目的:评估终止妊娠(TOP)后胎儿异常的整个后续妊娠的情绪困扰和产前依恋。
方法:观察性研究,在法国的第三级产妇。
方法:25名妇女因胎儿异常而终止妊娠,18岁及以上。20个妊娠周(GW)的产前访谈,27GW和35GW以及产后3个月和每次自我管理的焦虑问卷,创伤后应激综合征(PCLS)抑郁症状(EPDS),产前依恋(PAI)和围产期悲伤量表(PGS)。
结果:怀孕开始,即在20GW之前,焦虑患病率增加(16/23,66.7%),抑郁(7/23,30.4%)和创伤后应激症状(4/16,25%)。妊娠开始时PGS的总分高于妊娠晚期(p=0.005)。妊娠早期产前依恋较低(p=0.003),与悲伤强度成反比(p=0.022)。在怀孕后期,情绪症状减少,产前依恋停止积极增加,特别是在先前怀孕中胎儿异常被诊断为晚期的女性中,平均为25GW。
结论:这项研究显示了TOP后妊娠的具体动态,并强调了早期产前心理支持的必要性。即使在知道胎儿健康之后,也应特别注意妊娠晚期的产前依恋。
OBJECTIVE: To evaluate emotional distress and prenatal attachment throughout a subsequent pregnancy after Termination of Pregnancy (TOP) for fetal abnormality.
METHODS: Observational study, in a French Tertiary Maternity.
METHODS: 25 women in a subsequent pregnancy after a medical termination of pregnancy for foetal abnormality, 18-year-old and older. Prenatal Interviews at 20 Gestationnal weeks (GW), 27 GW and 35 GW and Postnatal at 3 months and at each time self-administered questionnaires of anxiety, post-traumatic stress syndrome (PCLS) depressive symptoms (EPDS), prenatal attachment (PAI) and Perinatal Grief Scale (PGS).
RESULTS: Pregnancy onset, i.e. before 20 GW, showed increased prevalence of anxiety (16/23, 66.7%), depression (7/23, 30.4%) and post-traumatic stress symptoms (4/16, 25%). Total score on PGS is higher in onset of pregnancy than in the third trimester (p = 0.005). Prenatal attachment was lower during early pregnancy (p = 0.003) and correlated inversely with grief intensity (p = 0.022). During late pregnancy, emotional symptoms decrease, and prenatal attachment stopped increase positively, specifically among women whose foetal abnormality in previous pregnancies were diagnosed late, at an average of 25 GW.
CONCLUSIONS: This research shows the specific dynamics of pregnancies following TOP and highlights the necessity for early prenatal psychological support. One should also pay special attention to prenatal attachment during late pregnancy even after knowing that the fetus is healthy.