登革热是一个主要的公共卫生问题。随着有效疫苗的开发,确定最大限度地提高登革热疫苗吸收的动机因素很重要。横截面,定量,对阿根廷具有全国代表性的成年人(n=3800)进行了电子调查,巴西,哥伦比亚,墨西哥,印度尼西亚,马来西亚,和新加坡。愿意接种登革热疫苗,和知识,态度,和做法(KAP)对登革热,矢量控制,预防,并确定了疫苗接种。能力,机会,行为改变动机(COM-B)框架用于鉴定与登革热疫苗摄取相关的因素。KAP分数(标准化,0-100%量表)导致知识(48%)和实践(44%)的全球得分较低,态度得分中等(66%);各国得分相当。在所有受访者中,53%的人有很高的意愿(得分:8-10/10)接种登革热疫苗,这一比例在拉丁美洲更高(59%)(阿根廷,巴西,哥伦比亚,墨西哥)比亚太地区(40%)(印度尼西亚,马来西亚,新加坡)。与疫苗接种意愿增加相关的关键因素(p<0.05)包括公众的可及性(补贴和激励措施)以及对医疗保健系统和政府的信任。流行国家预防登革热的通用方法-具有一些特定国家的定制,包括教育,疫苗接种,和媒介控制(多管齐下)-可以减轻登革热负担并改善结果。
Dengue represents a major public health concern. With effective vaccines in development, it is important to identify motivational factors to maximize dengue vaccine uptake. A cross-sectional, quantitative, electronic survey was administered to a nationally representative adult population (n = 3800) in Argentina, Brazil, Colombia, Mexico, Indonesia, Malaysia, and Singapore. Willingness to vaccinate against dengue, and Knowledge, Attitudes, and Practices (KAP) toward dengue, vector control, prevention, and vaccination were determined. The Capability, Opportunity, Motivation for Behavior change (COM-B) framework was used to identify factors correlated with dengue vaccine(s) uptake. KAP scores (standardized, 0-100% scale) resulted in a low global score for Knowledge (48%) and Practice (44%), and a moderate score for Attitude (66%); scores were comparable across countries. Of all respondents, 53% had a high willingness (Score: 8-10/10) to vaccinate against dengue, which was higher (59%) in Latin America (Argentina, Brazil, Colombia, Mexico) than in Asia Pacific (40%) (Indonesia, Malaysia, Singapore). Key factors significantly (p < 0.05) associated with increased willingness to vaccinate included accessibility to the public (subsidies and incentives) and trust in the healthcare system and government. A common approach to dengue prevention across endemic countries--with some country-specific customization, including education, vaccination, and vector control (multi-pronged)--may reduce dengue burden and improve outcomes.