Age determination

年龄确定
  • 文章类型: Journal Article
    Identification of a person by general group characteristics does not lose its relevance over a long period. An analysis of publications (2000-2023) devoted to the possibilities of using the sternum to determine gender and age showed a fairly large amount of work on this topic, with very promising results. The trend in the development of this area is the use of modern methods of medical imaging. This becomes the starting point for conducting such studies on the territory of the Russian Federation and developing a methodology that includes the Russian population, taking into account their population characteristics.
    Отождествление личности по общегрупповым признакам не теряет актуальности на протяжении длительного периода. Анализ публикаций (2000—2023), посвященных возможностям использования грудины для установления пола и возраста, показал достаточно большой объем наработок по данной тематике с перспективными итогами. Тренд развития этого направления — использование современных методов медицинской визуализации — становится отправной точкой для проведения подобных исследований на территории Российской Федерации с целью разработки методики опознания неустановленного лица с учетом популяционных особенностей российского населения.
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  • 文章类型: Journal Article
    镭三重态226Ra的浓度增加,228Ra和224Ra是例如在地热装置中使用的高盐水缺氧深水的经常观察到的性质。在本研究中,我们开发了一个模型来解释盐水中观察到的活性水平。该模型考虑了含水层岩石-流体界面的过程,如α反冲,吸附和表面沉淀,并通过蒙特卡罗模拟实现。模拟结果表明,储层岩石的细粒成分具有主导作用,例如,具有增强的自然腐烂链的特定活动的粘土石。这种材料的质量分数在几个百分比的量级足以导致镭流体浓度>1Bql-1。还发现了含水层岩石中的Th/U比与流体中的228Ra/226Ra活度比之间的普遍有效关系。这种联系改善了镭流体数据与地壳平均Th/U比之间的一致性。224Ra/228Ra流体比率反映了从最后一次镭释放的位置到采样点的传输时间。模型结果已应用于北德盆地地热工厂中使用的经过充分调查的含水层。建立了含水层岩石的八组分系统,作为模拟深层流体中镭浓度的基础。模拟和流体分析之间的比较显示,镭的吸附程度约为50%,这是使模型的结果与测量结果匹配所必需的。另一方面,模拟结果很好地再现了盐水的228Ra/226Ra流体比,表明该模型即使在复杂非均质储层中也具有适用性。根据224Ra/228Ra流体比,建议从孔隙到裂缝引导传输的过渡距离生产井<10m。在热力学条件改变后发生的这种深层流体中的沉淀物能够在Ba/Sr-硫酸盐相中积聚镭同位素。226Ra之间的放射性不平衡的时间依赖性,228Ra及其子228Th在这种尺度上由数学模型描述,并应用于两种不同的摄取模型。基于这种方法,对地热工厂不同组件中发现的沉淀物进行了年龄测定。它们揭示了由于植物中的修饰而引起的水垢形成的触发。结果适合得出有关系统运行的结论,这导致规模的减少和停机时间的减少。
    The occurrence of enhanced concentration of the radium triplet 226Ra, 228Ra and 224Ra is a frequently observed property of highly saline anoxic deep water as used e.g. in geothermal plants. In the present study we develop a model to explain the observed activity levels in the brines. The model considers processes at the rock-fluid interface of the aquifer like alpha recoil, sorption and surface precipitation and is implemented by means of a Monte Carlo simulation. The outcomes of the simulations indicate the dominating role of fine-grained constituents of the reservoir rock, e.g. claystone with enhanced specific activities of the natural decay chains. Mass fractions of such material in the order of a few percent are sufficient to result in radium fluid concentrations >1 Bq l-1. Also a generally valid relation between the Th/U ratio in the aquifer rock and the 228Ra/226Ra activity ratio in the fluid was found. This link improves the agreement between radium fluid data and the mean Th/U ratio of the Earth\'s crust. The 224Ra/228Ra fluid ratios reflect the transport time from the location of last radium release to the sampling point. The model findings were applied to a well investigated aquifer used in a geothermal plant in the North German Basin. An eight component system of the aquifer rock was established as the basis for the simulation of the radium concentrations in the deep fluid. The comparison between simulation and fluid analyses revealed a degree of radium sorption of about 50 %, which is necessary to match the model\'s results with the measurements. On the other hand, the 228Ra/226Ra fluid ratio of the brine was well reproduced by the simulation, showing the suitability of the model even in complex heterogeneous reservoirs. From the 224Ra/228Ra fluid ratios a transition from pore-to fracture-guided transport < 10 m distance from the production well is suggested. Precipitates from such deep fluids occurring after changes of the thermodynamic conditions are able to accumulate radium isotopes in Ba/Sr-sulphate phases. The time dependence of the radioactive disequilibrium between 226Ra, 228Ra and its child 228Th in such scales is described by a mathematical model and is applied to two different uptake models. Based on this approach, age determinations on precipitates found in different components of a geothermal plant are conducted. They reveal the triggering of scale formation due to modifications in the plant. The results are suitable for drawing conclusions about the operation of the system, which result in a reduction in the amount of scale and a reduction in downtimes.
