recognition

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  • 文章类型: Journal Article
    在学术职业中,出版物对于高风险的就业决策至关重要,认可,和晋升。因此,需要公正的框架来评估学术医师书目的严谨性。本文提供了根据作者立场评估参考书目的客观标准,出版物类型,影响,volume,专题重点,和轨迹。对医师参考书目公平评估的主要威胁包括代表性不足和专业机会方面的差异,不承认弱势作者的成功,利用出版物获得青睐和滥用权力地位。评估书目的无偏见标准减轻了这些对公平评估的威胁。
    In the academic professions, publications are essential for high-stakes decisions about employment, recognition, and promotion. Therefore, impartial frameworks are needed for evaluating the rigor of scholarly physicians\' bibliographies. This article provides objective criteria for evaluating bibliographies based on author position, publication type, impact, volume, thematic focus, and trajectory. Key threats to the fair assessment of physicians\' bibliographies include disparities regarding underrepresentation and professional opportunities, not recognizing the successes of disadvantaged authors, and exploiting publications to gain favor and abuse positions of power. Unbiased criteria for evaluating bibliographies mitigate these threats to fair assessment.
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  • 文章类型: Journal Article
    疼痛会自动干扰正在进行的认知过程,例如注意力和记忆力。疼痛对认知功能的负面影响程度似乎取决于自上而下和自下而上因素之间的平衡。
    在这个大的,预注册,对8项研究进行汇总再分析,我们调查了急性疼痛对识别记忆的有害影响的鲁棒性,以及自上而下的机制,如疼痛相关的期望或认知(疼痛相关的恐惧,疼痛灾难化)调节这种效果。
    二百四十七个健康参与者经历了类似的实验范式,包括视觉分类任务,其中图像随机配对(或没有)伴随的疼痛刺激以及随后的未通知识别任务。识别记忆(即,d\',回忆,和熟悉度)和分类性能(即,反应时间,准确性)作为疼痛对认知能力影响的代理。
    急性疼痛刺激显着损害识别性能(d\',熟悉度)。然而,在该健康参与者样本中,参与者对疼痛对任务表现或疼痛相关认知的影响的预期并未显著调节识别表现.
    我们的研究结果证实了以前的研究和慢性疼痛患者的“记忆问题”报告中报道的疼痛对(视觉)记忆编码的负面影响。描述自下而上和自上而下因素对疼痛有害影响的作用,大规模的研究与更细致的研究设计是必要的。患者队列的未来研究必须揭示慢性疼痛患者的适应不良疼痛相关认知和经常报告的认知功能受损之间的相互作用。
    UNASSIGNED: Pain can automatically interfere with ongoing cognitive processes such as attention and memory. The extent of pain\'s negative effects on cognitive functioning seems to depend on a balance between top-down and bottom-up factors.
    UNASSIGNED: In this large, preregistered, pooled reanalysis of 8 studies, we investigated the robustness of the detrimental effect of acute pain on recognition memory and whether top-down mechanisms such as pain-related expectations or cognitions (pain-related fear, pain catastrophizing) modulate this effect.
    UNASSIGNED: Two hundred forty-seven healthy participants underwent similar experimental paradigms, including a visual categorization task with images randomly paired with (or without) concomitant painful stimulation and a subsequent unannounced recognition task. Recognition memory (ie, d\', recollection, and familiarity) and categorization performance (ie, reaction time, accuracy) served as proxies for the effect of pain on cognitive performance.
    UNASSIGNED: Acute painful stimulation significantly impaired recognition performance (d\', familiarity). However, recognition performance was not significantly modulated by participants\' expectations regarding the effect of pain on task performance or pain-related cognitions in this sample of healthy participants.
