Agenesis

发育不良
  • 文章类型: Case Reports
    颈内动脉(ICA)的发育不全或发育不全很容易与夹层或闭塞相混淆。我们报告了一例24岁的女性,主诉急性左手感觉减退,并且偶尔有右手间歇性麻木并伴有肌阵挛性抽搐的病史。因为过去2年的影像学研究被解释为继发于颈动脉夹层的左侧ICA闭塞,主治医生开了抗凝治疗.经颅多普勒(TCD)检查期间,频谱波形出乎意料地正常,由于TCD结果,提示重复检查所有影像学检查。磁共振血管造影(MRA)显示ICA起源具有相同的“火焰状”外观。后期数字减影血管造影显示小口径颈部ICA(颅底闭塞)。计算机断层扫描显示没有颈动脉,确认ICA的颅内部分缺失,并正确诊断左侧颈内动脉发育不全。血管超声和TCD检查是非侵入性和廉价的工具,可以提高对其他“静态”影像学检查(MRA,数字减影血管造影)。准确的诊断对于避免风险至关重要,积极治疗,如“无”夹层的抗凝治疗。
    Agenesis or hypoplasia of the internal carotid artery (ICA) may easily be confused with dissection or occlusion. We report a case of a 24-year-old female with complaint of acute left-hand hypoesthesia and a history of occasional intermittent numbness of her right hand with myoclonic jerking. Because previous imaging studies over 2 years were interpreted as occlusion of the left ICA secondary to carotid dissection, the treating physician had prescribed anticoagulant therapy. During transcranial Doppler (TCD) examination, the spectral waveform was unexpectedly normal, prompting a repeat review of all imaging due to the TCD results. Magnetic resonance angiography (MRA) revealed the same \"flame-like\" appearance of the ICA origin. Late-phase digital subtraction angiography showed a small caliber cervical ICA (occluded at the skull base). Computed tomography demonstrated absence of the carotid canal, confirming an absent intracranial portion of the ICA and establishing a correct diagnosis of left internal carotid hypoplasia. Vascular ultrasound and TCD examinations are noninvasive and inexpensive tools that can improve the interpretation and understanding of the clinical significance of other \"static\" radiographic tests (MRA, digital subtraction angiography ). An accurate diagnosis is essential to avoid risky, aggressive treatment, such as anticoagulation for an \"absent\" dissection.
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  • 文章类型: Journal Article
    这项研究的目的是发现印度年轻人群中第三磨牙发育不全的患病率。
    进行了横断面研究,包括21世纪出生的年轻人口(13-21岁)。需要正像图的人,无论出于什么原因,在研究中被招募。
    研究了850个正相图,298例(35.05%)个体显示至少1个或更多个第三磨牙的发育不全。最常见的发育不全模式是两个上颌第三磨牙的缺失,其次是所有第三磨牙的发育不全。发育频率为18>28>48>38。研究表明,与下颌骨相比,上颌骨有明显的优势。第三磨牙发育不全的性别倾向无统计学意义。
    第三磨牙发育不全的患病率随时间迅速增加,没有明显的性别偏好和发育不良模式的变化趋势。
    UNASSIGNED: The objective of this study was to find the prevalence of agenesis of third molar among the younger population of India.
    UNASSIGNED: A cross-sectional study was conducted, and a younger population (13-21 years) born in the twenty-first century were included. Individuals who required an orthopantomogram, for any reason, were recruited in the study.
    UNASSIGNED: A total number of 850 orthopantomograms were studied, and 298 (35.05%) individuals showed the agenesis of at least 1 or more third molars. The most common pattern of agenesis was the missing of both maxillary third molars, followed by the agenesis of all third molars. The frequency of agenesis was 18 >28 >48 >38. The study showed a significant predilection in the maxilla as compared to the mandible. There was no statistically significant gender predilection for agenesis of third molar.
    UNASSIGNED: The prevalence of third molar agenesis is increasing rapidly with time, with no significant gender predilection and changing trends of patterns of agenesis.
