目标:为了描述其基本原理,设计,STEEER-AF的给药和基线特征(卒中预防和节律控制治疗:一项针对心房颤动患者的欧洲心脏病学会[ESC]的教育计划的评估).
结果:STEEER-AF是一项务实的试验,旨在客观而有力地确定常规实践中是否遵守指南,并评估针对医疗保健专业人员的有针对性的教育计划。在6个国家随机分配了70个中心(法国,德国,意大利,波兰,西班牙和英国;2022-2023年)。STEEER-AF中心招募了1732名诊断为房颤(AF)的患者,平均年龄68.9岁(SD11.7),CHA2DS2-VASc评分3.2(SD1.8)和647(37%)女性。843例(49%)房颤患者和760例(44%)窦性心律患者。1,543例患者(89%)进行了口服抗凝治疗,大多数接受直接口服抗凝药(1,378;89%)。以前的心脏复律,836例患者(48.3%)接受抗心律失常药物治疗或消融治疗.551名患者(31.8%)目前正在接受抗心律失常药物,446例(25.8%)计划接受未来的心脏复律或消融.该教育计划邀请了195名医疗专业人员,这些专业人员随机分配到干预组,由定制的交互式在线学习和强化活动组成,由国家专家培训师支持。
结论:STEEER-AF试验成功部署在六个欧洲国家,以调查现实世界实践中的指南依从性。并评估针对医疗保健专业人员的结构化教育计划是否可以改善患者级别的护理。
背景:Clinicaltrials.govNCT04396418。
OBJECTIVE: To describe the rationale, design, delivery and baseline characteristics of STEEER-AF (Stroke prevention and rhythm control Treatment: Evaluation of an Educational programme of the European Society of Cardiology [ESC] in a cluster-Randomised trial in patients with Atrial Fibrillation).
RESULTS: STEEER-AF is a pragmatic trial designed to objectively and robustly determine whether guidelines are adhered to in routine practice, and evaluate a targeted educational programme for healthcare professionals. Seventy centres were randomised in 6 countries (France, Germany, Italy, Poland, Spain and United Kingdom; 2022-2023). STEEER-AF centres recruited 1732 patients with a diagnosis of atrial fibrillation (AF), with mean age 68.9 years (SD 11.7), CHA2DS2-VASc score 3.2 (SD 1.8) and 647 (37%) women. 843 patients (49%) were in AF and 760 (44%) in sinus rhythm at enrolment. Oral anticoagulant therapy was prescribed in 1,543 patients (89%), with the majority receiving direct oral anticoagulants (1,378; 89%). Previous cardioversion, antiarrhythmic drug therapy or ablation was recorded in 836 patients (48.3%). 551 patients (31.8%) were currently receiving an antiarrhythmic drug, and 446 (25.8%) were scheduled to receive a future cardioversion or ablation. The educational programme engaged 195 healthcare professionals across centres randomised to the intervention group, consisting of bespoke interactive online learning and reinforcement activities, supported by national expert trainers.
CONCLUSIONS: The STEEER-AF trial was successfully deployed across six European countries to investigate guideline adherence in real-world practice, and evaluate if a structured educational programme for healthcare professionals can improve patient-level care.
BACKGROUND: Clinicaltrials.gov NCT04396418.