    UNASSIGNED: Our results corroborate the negative effects of pain on (visual) memory encoding reported in previous studies and reports of \"memory problems\" from patients with chronic pain. To characterize the role of bottom-up and top-down factors for the detrimental effects of pain, large-scale studies with more nuanced study designs are necessary. Future studies in patient cohorts must unravel the interaction of maladaptive pain-related cognitions and the often-reported impaired cognitive performance in chronic pain patients.
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  • 文章类型: Journal Article
    我们开发了一个手术支持系统,该系统使用人工智能(AI)可视化重要的显微解剖结构。这项研究评估了其在肺癌手术中识别胸神经的准确性。识别模型是通过深度学习使用为神经精确注释的图像创建的。使用Dice指数和Jaccard指数进行计算评估。四名普通胸外科医师评估了神经识别的准确性。Further,时滞的差异,评估AI系统和手术监护仪之间的图像质量和运动平滑度.使用五点标度进行评级。计算评估相对较好,骰子指数为0.56,雅卡德指数为0.39。AI系统用于10例肺癌胸腔镜手术。胸神经识别的准确性令人满意,召回评分为4.5±0.4,精确度评分为4.0±0.9。虽然运动平稳性(3.2±0.4)略有差异,AI系统和手术监护仪之间的时间滞后(4.9±0.3)和图像质量(4.6±0.5)几乎没有差异。总之,AI手术支持系统在识别胸神经方面具有令人满意的准确性。
    We developed a surgical support system that visualises important microanatomies using artificial intelligence (AI). This study evaluated its accuracy in recognising the thoracic nerves during lung cancer surgery. Recognition models were created with deep learning using images precisely annotated for nerves. Computational evaluation was performed using the Dice index and the Jaccard index. Four general thoracic surgeons evaluated the accuracy of nerve recognition. Further, the differences in time lag, image quality and smoothness of movement between the AI system and surgical monitor were assessed. Ratings were made using a five-point scale. The computational evaluation was relatively favourable, with a Dice index of 0.56 and a Jaccard index of 0.39. The AI system was used for 10 thoracoscopic surgeries for lung cancer. The accuracy of thoracic nerve recognition was satisfactory, with a recall score of 4.5 ± 0.4 and a precision score of 4.0 ± 0.9. Though smoothness of motion (3.2 ± 0.4) differed slightly, nearly no difference in time lag (4.9 ± 0.3) and image quality (4.6 ± 0.5) between the AI system and the surgical monitor were observed. In conclusion, the AI surgical support system has a satisfactory accuracy in recognising the thoracic nerves.
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  • 文章类型: Journal Article
    社交动物需要跟踪他们群体中的其他个体,以便能够相应地调整他们的行为并促进群体凝聚力。这种识别能力因物种而异,并受到学习和记忆等认知能力的影响。在爬行动物中,尤其是Squamates(蜥蜴,蛇,和蠕虫蜥蜴),化学通信是地域性的关键,繁殖,和其他社会互动。然而,这些社会互动背后的认知过程仍未得到充分研究。在我们的研究中,我们研究了雄性和雌性Tokay壁虎(Gekkogecko)在化学上区分熟悉和不熟悉的交配伴侣的能力。我们的研究结果表明,两性都可以做出这种区分,雄性对熟悉伴侣的气味有更多的反应,女性对陌生伴侣的反应更多。蜥蜴在分离后保持了两到三周的歧视能力,但最多不到六周。这项研究强调了使用气味作为社会刺激来调查蜥蜴的社会认知的功效,一个有希望的途径来更好地了解这些动物的社会认知。
    Social animals need to keep track of other individuals in their group to be able to adjust their behaviour accordingly and facilitate group cohesion. This recognition ability varies across species and is influenced by cognitive capacities such as learning and memory. In reptiles, particularly Squamates (lizards, snakes, and worm lizards), chemical communication is pivotal for territoriality, reproduction, and other social interactions. However, the cognitive processes underlying these social interactions remain understudied. In our study, we examined the ability of male and female Tokay geckos (Gekko gecko) to chemically differentiate familiar and unfamiliar mating partners. Our findings suggest that both sexes can make this distinction, with males responding more to the odour of a familiar mate, and females responding more to unfamiliar mates. The lizards maintained their discriminatory abilities for two to three weeks but not up to six weeks after separation. This research highlights the efficacy of using odours as social stimuli for investigating social cognition in lizards, a promising avenue to better understand social cognition in these animals.
