■接受经皮PFO封堵术的卵圆孔未闭(PFO)患者与接受药物治疗的PFO患者相比,发生房颤(AF)的风险更大。如果接受治疗,封堵后房颤似乎具有良好的耐受性,但可能会增加中风的风险。据报道,封堵后房颤发生在3.7%至7.4%的患者中;然而,跨设备的发病率仍然不确定。本研究旨在评估封堵后房颤的频率,房扑,和6个PFO封堵器中的心律失常。
■2001年至2021年期间,有44例患者接受了经皮PFO封堵术,并进行了适当的随访。该程序使用雅培AmplatzerPFO进行,AmplatzerASD,AmplatzerCribriform,NMT心脏密封,GoreHelex,或Gore心形装置.房颤发生率,房扑,在关闭后6个月内通过心电图评估心律失常。多变量逻辑回归评估了封堵后房颤或房扑的潜在预测因素。
■封堵后房颤或房扑在30例(6.7%)6个月内发生,其发病率在不同设备之间有显著差异。与其他装置相比,Gore心脏型封堵后房颤或房扑事件的发生频率最高(16.8%)。Gore心形装置,更大的设备尺寸,男性和男性与封堵后房颤或房扑的风险增加相关。
■在Gore心脏造形装置中更可能发生封堵后房颤或房扑,在男性中,以及使用较大装置进行PFO闭合的患者。虽然它对于完全关闭更有效,研究表明,Gore心形装置是封堵后房颤或房扑的独立预测因子.
UNASSIGNED: Patients with a patent foramen ovale (PFO) who undergo percutaneous PFO closure are at a greater risk of developing atrial fibrillation (AF) compared with patients whose PFOs are managed medically. Postclosure AF appears to be well tolerated if treated but may increase the risk for stroke. Postclosure AF is reported to occur in 3.7% to 7.4% of patients; however, incidence across devices remains uncertain. This study aims to evaluate the frequency of postclosure AF, atrial flutter, and arrhythmias in 6 PFO closure devices.
UNASSIGNED: Four hundred forty-five patients underwent percutaneous PFO closure with appropriate follow-up between 2001 and 2021. The procedure was performed using Abbott Amplatzer PFO, Amplatzer ASD, Amplatzer Cribriform, NMT CardioSEAL, Gore Helex, or Gore Cardioform devices. Incidence of AF, atrial flutter, and arrhythmias were assessed by electrocardiogram within 6 months from closure. Multivariate logistic regression evaluated potential predictors of postclosure AF or atrial flutter.
UNASSIGNED: Postclosure AF or atrial flutter occurred in 30 patients (6.7%) within 6 months, and its incidence was significantly different across devices. Gore Cardioform had the greatest frequency of postclosure AF or atrial flutter events (16.8%) compared with other devices. The Gore Cardioform device, larger device sizes, and male sex were associated with greater risk of postclosure AF or atrial flutter.
UNASSIGNED: Postclosure AF or atrial flutter was more likely to occur in the Gore Cardioform device, in males, and in patients who underwent PFO closure with larger devices. Although it is more effective for complete closure, the Gore Cardioform device was shown to be an independent predictor of postclosure AF or atrial flutter.