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    文章类型: Journal Article
    体育活动的年龄估计,法定年龄的确定和移民目的往往是必不可少的,这使得需要科学证明的年龄估计方法的医疗实践的一个重要方面。法医牙本质学是法医实践的重要方面,可能是年龄估计的名副其实的工具。
    这项研究的目的是评估正像图(OPG)在选定的尼日利亚人年龄估计中的有用性。
    根据Olze等人(2010)描述的方法,对202个OPG进行了回顾性评估,以回顾第三磨牙牙周膜的可见性,并完成了牙根形成。然后通过从以年份记录的出生日期中扣除暴露日期来计算个人年龄。计算每组的平均年龄和标准偏差。
    评估在OPGs上看到的牙周膜的射线照相可见性的每个阶段的最小和最大年龄,表明该阶段增加的年龄逐渐增加,除了少数例外。牙周膜的射线照相可见性比较显示,与女性相比,男性倾向于达到早期牙周可见性阶段,但在后期观察到相反的情况。在第1至第3阶段中发现的任何人都可能达到17岁,因为在这些阶段中发现的最低年龄超过17岁。
    除了少数例外,在OPG上评估牙周膜的可见性可以充分预测个体的年龄。因此,在法医年龄估计的情况下,这种方法的使用可能需要与其他方法相结合,以准确确定牙齿年龄。
    UNASSIGNED: Age estimation for sporting activities, legal age determination and migration purpose is oftentimes essential, which makes the need for a scientifically proven method of age estimation an important aspect of medical practice. Forensic odontology is an essential aspect of forensic practice and may be a veritable tool in age estimation.
    UNASSIGNED: The objective of this study was to evaluate the usefulness of orthopantomograms (OPG) in age estimation among selected Nigerians.
    UNASSIGNED: A retrospective assessment of 202 OPGs was done to review the visibility of the periodontal ligament of third molars with completed root formation according to the methods described by Olze et al (2010). Individual ages were then calculated by deducting date of exposure from the date of birth recorded in years. Mean age with standard deviation were calculated for each group.
    UNASSIGNED: Assessing the minimum and maximum age at which each of the stages of the radiographic visibility of the periodontal ligament as seen on the OPGs revealed that there was a gradual increase in the age at which the stage increment occurred, with a few exceptions. Comparison of the radiographic visibility of the periodontal ligament revealed that males tend to achieve early periodontal visibility stages compared to females, but the reverse was observed in later stages. Age 17 is more than likely attained in any person found within stages 1 to 3 as the minimum age found in these stages were above 17 years.
    UNASSIGNED: With a few exceptions, the assessment of periodontal ligament visibility on OPGs can adequately predict the age of individuals. Thus, the use of this method may need to be combined with other methods in accurate determination of dental age in instances of forensic age estimation.