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  • 文章类型: Journal Article
    动机和情绪对记忆的影响已被广泛研究;然而,尽管这些结构之间有联系,它们已经在不同的研究领域进行了研究,很少有工作同时检查它们的效果。当前的研究采用了一种新颖的方法来正交地操纵动机和情绪影响,在同样的任务中,来测试它们在有意记忆形成上的相互作用。如果情感和奖励动机紧密相连,它们可能依赖于重叠的认知机制,因此,我们不会期望情感和奖励在记忆中相互作用。或者,它们可能是不同的结构,因此当两者都包含在同一个实验试验中时,会增强记忆,超越加性效应。为了测试这些相互竞争的预测,在实验1中,参与者(n=180)以情绪(消极,积极)和中性词故意编码高或低奖励预期线索。在实验2中,参与者(n=159)用高或低的奖励提示编码情感和中性词,但是记忆是使用研究测试块免费回忆测试的。两个实验的结果都是一致的。情绪和奖励在一般假设的方向上有主要影响,但没有证据表明这些因素之间存在相互作用。这与情感和奖励动机是相似结构的预测是一致的。在试验中,它们的组合并不能单独增强这些因素中的任何一个,这可能表明这些结构具有相似的认知机制。
    Motivational and emotional influences on memory have been studied extensively; however, despite the link between these constructs, they have been studied in separate lines of research, with very little work examining their effects concurrently. The current study takes a novel approach to manipulate motivational and emotional influences orthogonally, and within the same task, to test their interplay on intentional memory formation. If emotion and reward motivation are tightly linked, they may rely on overlapping cognitive mechanisms, thus we would not expect emotion and reward to interact in memory. Alternatively, they could be distinct constructs and therefore would boost memory when both are included in the same experimental trial, above and beyond additive effects. To test these competing predictions, in Experiment 1, participants (n = 180) completed an old/new recognition memory task with emotional (negative, positive) and neutral words intentionally encoded with high or low reward anticipation cues. In Experiment 2, participants (n = 159) encoded emotional and neutral words with a high or low reward cue, but memory was tested with free recall using study-test blocks. The findings from both experiments converged. There were main effects of emotion and reward in generally hypothesized directions, but no evidence of an interaction between these factors. This is in line with the prediction that emotion and reward motivation are similar constructs. Their combination within a trial does not boost memory above and beyond either of these factors alone perhaps indicating these constructs have similar cognitive mechanisms.
