PubMed

pubmed
  • 文章类型: Journal Article
    调查研究可以在大型队列中收集有关个人观点的信息。可能是流行病学,专注的态度或知识。目前,文献中缺乏对神经外科医生抽样的调查研究的评估。本研究旨在突出特点,质量,以及发表在神经外科文献中最具影响力的调查研究的引文预测因子。使用PubMed和谷歌学者,对被引用次数最多的50份调查研究出版物进行了鉴定和审查.与物品特征有关的数据,检索参与者和问卷。对研究的质量和引文模式进行了评估。文章年龄中位数和发表期刊影响因子(IF)分别为15.5岁和2.82岁。来自美国的研究人员首次撰写了32篇(64%)文章,而28篇(56%)研究集中在特定的疾病管理上。参与者的中位数和反应率分别为222%和51%,分别。18篇(36%)文章提供了完整版本的问卷。只有四篇(8%)文章报告了问卷的有效性。调查报告的总体质量被认为是公平的(基于五个参数的良好评级,一个参数中的公平评分,四个参数的分级较差)。引用次数中位数为111。引文分析表明,参与者数量,文章年龄(≥15.5岁),和问卷类别(手术并发症)是引文数量的重要预测因素。引用率不受应答率或期刊IF的影响。总之,神经外科文献中的高影响力调查出版物被中等程度地引用并且质量相当.他们的引文数量不受回应率的影响,但受出版年龄的积极影响,参与人数,以及新颖的数据或调查类别中提出的问题。调查是有价值的研究形式,需要广泛的规划,时间,和努力,以产生有意义的结果。提高对可能影响引文的因素的认识可能对那些希望进行调查研究的人有用。
    Survey research enables the gathering of information on individual perspectives in a large cohort. It can be epidemiological, attitude or knowledge focussed. Assessment of survey studies sampling neurosurgeons is currently lacking in the literature. This study aimed to highlight the characteristics, quality, and citation predictors of the most influential survey research studies published in the neurosurgical literature. Using PubMed and Google Scholar, the 50 most cited survey research publications were identified and reviewed. Data relating to the characteristics of the articles, participants and questionnaires were retrieved. The studies\' quality and citation patterns were assessed. The median articles\' age and publishing journal impact factor (IF) were 15.5 years and 2.82, respectively. Thirty-two (64%) articles were first authored by researchers from the USA while 28(56%) studies were focussed on specific disease management. The median number of participants and response rates were 222 and 51%, respectively. A full version of the questionnaire was provided in 18 (36%) articles. Only four (8%) articles reported validation of the questionnaire. The overall quality of reporting of the surveys was considered fair (based on good grading in five parameters, fair grading in one parameter, and poor grading in four parameters). The median citation number was 111. The citation analysis showed that the participant number, article age (≥15.5 years), and questionnaire category (surgical complications) were significant predictors of citation numbers. The citation rates were not influenced by the response rates or the journal\'s IF. In conclusion, high-impact survey publications in the neurosurgical literature were moderately cited and of fair quality. Their citation numbers were not affected by response rates but were positively influenced by the publication age, number of participants, and by novel data or the questions raised in the survey category. Surveys are valuable forms of research that require extensive planning, time, and effort in order to produce meaningful results. Increasing awareness of the factors that could affect citations may be useful to those who wish to undertake survey research.
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  • 文章类型: Editorial
    科学期刊存在的原因是传播科学知识。目标是不断提高出版内容的质量,增加读者数量。在这个意义上,影响因子是一个指标,可以帮助我们可视化我们期刊质量的提高。为了提高这一影响因素,在最常用的数据库中索引是非常重要的。FarmacéuticosComunitarios在几个索引期刊中被索引,但我们缺少最常用的索引。在过去的一年中,我们要求对最重要的索引进行索引,SCOPUS和Medline。11月,我们获得了SCOPUS的批准,并且即将在Medline上获得批准。9月,我们被编辑标准批准,12月被科学家批准。我们只需要技术标准就可以出现在Medline及其在线版本PubMed中。我们正在研究它,很可能在一年内我们将在PubMed中索引。
    The reason for existence of a scientific journal is to disseminate knowledge of science. The objective is a continuous improvement in the quality of what is published and an increase in the number of readers. In this sense, the impact factor is an indicator that helps us visualize the improvement in the quality of our journal. To improve this impact factor, indexing in the most used databases is very important.Farmacéuticos Comunitarios is indexed in several index journals but we were missing the most used ones. In this last year we have requested indexing in the most important ones, SCOPUS and Medline. In November we received SCOPUS approval and are close to getting it on Medline. In September we were approved by the editorial criteria and in December by the scientists. We only need the technical criteria to be able to appear in Medline and in its online version PubMed. We are working on it and it is very likely that within a year we will be indexed in PubMed.