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  • 文章类型: Journal Article
    目标:年龄估计在个人身份识别中起着至关重要的作用,特别是在确定青少年同意年龄时。同意年龄是指个人在法律上被认为能够为性活动提供知情同意的最低年龄。这项研究的目的是通过使用牙齿发育与机器学习相结合来确定青少年是否满足14或18岁。
    方法:这项研究结合了牙科评估和机器学习技术,以预测青少年是否已达到14或18岁的同意年龄。如第三磨牙的分期等因素,第三摩尔指数,并评价第二磨牙牙周膜的可见性。
    结果:性能指标的差异表明,机器学习获得的后验概率在14岁时超过93%,在18岁时略低。
    结论:这项研究为青少年个人鉴定法医鉴定提供了有价值的见解,强调通过将传统方法与机器学习相结合来提高该人群年龄确定准确性的潜力。它强调了保护和尊重所有有关个人尊严的重要性。
    OBJECTIVE: Age estimation plays a critical role in personal identification, especially when determining compliance with the age of consent for adolescents. The age of consent refers to the minimum age at which an individual is legally considered capable of providing informed consent for sexual activities. The purpose of this study is to determine whether adolescents meet the age of 14 or 18 by using dental development combined with machine learning.
    METHODS: This study combines dental assessment and machine learning techniques to predict whether adolescents have reached the consent age of 14 or 18. Factors such as the staging of the third molar, the third molar index, and the visibility of the periodontal ligament of the second molar are evaluated.
    RESULTS: Differences in performance metrics indicate that the posterior probabilities achieved by machine learning exceed 93% for the age of 14 and slightly lower for the age of 18.
    CONCLUSIONS: This study provides valuable insights for forensic identification for adolescents in personal identification, emphasizing the potential to improve the accuracy of age determination within this population by combining traditional methods with machine learning. It underscores the importance of protecting and respecting the dignity of all individuals involved.
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  • 文章类型: Journal Article
    进行这项回顾性研究是为了评估儿童牙齿年龄估计的不同方法,并检查使用锥形束计算机断层扫描(CBCT)数据进行年龄估计的可行性。共从100名9至16岁的儿童中获取了200份射线照相记录(包括数字全景射线照相和CBCT),都是在相同的日期拍摄的。射线照相数据是从存档记录中获取的,包括全景射线照相和属于同一个人的CBCT数据。当全景射线照相数据不足时,使用CBCT。使用MIMICS软件从CBCT数据计算下颌骨中左第一磨牙的牙髓体积和牙髓/牙齿体积比。此外,年龄是通过Demirjian和Willems方法从全景射线照相图像获得的数据中估算的。必要时进行统计分析和线性回归分析。Demirjian法的均数差异与实际年龄有统计学意义,以及Willims方法和实际年龄之间(p<0.001)。在从牙髓体积(R2=0.098)和牙髓/牙齿体积比(R2=0.395)数据创建的线性回归模型中,对于估计的牙齿年龄分析(p<0.001)实现统计学上的显著性,并且观察到与实际年龄的负相关。当将CBCT数据的估计牙齿年龄与实际年龄进行比较时,与仅使用牙髓体积数据相比,牙髓/牙齿体积比方法得出的结果更接近实际年龄。当同时考虑全景射线照相年龄估计方法和使用CBCT数据的年龄估计方法时,我们发现用Willems方法获得的结果,全景射线照相年龄估计技术,提供了与实际年龄最接近的结果。关于使用牙髓和牙齿体积作为替代方法进行年龄估计的可行性,应该对文献做出更多贡献。
    This retrospective study was conducted to evaluate different methods for dental age estimation in children and to examine the feasibility of using cone beam computed tomography (CBCT) data for age estimation. A total of 200 radiographic records (both digital panoramic radiographs and CBCTs) were acquired from 100 children aged 9 to 16 years, all taken on the same dates. Radiographic data was acquired from archived records and included both panoramic radiography and CBCT data belonging to the same individual. CBCT was used when panoramic radiographic data was insufficient. The pulp volume and pulp/tooth volume ratio of the left first molar teeth in the mandible were calculated from the CBCT data using MIMICS software. In addition, age was estimated by the Demirjian and Willems methods from data obtained from panoramic radiography images. Statistical analyses and linear regression analysis were performed as necessary. There was a statistically significant difference between the mean difference between the Demirjian method and chronological age, and between the Willems method and chronological age (p < 0.001). Statistically significance was achieved in a linear regression model created from pulp volume (R2 = 0.098) and pulp/tooth volume ratio (R2 = 0.395) data for the estimated dental age analysis (p < 0.001) and a negative correlation was observed with chronological age. When compared estimated dental age from CBCT data with chronological age, the pulp/tooth volume ratio method yielded results closer to chronological age than using only pulp volume data. When considering both panoramic radiographic age estimation methods and age estimation methods using CBCT data, we found that the results obtained with the Willems method, a panoramic radiographic age estimation technique, provided the closest results to the chronological age. More contributions should be made to the literature regarding the feasibility of age estimation using pulp and tooth volume as an alternative method.