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  • 文章类型: Journal Article
    心血管疾病仍然是人类健康的主要威胁之一,显著影响质量和预期寿命。有效和迅速地识别这些疾病至关重要。这项研究旨在开发一种有效的新型混合方法,用于根据心脏病患者的短心电图(ECG)片段自动检测危险的心律失常。这项研究建议使用连续小波变换(CWT)将ECG信号转换为图像(扫描图),并检查将短的2s段ECG信号分为四组可电击的危险心律失常的任务,包括室性扑动(C1),心室纤颤(C2),室性心动过速尖端扭转(C3),和高速率室性心动过速(C4)。我们建议开发一种具有深度学习架构的新型混合神经网络来对危险的心律失常进行分类。这项工作利用从PhysioNet数据库获得的实际心电图(ECG)数据,与由合成少数过采样技术(SMOTE)方法产生的人工生成的ECG数据一起,解决类分布不平衡的问题,以获得精度训练模型。实验结果表明,该方法具有较高的精度,灵敏度,特异性,精度,F1得分为97.75%,97.75%,99.25%,97.75%,和97.75%,分别,在对所有四类可电击心律失常进行分类方面,优于传统方法。我们的工作在现实生活中具有重要的临床价值,因为它有可能显着提高心脏病患者危及生命的心律失常的诊断和治疗。此外,我们的模型还展示了对其他两个数据集的适应性和通用性。
    Cardiovascular diseases remain one of the main threats to human health, significantly affecting the quality and life expectancy. Effective and prompt recognition of these diseases is crucial. This research aims to develop an effective novel hybrid method for automatically detecting dangerous arrhythmias based on cardiac patients\' short electrocardiogram (ECG) fragments. This study suggests using a continuous wavelet transform (CWT) to convert ECG signals into images (scalograms) and examining the task of categorizing short 2-s segments of ECG signals into four groups of dangerous arrhythmias that are shockable, including ventricular flutter (C1), ventricular fibrillation (C2), ventricular tachycardia torsade de pointes (C3), and high-rate ventricular tachycardia (C4). We propose developing a novel hybrid neural network with a deep learning architecture to classify dangerous arrhythmias. This work utilizes actual electrocardiogram (ECG) data obtained from the PhysioNet database, alongside artificially generated ECG data produced by the Synthetic Minority Over-sampling Technique (SMOTE) approach, to address the issue of imbalanced class distribution for obtaining an accuracy-trained model. Experimental results demonstrate that the proposed approach achieves high accuracy, sensitivity, specificity, precision, and an F1-score of 97.75%, 97.75%, 99.25%, 97.75%, and 97.75%, respectively, in classifying all the four shockable classes of arrhythmias and are superior to traditional methods. Our work possesses significant clinical value in real-life scenarios since it has the potential to significantly enhance the diagnosis and treatment of life-threatening arrhythmias in individuals with cardiac disease. Furthermore, our model also has demonstrated adaptability and generality for two other datasets.
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  • 文章类型: Journal Article
    情景记忆由两个过程说明:通常识别项目时的“熟悉度”和检索与项目绑定的完整上下文详细信息时的“回忆”。矛盾的是,人们有时报告上下文信息是熟悉的,但不记得细节,这是现有理论不容易解释的。我们测试了项目识别置信度和源记忆的组合,专注于“仅项目点击,来源未知”(“项目熟悉度”),\'具有正确源内存的低置信度命中\'(\'上下文熟悉度\'),和\'具有正确源内存\'的高置信度命中(\'recollection\')。多个受试者内部(试验)和受试者之间(个体差异)水平的结果表明,这些水平在行为和生理上都不同。行为上,交叉交互在响应时间上很明显,在项目识别过程中,上下文熟悉度比每个条件都慢,但在源内存期间更快。电生理,a条件x时间x位置三重解离在事件相关电位(ERP)中是明显的,然后独立复制。上下文熟悉度在800-1200ms内表现出独立的负中心效应,在项目熟悉度(400至600ms)和回忆度(600至900ms)方面与阳性ERP区分开来。因此,这三个条件相互排斥,情节记忆的过程根本不同。语境熟悉是情景记忆的第三个独特过程。
    对过去事件的记忆被广泛认为是通过两个不同的过程来运行的:一个在获取自信时称为“回忆”,记忆的具体细节,另一个叫做“熟悉度”,当只有一种不确定但有意识的意识,即一个项目以前经历过。当人们成功地检索到诸如先前事件的源或上下文之类的详细信息时,它被认为反映了回忆。我们证明了对上下文的熟悉程度在功能上与对项目和回忆的熟悉程度不同,并提供了一个新的三变量模型。三种记忆反应类型在多种行为和生理指标上有区别,在试验水平和受试者之间的个体差异中,也是。也就是说,传统上被认为是两种记忆过程实际上是三种,当使用足够敏感的多措施时,这一点变得很明显。类似于仅使用二维镜头观看三维图片时缺少明显的元素,当我们有能力寻找记忆的三个过程时,我们可以看到它们清晰地分离,并且可以在来自不同实验室的不同队列的几项不同研究中独立复制。一起,这些数据表明,背景熟悉是人类情景记忆的第三过程。
