背景:中低收入国家的慢性肾脏病(CKD)前景不佳。尼日利亚的现代农业做法与除草剂和杀虫剂的使用越来越相关。
目的:该研究旨在评估尼日利亚西南部农村农业社区居民在农业实践中使用农用化学品以及肾脏疾病的危险因素。
方法:这是对尼日利亚西南部农村农业社区成年居民的横断面调查。与会者提供了人口统计信息,生活方式,知识,以及对肾病危险因素的认识,以及农业化学品在农业实践中的使用。人体测量和血压值,同时收集血液和斑点尿液进行随机血糖,血清肌酐,尿液分析,和白蛋白肌酐比.
结果:共有572名农村居民参加了这项研究,平均年龄为49.9±17.5岁,男性占39.3%,从事积极农业的占88.9%。肾脏病的传统危险因素患病率为高血压(24.3%),糖尿病(2.8%),吸烟(7.5%),酒精摄入量(20.8%)和草药消费量(57.1%)。杀虫剂/除草剂的使用量占69.9%,25.3%的人在使用过程中没有使用防护装备。蛋白尿,血尿,并在29.8%观察到eGFR降低,6.1%,33.9%的参与者,分别。
结论:这项研究表明,除草剂和农药使用以及肾脏疾病的传统危险因素的患病率很高,此外,在尼日利亚西南部农村农业聚居区的居民中,肾脏损害标志物的患病率很高。
BACKGROUND: The outlook of chronic kidney disease (CKD) in low-and-medium-income-countries is poor. Modern farming practices in Nigeria are becoming increasingly associated with the use of herbicides and pesticides.
OBJECTIVE: The study aimed to evaluate agrochemical use in farming practices and risk factors for kidney disease among dwellers of rural farming communities in South-West Nigeria.
METHODS: This was a cross-sectional survey of adult dwellers of an agrarian rural farming community in South-West Nigeria. Participants provided information on demographics, lifestyles, knowledge, and awareness of risk factors for kidney disease, and the use of
agrochemicals in farming practice. Anthropometric measurements and blood pressure values were obtained while blood and spot urine were collected for random blood glucose, serum creatinine, urinalysis, and albumin-creatinine ratio.
RESULTS: A total of 572 rural dwellers were enrolled in the study, with a mean age of 49.9 ± 17.5 years while 39.3% were male and 88.9% engaged in active farming. The prevalence of traditional risk factors for kidney disease was hypertension (24.3%), Diabetes mellitus (2.8%), cigarette smoking (7.5%), alcohol intake (20.8%) and herbal consumption (57.1%). The use of pesticides/herbicides was reported in 69.9%, while 25.3% did not use protective gear during its use. Proteinuria, hematuria, and reduced eGFR were observed in 29.8%, 6.1%, and 33.9% of participants, respectively.
CONCLUSIONS: This study showed a high prevalence of herbicides and pesticide use and traditional risk factors for kidney disease, in addition to the high prevalence of markers of kidney damage among the dwellers of rural farming settlements in South-West Nigeria.