differences among the groups, we did find better hearing abilities were related to less motor symptom severity and depression, better reported quality of life, and less reported burden of the disease experienced by the caretaker. We conclude that while there is no solid evidence showing the hearing is necessarily impaired in PD, that measuring hearing in PwPs can provide valuable clinical information. This can inform new approaches to treatment for people living with PD such as those related with improving hearing.