    Episodic memory is accounted for with two processes: \'familiarity\' when generally recognizing an item and \'recollection\' when retrieving the full contextual details bound with the item. Paradoxically, people sometimes report contextual information as familiar but without recollecting details, which is not easily accounted for by existing theories. We tested a combination of item recognition confidence and source memory, focusing upon \'item-only hits with source unknown\' (\'item familiarity\'), \'low-confidence hits with correct source memory\' (\'context familiarity\'), and \'high-confidence hits with correct source memory\' (\'recollection\'). Results across multiple within-subjects (trial-wise) and between subjects (individual variability) levels indicated these were behaviorally and physiologically distinct. Behaviorally, a crossover interaction was evident in response times, with context familiarity being slower than each condition during item recognition, but faster during source memory. Electrophysiologically, a Condition x Time x Location triple dissociation was evident in event-related potentials (ERPs), which was then independently replicated. Context familiarity exhibited an independent negative central effect from 800-1200 ms, differentiated from positive ERPs for item-familiarity (400 to 600 ms) and recollection (600 to 900 ms). These three conditions thus reflect mutually exclusive, fundamentally different processes of episodic memory. Context familiarity is a third distinct process of episodic memory.
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  • 文章类型: Journal Article
    护理行业见证了其挑战和艰难时期的份额,包括有毒或不健康的工作环境,不可持续的工作负载,老龄化的劳动力,人员配备不足,护士倦怠,人员保留,训练有素的工作人员,工作场所暴力的增加,和几个流行病。无论是个人还是集体,这些棘手的问题给护士带来了沉重的负担。不幸的是,许多有能力和称职的护士已经完全离开了这个行业,这进一步加剧了已经有问题的情况。本文重点介绍了几种重要的招聘策略,retaining,并在充满挑战和艰难的时期支持一支高功能的护理人员队伍。
    The nursing profession has witnessed its share of challenging and trying times including toxic or unhealthy work environments, unsustainable workloads, an aging workforce, inadequate staffing, nurse burnout, staff retention, inadequately trained staff, an increase in workplace violence, and several pandemics. Both individually and collectively, these thorny issues have placed a heavy burden on nurses. Unfortunately, many capable and competent nurses have left the profession altogether, which further compounds an already problematic situation. This article highlights several important strategies for recruiting, retaining, and supporting a high functioning nursing workforce in challenging and trying times.
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  • 文章类型: Journal Article
    摩尔斯电码识别在人机交互的应用中起着非常重要的作用。在本文中,基于碳纳米管(CNT)和聚氨酯海绵(PUS)复合材料,开发了一种具有良好压阻特性的柔性触觉CNT/PUS传感器,用于精确检测莫尔斯电码。36种莫尔斯电码,包括26个字母(A-Z)和10个数字(0-9),应用于传感器。每个摩尔斯电码重复60次,收集2160(36×60)组电压时序信号构建数据集。然后,采用平滑和归一化方法对原始数据进行预处理和优化。基于此,构建了具有良好特征提取和自适应能力的长短期记忆(LSTM)模型,以精确识别传感器检测到的不同类型的莫尔斯电码。10号莫尔斯电码的识别精度,26个字母的莫尔斯电码,整个36型摩尔斯电码是99.17%,95.37%,和93.98%,分别。同时,门控经常性单位(GRU),支持向量机(SVM)多层感知器(MLP),和随机森林(RF)模型,以区分36型莫尔斯电码(字母A-Z和数字0-9)基于相同的数据集,并达到91.37%的准确率,88.88%,87.04%,90.97%,分别,均低于基于LSTM模型的93.98%的准确率。实验结果表明,CNT/PUS传感器能够准确检测莫尔斯电码的触觉特性,并且LSTM模型在识别CNT/PUS传感器检测到的摩尔斯电码方面具有非常有效的特性。