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  • 文章类型: Journal Article
    此案例研究旨在阐明双侧颈内动脉发育不全合并牛主动脉弓的罕见情况。主要目标是探索发病率,胚胎学起源,临床表现,以及这种独特血管疾病的相关异常。该研究涉及使用MRI和CT扫描对一名55岁有复发性短暂性脑缺血发作(TIA)病史的男性进行详细调查。病人的病史,临床检查,和成像结果进行了系统分析,以提供解剖变异的透彻理解。主要发现包括双侧ICA发育不全和牛主动脉弓的罕见共存,这是第39次记录的双侧ICA发育不全的发生,也是第一次记录的与牛主动脉弓相关的实例。此外,这项研究强调了人口统计学特征,临床表现,以及在38例记录的双侧颈内动脉发育不全病例中观察到的相关异常。此病例报告为双侧颈内动脉发育不全的稀有性及其与牛主动脉弓的空前关联提供了宝贵的见解。研究结果强调了在临床实践中提高解剖学意识的重要性。尤其是。认识和理解这种变化对于准确诊断至关重要。适当的管理,改善患者预后。有必要在这一领域进行进一步的研究,以加深我们对这些复杂血管异常的理解。
    This case study aims to elucidate the rare occurrence of bilateral internal carotid artery agenesis combined with a bovine aortic arch. The main objectives are to explore the incidence, embryological origins, clinical manifestations, and associated anomalies of this unique vascular condition. The study involves a detailed investigation of a 55-year-old male with a history of recurrent transient ischemic attacks (TIAs) using MRI and CT scan. The patient\'s medical history, clinical examination, and imaging results were systematically analyzed to provide a thorough understanding of the anatomical variations. The main findings include the rare coexistence of bilateral ICA agenesis and a bovine aortic arch, making this the 39th documented occurrence of bilateral ICA agenesis and the first recorded instance of its association with a bovine aortic arch. Also, the study highlighted the demographic characteristics, clinical presentations, and associated anomalies observed in the 38 documented cases of bilateral internal carotid artery agenesis. This case report contributes valuable insights into the rarity of bilateral internal carotid artery agenesis and its unprecedented association with a bovine aortic arch. The findings emphasize the importance of heightened anatomical awareness in clinical practice, particularly. Recognizing and understanding such variations is crucial for accurate diagnosis, appropriate management, and improved patient outcomes. Further research in this area is warranted to deepen our understanding of these complex vascular anomalies.
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  • 文章类型: Case Reports
    左肝叶的分裂是一种罕见的异常,被描述为胆囊窝或镰状韧带左侧没有肝组织。在这里,我们报告了在84岁的男性福尔马林固定尸体的教育解剖过程中发现的左肝叶发育不全的病例。大体解剖特征,胚胎学起源,本报告描述了这种罕见变异的临床相关性。
    Agenesis of the left hepatic lobe is a rare anomaly described as the absence of liver tissue on the left side of the gallbladder fossa or falciform ligament. Here we report a case of agenesis of the left hepatic lobe identified during educational dissection of an 84-year-old male formalin-fixed cadaver. The gross anatomical characteristics, embryological origin, and clinical relevance of this rare variation are described in this report.
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  • 文章类型: Case Reports
    目的:报告一例颈内动脉(ICA)发育不全的李氏A型和D型合并病例,通过磁共振血管造影(MRA)诊断。
    方法:一名患有头晕的60岁女性患者接受了头颅磁共振成像(MRI)和颅内区域的MRA,以评估脑和血管病变。磁共振机是3.0-T扫描仪。
    结果:MRI显示无异常,除了多发性小白质病变。MRA显示左ICA不在,除了上面骨段,双侧ICA的突突旁段之间存在吻合血管,表示Lie的D型ICA。还存在左后交通动脉(PCoA)。因此,也有A型ICA发育不全的特征。双侧ICA和同侧PCoA之间的吻合血管口径相对较小。
    结论:李氏D型ICA发育不全通常与前后循环不连通。我们遇到了一例D型和A型ICA联合发育不全。据我们所知,英文文献中没有类似病例的报道.这是第二例具有同侧PCoA专利的D型ICA发育不全。我们推测,在A型ICA发育不全的情况下,当PCoA的发育不足以支持侧支血流时,双侧ICA之间可能形成吻合血管。
    OBJECTIVE: To report an unusual case of combined Lie\'s types A and D of internal carotid artery (ICA) agenesis, diagnosed by magnetic resonance angiography (MRA).