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  • 文章类型: Journal Article
    本系统综述的目的是分析文献,以确定人工智能方法是否有效地确定全景射线照片中的年龄。在PubMed/Medline中进行了无语言和年份限制的搜索,Embase,WebofScience,和Scopus数据库。还进行了手工搜索,并在专门期刊上搜索未发表的手稿。36篇文章被纳入分析。人工方法和人工智能技术在均方根误差和平均绝对误差方面存在显著差异,有利于使用人工智能(p<0.00001)。很少有文章将深度学习方法与机器学习模型或手动模型进行比较。尽管机器学习在数据处理和深度学习在数据收集和分析方面具有优势,无可比性数据是本研究的局限性.需要更多的信息来比较这些技术,特别强调时间作为一个变量。
    The aim of this systematic review is to analyze the literature to determine whether the methods of artificial intelligence are effective in determining age in panoramic radiographs. Searches without language and year limits were conducted in PubMed/Medline, Embase, Web of Science, and Scopus databases. Hand searches were also performed, and unpublished manuscripts were searched in specialized journals. Thirty-six articles were included in the analysis. Significant differences in terms of root mean square error and mean absolute error were found between manual methods and artificial intelligence techniques, favoring the use of artificial intelligence (p < 0.00001). Few articles compared deep learning methods with machine learning models or manual models. Although there are advantages of machine learning in data processing and deep learning in data collection and analysis, non-comparable data was a limitation of this study. More information is needed on the comparison of these techniques, with particular emphasis on time as a variable.
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  • 文章类型: Journal Article
    目的:我们旨在从1日开始建立结合MRI体积测量的模型,第2磨牙和第3磨牙用于亚成人的年龄预测,并比较所有三个磨牙的不同组合的年龄预测性能,在研究队列的内部。
    方法:我们使用具有定制高分辨率单T2序列的1.5TMR扫描仪检查了99名志愿者。使用SliceOmatic(Tomovision©)进行分割。年龄预测基于牙齿组织比率(高信号软组织+低信号软组织)/总数。该模型包括三个相关参数,以说明磨牙之间的统计依赖性。使用四分位距(IQR)评估了三个磨牙的不同牙齿组合的年龄预测性能。
    结果:我们包括来自87名参与者的第一磨牙的数据(F/M59/28),第二磨牙93(F/M60/33)和第三磨牙67(F/M45/22)。年龄范围为14-24岁,中位年龄为18岁。具有最佳年龄预测性能(最小IQR)的模型在男性中为46-47-18(右下第一和第二和右上第三磨牙)。不同磨牙之间的估计相关性为0.620(46与47),0.430(46vs.18),和0.598(47vs.18).IQR在包括第三磨牙的牙齿组合中是最小的。
    结论:我们已经建立了一个模型,用于从1日开始组合组织体积测量值,第2磨牙和第3磨牙用于亚成人年龄预测。预测性能主要由第三磨牙驱动。涉及第三摩尔的所有组合表现良好。
    OBJECTIVE: We aimed to establish a model combining MRI volume measurements from the 1st, 2nd and 3rd molars for age prediction in sub-adults and compare the age prediction performance of different combinations of all three molars, internally in the study cohort.
    METHODS: We examined 99 volunteers using a 1.5 T MR scanner with a customized high-resolution single T2 sequence. Segmentation was performed using SliceOmatic (Tomovision©). Age prediction was based on the tooth tissue ratio (high signal soft tissue + low signal soft tissue)/total. The model included three correlation parameters to account for statistical dependence between the molars. Age prediction performance of different combinations of teeth for the three molars was assessed using interquartile range (IQR).