    Morse code recognition plays a very important role in the application of human-machine interaction. In this paper, based on the carbon nanotube (CNT) and polyurethane sponge (PUS) composite material, a flexible tactile CNT/PUS sensor with great piezoresistive characteristic is developed for detecting Morse code precisely. Thirty-six types of Morse code, including 26 letters (A-Z) and 10 numbers (0-9), are applied to the sensor. Each Morse code was repeated 60 times, and 2160 (36 × 60) groups of voltage time-sequential signals were collected to construct the dataset. Then, smoothing and normalization methods are used to preprocess and optimize the raw data. Based on that, the long short-term memory (LSTM) model with excellent feature extraction and self-adaptive ability is constructed to precisely recognize different types of Morse code detected by the sensor. The recognition accuracies of the 10-number Morse code, the 26-letter Morse code, and the whole 36-type Morse code are 99.17%, 95.37%, and 93.98%, respectively. Meanwhile, the Gated Recurrent Unit (GRU), Support Vector Machine (SVM), Multi-Layer Perceptron (MLP), and Random Forest (RF) models are built to distinguish the 36-type Morse code (letters of A-Z and numbers of 0-9) based on the same dataset and achieve the accuracies of 91.37%, 88.88%, 87.04%, and 90.97%, respectively, which are all lower than the accuracy of 93.98% based on the LSTM model. All the experimental results show that the CNT/PUS sensor can detect the Morse code\'s tactile feature precisely, and the LSTM model has a very efficient property in recognizing Morse code detected by the CNT/PUS sensor.
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  • 文章类型: Journal Article
    已成功产生了抗蛇毒血清的替代重组来源。这种策略的应用需要对毒液进行表征,以开发针对有毒成分的特定中和分子。通过色谱法在SephadexG-50上进行凝胶过滤,然后在羧甲基纤维素(CMC)树脂上进行离子交换柱,最后通过高效色谱纯化,从墨西哥蝎子中分离出五种对哺乳动物有毒的肽。色谱(HPLC)柱。它们的主要结构由Edman降解决定。它们含有66个氨基酸,并由四个二硫键保持良好的包装,分子量从7511.3到7750.1Da。它们对小鼠都是相对毒性和致命的,并且显示与已知肽的高度序列同一性,所述已知肽是β-毒素(β-ScTx)的Na+离子通道的门控机制的特异性修饰剂。它们被命名为Cv1至Cv5,用于测试它们通过抗体的单链可变片段(scFv)的识别,使用表面等离子体共振。在我们的实验室中产生了三种不同的scFvs(10FG2,HV,LR)被测试识别这里描述的各种新肽,为新型蝎子抗蛇毒血清的发展铺平了道路。
    Alternative recombinant sources of antivenoms have been successfully generated. The application of such strategies requires the characterization of the venoms for the development of specific neutralizing molecules against the toxic components. Five toxic peptides to mammals from the Mexican scorpion Centruroides villegasi were isolated by chromatographic procedures by means of gel filtration on Sephadex G-50, followed by ion-exchange columns on carboxy-methyl-cellulose (CMC) resins and finally purified by high-performance chromatography (HPLC) columns. Their primary structures were determined by Edman degradation. They contain 66 amino acids and are maintained well packed by four disulfide bridges, with molecular mass from 7511.3 to 7750.1 Da. They are all relatively toxic and deadly to mice and show high sequence identity with known peptides that are specific modifiers of the gating mechanisms of Na+ ion channels of type beta-toxin (β-ScTx). They were named Cv1 to Cv5 and used to test their recognition by single-chain variable fragments (scFv) of antibodies, using surface plasmon resonance. Three different scFvs generated in our laboratory (10FG2, HV, LR) were tested for recognizing the various new peptides described here, paving the way for the development of a novel type of scorpion antivenom.
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