    METHODS: A 60-year-old woman with dizziness underwent cranial magnetic resonance imaging (MRI) and MRA of the intracranial region for the evaluation of brain and vascular lesions. The magnetic resonance machine was a 3.0-T scanner.
    RESULTS: MRI showed no abnormalities, except for multiple small white matter lesions. MRA showed that the left ICA was absent, except for the supraclinoid segment, and an anastomotic vessel was present between the paraclinoid segments of the bilateral ICAs, indicating Lie\'s type D ICA agenesis. The left posterior communicating artery (PCoA) was also present. Thus, there were also features of type A ICA agenesis. The anastomotic vessels between the bilateral ICAs and ipsilateral PCoA were relatively small in caliber.
    CONCLUSIONS: Lie\'s type D ICA agenesis usually does not communicate with the anterior and posterior circulations. We encountered a case of combined type D and type A ICA agenesis. To our knowledge, no similar case has been reported in the English literature. This is the second case of type D ICA agenesis with patent ipsilateral PCoA. We speculate that in case of type A ICA agenesis, when the development of the PCoA is insufficient to support collateral blood flow, an anastomotic vessel between bilateral ICAs may develop.
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  • 文章类型: Journal Article
    背景:牙科异常模式(DAP)是一个形态学的集合,数值,和经常一起观察到的牙齿喷发异常,暗示了潜在的遗传关系。我们的目的是评估磨牙切牙低矿化(MIH)的潜在关联,一种常见的牙釉质矿化发育缺陷,病因有争议,具有DAP的两个特定成分:(1)发育不全(AG)和(2)下颌落叶磨牙(IODM)。在MIH与一个或两个异常之间建立这种关联将提供支持MIH与DAP之间遗传联系的证据。方法:我们检查了574名8-14岁儿童的口腔内标准化照片和全景X射线照片,具有MIH的287和没有MIH的287,比较两组中AG和IODM的频率。受试者样品来自大学医院正畸科的数据库。结果:MIH组和非MIH组的AG频率分别为7%和8%,分别(p=0.751)。IODM的相应频率分别为27%和19.2%,分别(p=0.082)。也就是说,与没有MIH的儿童相比,患有MIH的儿童AG或IODM的频率没有增加.结论:这些发现不支持将MIH纳入DAP。然而,有必要对可能的关联进行进一步分析,以明确验证或使这一假设无效.
    Background: Dental Anomaly Pattern (DAP) is a collection of morphologic, numeric, and eruptive anomalies of teeth that are often observed together, suggesting a potential genetic relationship. Our objective was to assess the potential associations of Molar-Incisor Hypomineralization (MIH), a common developmental defect of enamel mineralization with a controversial etiology, with two specific components of DAP: (1) agenesis (AG) and (2) infraoccluded deciduous molars (IODM). Establishing such an association between MIH and one or both anomalies would provide evidence supporting a genetic link between MIH and DAP. Methods: We examined pretreatment intraoral standardized photographies and panoramic radiographs from 574 children aged 8-14 years, 287 having MIH and 287 without MIH, comparing the frequencies of AG and IODM in both groups. The subject samples were sourced from the databases of the orthodontic department at a university hospital. Results: The frequencies of AG in the MIH and non-MIH groups were 7% and 8%, respectively (p = 0.751). The corresponding frequencies of IODM were 27% and 19.2%, respectively (p = 0.082). That is, children with MIH did not exhibit an increased frequency of AG or IODM compared to those without MIH. Conclusions: These findings do not support the inclusion of MIH in DAP. Nevertheless, further analysis of possible associations is necessary to definitively validate or invalidate this hypothesis.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    这项回顾性研究旨在确定先天性下颌第二前磨牙缺失的患病率。
    总共从巴勒斯坦的五个不同城市收集了1,843张X射线照片。两名经验丰富的牙医独立检查了全景射线照片和人口统计数据(年龄和性别)。
    在1,843张射线照片中,女性1,039例(57.37%),男性804例(43.63%);13例至少有一个先天性下颌第二前磨牙。研究人群中先天性下颌第二前磨牙缺失的患病率为0.7%。性别与下颌第二前磨牙发育不全之间没有显着关联。单侧发育不全比双侧发育不全更常见,左侧先天性下颌第二前磨牙缺失的病例多于右侧。
    本研究人群中先天性下颌第二前磨牙缺失的患病率为0.7%,在其他人群报告的范围内。
    UNASSIGNED: This retrospective study aimed to determine the prevalence of congenitally missing mandibular second premolars.