    RESULTS: We included data from the 1st molars from 87 participants (F/M 59/28), 2nd molars from 93 (F/M 60/33) and 3rd molars from 67 (F/M 45/22). The age range was 14-24 years with a median age of 18 years. The model with the best age prediction performance (smallest IQR) was 46-47-18 (lower right 1st and 2nd and upper right 3rd molar) in males. The estimated correlation between the different molars was 0.620 (46 vs. 47), 0.430 (46 vs. 18), and 0.598 (47 vs. 18). IQR was the smallest in tooth combinations including a 3rd molar.
    CONCLUSIONS: We have established a model for combining tissue volume measurements from the 1st, 2nd and 3rd molars for age prediction in sub-adults. The prediction performance was mostly driven by the 3rd molars. All combinations involving the 3rd molar performed well.
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  • 文章类型: Journal Article
    背景:准确的年龄估计对于临床和法医学目的至关重要。随着人工智能(AI)技术的快速发展,依靠牙齿发育的传统方法,虽然可靠,可以通过利用深度学习来增强,特别是神经网络。这项研究通过将整个全景图像用于年龄估计来评估AI模型的效率。通过监督学习(SL)模型分析结果表现。
    方法:将27,877张5至90岁的牙科全景图像按2种类型进行分类。在类型1中,它们按每个年龄分类,在类型2中,应用启发式分组,20岁以上的年龄每5年分类一次.宽ResNet(WRN)和DenseNet(DN)用于监督学习。此外,在这两种类型中进行了±3年偏差的分析.
    结果:对于DN模型,1型分组的准确率为0.1016,F1评分为0.058,2型分组的准确率为0.3146,F1评分为0.2027.结合±3年的偏差,1型和2型的准确性分别为0.281、0.7323;F1评分分别为0.1768、0.6583。对于WRN模型,1型分组的准确率为0.1041,F1评分为0.0599,2型分组的准确率为0.3182,F1评分为0.2071.结合±3年的偏差,1型和2型的准确性分别为0.2716,0.7323;F1评分分别为0.1709,0.6437。
    结论:将整个全景图像数据用于通过启发式分类进行监督分类,对监督学习模型进行±3年的偏差分组,并证明了年龄估计的令人满意的结果。
    Accurate age estimation is vital for clinical and forensic purposes. With the rapid advancement of artificial intelligence(AI) technologies, traditional methods relying on tooth development, while reliable, can be enhanced by leveraging deep learning, particularly neural networks. This study evaluated the efficiency of an AI model by applying the entire panoramic image for age estimation. The outcome performances were analyzed through supervised learning (SL) models.
    Total of 27,877 dental panorama images from 5 to 90 years of age were classified by 2 types of grouping. In type 1 they were classified by each age and in type 2, applying heuristic grouping, the age over 20 years were classified by every 5 years. Wide ResNet (WRN) and DenseNet (DN) were used for supervised learning. In addition, the analysis with ± 3 years of deviation in both types were performed.
    For the DN model, while the type 1 grouping achieved an accuracy of 0.1016 and F1 score of 0.058, the type 2 achieved an accuracy of 0.3146 and F1 score of 0.2027. Incorporating ± 3years of deviation, the accuracy of type 1 and 2 were 0.281, 0.7323 respectively; and the F1 score were 0.1768, 0.6583 respectively. For the WRN model, while the type 1 grouping achieved an accuracy of 0.1041 and F1 score of 0.0599, the type 2 achieved an accuracy of 0.3182 and F1 score of 0.2071. Incorporating ± 3years of deviation, the accuracy of type 1 and 2 were 0.2716, 0.7323 respectively; and the F1 score were 0.1709, 0.6437 respectively.
    The application of entire panorama image data for supervised with classification by heuristics grouping with ± 3years of deviation for supervised learning models and demonstrated satisfactory outcome for the age estimation.
