抑郁症和脑震荡是非常普遍的神经心理障碍,通常同时发生。然而,由于两个事件之间的高度症状重叠,包括但不限于头痛,睡眠障碍,食欲变化,疲劳,难以集中注意力,他们可以单独治疗。因此,临床对附加症状负荷的认识可能被遗漏。这项研究测量了患有抑郁症和脑震荡的大学学生运动员的神经心理学和脑电图(EEG)α带相干性差异,与具有单一发病率和健康对照(HC)的患者相比。35名大学运动员完成了神经心理筛查和脑电图检查。参与者按脑震荡和抑郁病史分组。使用双向ANOVA计算α带相干性的差异,并对多重比较进行事后校正。合并者在神经心理学筛查中得分明显更差,BDI-FS,和PCSS比那些具有单一发病率和HC。分组的双向方差分析揭示了α带相干性对脑震荡的显著主要影响,抑郁症,和他们的互动术语。事后分析表明,共病参与者比单一发病率有更多的异常α带相干性,与HC相比。与单一发病率相比,脑震荡和抑郁症的合并症增加了症状报告,并显示出更多的α带相干性改变。与HC相比。与健康对照组相比,共病组的异常仅显示α带相干性降低。抑郁症和SRC的共病对抑郁症状具有复合作用,脑震荡后的症状,和大脑功能连接。这项研究在合并症个体中证明了一种有希望的客观措施,以前只能通过主观症状报告进行测量。
Depression and concussion are highly prevalent neuropsychological disorders that often occur simultaneously. However, due to the high degree of symptom overlap between the two events, including but not limited to headache, sleep disturbances, appetite changes, fatigue, and difficulty concentrating, they may be treated in isolation. Thus, clinical awareness of additive symptom load may be missed. This study measures neuropsychological and electroencephalography (EEG) alpha band coherence differences in collegiate student-athletes with history of comorbid depression and concussion, in comparison to those with a single morbidity and healthy controls (HC). 35 collegiate athletes completed neuropsychological screenings and EEG measures. Participants were grouped by concussion and depression history. Differences in alpha band coherence were calculated using two-way ANOVA with post hoc correction for multiple comparisons. Comorbid participants scored significantly worse on neuropsychological screening, BDI-FS, and PCSS than those with a single morbidity and HC. Two-way ANOVA by group revealed significant main effects of alpha band coherence for concussion, depression, and their interaction term. Post-hoc analysis showed that comorbid participants had more abnormal alpha band coherence than single morbidity, when compared to HC. Comorbidity of concussion and depression increased symptom reporting and revealed more altered alpha band coherence than single morbidity, compared to HC. The abnormalities of the comorbid group exclusively showed decreased alpha band coherence in comparison to healthy controls. The comorbidity of depression and SRC has a compounding effect on depression symptoms, post-concussion symptoms, and brain functional connectivity. This research demonstrates a promising objective measure in comorbid individuals, previously only measured via subjective symptom reporting.