    UNASSIGNED: A total of 1,843 radiographs were collected from five different cities in Palestine. Two experienced dentists independently examined the panoramic radiographs and demographic data (age and gender).
    UNASSIGNED: Among the 1,843 radiographs, 1,039 were for females (57.37%) and 804 were for males (43.63%); 13 cases had at least one congenitally mandibular second premolar. The prevalence of congenitally missing mandibular second premolars in the study population was 0.7%. There was no significant association between gender and mandibular second premolar agenesis. Unilateral agenesis was more common than bilateral, and the left side had more cases of congenitally missing mandibular second premolars than the right side.
    UNASSIGNED: The prevalence of congenitally missing mandibular second premolars in this study population was 0.7%, within the range reported in other populations.
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  • 文章类型: Journal Article
    随着现代成像技术的广泛使用,越来越多地发现了胰腺的先天性变异。潜在的胚胎学畸变预测胰腺发育的最终外观。必须认识到这些先天性变异,因为其中许多已被证明与胰腺疾病有关,例如复发性胰腺炎和慢性腹痛。诸如多探测器计算机断层扫描和磁共振胰胆管成像之类的横截面技术是胰腺最常用的成像技术,放射科医生发现了这些变异。该图片旨在对胰腺的变异解剖类型进行分类,他们的成像外观,及其临床意义。
    Congenital variants of the pancreas are being increasingly detected with the widespread use of modern imaging techniques. The underlying embryologic aberration predicts the final appearance of pancreatic development. It is essential to recognize these congenital variants, as many of these have been proven to be associated with pancreatic diseases like recurrent pancreatitis and chronic abdominal pain. Cross-sectional techniques like multidetector computed tomography and magnetic resonance cholangiopancreatography are the most used imaging techniques for the pancreas, where a radiologist comes across these variants. This pictorial aims to classify the type of variant anatomy of the pancreas, their imaging appearances, and their clinical significance.
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  • 文章类型: Journal Article
    影响同一手内多个屈肌肌腱的发育不全和发育不全代表了非常罕见的发生,以前没有研究解决这种情况。这份报告详细介绍了一个4岁的女孩,右第三和第四手指发育不全,由于无法弯曲她看似未受影响的第二和第五根手指而寻求咨询。超声检查显示屈肌肌腱在第二至第五位明显变薄,明显没有附着在中间指骨上。除了屈肌腱发育不全,观察到第三和第四中间指骨发育不全。手指发育不全和多个手指的屈肌腱发育不全的手部畸形极为罕见。在这种情况下,超声,结合射线照相,作为推荐的初始成像工具,用于全面评估指骨和屈肌腱。
    Agenesis and hypoplasia affecting multiple flexor tendons within the same hand represent an exceedingly uncommon occurrence, with no previous studies addressing this condition. This report details a 4-year-old girl with agenesis of the right third and fourth fingers, who sought consultation due to the inability to flex her seemingly unaffected second and fifth fingers. Ultrasound examination revealed substantial thinning of the flexor tendons in the second to fifth digits, with a notable absence of attachment to the middle phalanx. In addition to flexor tendon hypoplasia, hypoplasia of the third and fourth middle phalanges was observed. Hand deformities featuring both finger agenesis and flexor tendon hypoplasia across multiple fingers were exceptionally rare. In such instances, ultrasound, in conjunction with radiography, emerges as the recommended initial imaging tool for comprehensive evaluation of both the phalangeal bones and flexor tendons.
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