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  • 文章类型: Meta-Analysis
    端粒是覆盖染色体末端的短重复DNA序列。端粒缩短发生在细胞分裂过程中,可通过氧化损伤加速或通过端粒维持机制改善。因此,端粒长度随年龄变化,最近在一项跨脊椎动物的大型荟萃分析中证实了这一点。然而,基于端粒长度和年龄之间的相关性,结论是端粒长度可以用作动物按实际年龄估计的工具。相关性不应与可预测性混淆,目前的数据和研究表明,端粒不能用于可靠地预测个体的实际年龄。端粒动力学存在较大个体差异的生物学原因,这主要是由于对各种环境的高度敏感性,还有遗传因素,将端粒作为年龄估计的工具不可行。使用端粒进行实际年龄估计在很大程度上是一种误导的努力,但它偶尔出现在文献中,引起了人们的担忧,即它会误导野生动物保护资源。
    Telomeres are short repetitive DNA sequences capping the ends of chromosomes. Telomere shortening occurs during cell division and may be accelerated by oxidative damage or ameliorated by telomere maintenance mechanisms. Consequently, telomere length changes with age, which was recently confirmed in a large meta-analysis across vertebrates. However, based on the correlation between telomere length and age, it was concluded that telomere length can be used as a tool for chronological age estimation in animals. Correlation should not be confused with predictability, and the current data and studies suggest that telomeres cannot be used to reliably predict individual chronological age. There are biological reasons for why there is large individual variation in telomere dynamics, which is mainly due to high susceptibility to a wide range of environmental, but also genetic factors, rendering telomeres unfeasible as a tool for age estimation. The use of telomeres for chronological age estimation is largely a misguided effort, but its occasional reappearance in the literature raises concerns that it will mislead resources in wildlife conservation.
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  • 文章类型: Journal Article
    美国埋葬甲虫,美洲显微镜Olivier,是一种联邦保护的昆虫,曾经占据了北美东部的大部分地区。成年甲虫的特征明显,在前胸和垂直线上可识别的标记,并观察到颜色随年龄的变化。研究科学家和保护从业人员面临的挑战之一是在包括teneral(年轻)和衰老(老年)成年阶段之间确定甲虫年龄的能力。使用20只(10只雄性和10只雌性)圈养甲虫,我们描述了灰度和红色的变化,绿色,和蓝色(RGB)颜色通道在每个甲虫的寿命,用于现场老化应用。从羽化到死亡,以固定的间隔拍摄个体甲虫,使用开源ImageJ版本1.54f软件提取颜色数据。一系列线性混合效应模型确定,在前胸和囊纹的所有颜色通道中,红色显示出最急剧下降。前胸的减少更明显。前胸和外衣标记之间的灰度变化明显不同,前胸底部变黑更快。在俄克拉荷马州的野外条件下测试了所得的前胸膜颜色图,299岁的成年美国人,和六个年龄类别(日范围)可以通过眼睛辨别:teneral(0-15),晚音(15-31),早熟(31-45),成熟(45-59),早期衰老(59-76),和衰老(76-90)。更精确估计年龄的能力将改善人口结构估计,实验室育种计划,以及潜在的重新引入努力。
    The American burying beetle, Nicrophorus americanus Olivier, is a federally protected insect that once occupied most of eastern North America. Adult beetles feature distinct, recognizable markings on the pronotum and elytra, and color changes with age have been observed. Among the challenges faced by research scientists and conservation practitioners is the ability to determine beetle age in the field between and including teneral (young) and senescent (old) adult stages. Using 20 (10 male and 10 female) captive-bred beetles, we characterized the change in greyscale and red, green, and blue (RGB) color channels over the lifespan of each beetle for field-aging applications. Individual beetles were photographed at set intervals from eclosion to death, and color data were extracted using open-source ImageJ Version 1.54f software. A series of linear mixed-effects models determined that red color showed the steepest decrease among all color channels in the pronotum and elytral markings, with a more significant decrease in the pronotum. The change in greyscale between the pronotum and elytral markings was visibly different, with more rapid darkening in the pronotum. The resulting pronotum color chart was tested under field conditions in Oklahoma, aging 299 adult N. americanus, and six age categories (day range) were discernable by eye: teneral (0-15), late teneral (15-31), early mature (31-45), mature (45-59), early senescent (59-76), and senescent (76-90). The ability to more precisely estimate age will improve population structure estimates, laboratory breeding programs, and potential reintroduction efforts.
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