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  • 文章类型: Journal Article
    生物医学关系的自动识别是对已发表文献的非结构化文本中包含的信息进行语义理解的重要步骤。BioCreativeVIII的BioRED曲目旨在通过向参与者提供BioRED-BC8语料库来促进此类方法的发展,为疾病手动策划的1000个PubMed文档集合,基因/蛋白质,化学品,细胞系,基因变异,和物种,以及它们之间的成对关系,这是疾病基因,化学基因,疾病变异,基因-基因,化学疾病,化学化学,化学变体,和变体-变体。此外,关系分为以下语义类别:正相关,负相关,绑定,转换,药物相互作用,比较,共同处理,和协会。与大多数以前公开的语料库不同,所有关系都在文档级别表达,而不是在句子级别表达,因此,将实体标准化为标准化词汇表的相应概念标识符,即,疾病和化学物质被标准化为MeSH,基因(和蛋白质)到国家生物技术信息中心(NCBI)基因,NCBI分类学的物种,细胞系到天龙,和单核苷酸多态性数据库的基因/蛋白质变体。最后,每个注释的关系被归类为\'novel\',这取决于它是一个新的发现或实验验证在出版物中表达。这种区别有助于将新发现与提供已知事实和/或背景知识的同一文本中的其他关系区分开来。BioRED-BC8语料库使用先前的600篇PubMed文章的BioRED语料库作为训练数据集,并包括一组新发布的400篇文章作为挑战的测试数据。所有测试文章都是由国家医学图书馆的专家生物清洁工手动注释的BioCreativeVIII挑战,使用原始注释指南,其中每篇文章都在三轮注释过程中进行双重注释,直到所有策展人之间达成完全协议。本手稿详细介绍了BioRED-BC8语料库作为生物医学命名实体识别和关系提取的关键资源的特征。使用这个新资源,我们已经证明了生物医学文本挖掘算法开发的进步。数据库URL:https://codalab。Lisn.upsaclay.fr/竞赛/16381.
    The automatic recognition of biomedical relationships is an important step in the semantic understanding of the information contained in the unstructured text of the published literature. The BioRED track at BioCreative VIII aimed to foster the development of such methods by providing the participants the BioRED-BC8 corpus, a collection of 1000 PubMed documents manually curated for diseases, gene/proteins, chemicals, cell lines, gene variants, and species, as well as pairwise relationships between them which are disease-gene, chemical-gene, disease-variant, gene-gene, chemical-disease, chemical-chemical, chemical-variant, and variant-variant. Furthermore, relationships are categorized into the following semantic categories: positive correlation, negative correlation, binding, conversion, drug interaction, comparison, cotreatment, and association. Unlike most of the previous publicly available corpora, all relationships are expressed at the document level as opposed to the sentence level, and as such, the entities are normalized to the corresponding concept identifiers of the standardized vocabularies, namely, diseases and chemicals are normalized to MeSH, genes (and proteins) to National Center for Biotechnology Information (NCBI) Gene, species to NCBI Taxonomy, cell lines to Cellosaurus, and gene/protein variants to Single Nucleotide Polymorphism Database. Finally, each annotated relationship is categorized as \'novel\' depending on whether it is a novel finding or experimental verification in the publication it is expressed in. This distinction helps differentiate novel findings from other relationships in the same text that provides known facts and/or background knowledge. The BioRED-BC8 corpus uses the previous BioRED corpus of 600 PubMed articles as the training dataset and includes a set of newly published 400 articles to serve as the test data for the challenge. All test articles were manually annotated for the BioCreative VIII challenge by expert biocurators at the National Library of Medicine, using the original annotation guidelines, where each article is doubly annotated in a three-round annotation process until full agreement is reached between all curators. This manuscript details the characteristics of the BioRED-BC8 corpus as a critical resource for biomedical named entity recognition and relation extraction. Using this new resource, we have demonstrated advancements in biomedical text-mining algorithm development. Database URL: https://codalab.lisn.upsaclay.fr/competitions/16381.
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  • 文章类型: Journal Article
    在神经科学中,概念在研究的概念和方向中起着重要作用。在理论概念和研究方向中,可塑性之所以突出,是因为科学家用它来描述和解释神经系统如何变化和适应不同需求的多种方式。使用文献计量学方法研究了20世纪下半叶到目前为止科学文献中可塑性不同概念化的发生。在整个分析期间,突触可塑性仍然是可塑性的主要概念化。然而,科学家们不断引入新的可塑性概念,反映了他们在理解神经系统动态性质方面取得的科学进步。可塑性的概念演变证明,成人神经系统不可变的观点已被对神经系统能够终生改变和适应的理解所取代。
    In the neurosciences, concepts play an important role in the conception and direction of research. Among the theoretical notions and direction of research, plasticity stands out because of the multiple ways in which scientists use it to describe and interpret how the nervous system changes and adapts to different requirements. The occurrence of different conceptualizations of plasticity in the scientific literature during the second half of the twentieth century and up to the present was investigated using bibliometric methods. Throughout the period analyzed, synaptic plasticity has remained the dominant conceptualization of plasticity. However, scientists have continued to introduce novel plasticity concepts reflecting the scientific advances they have made in understanding the dynamic nature of the nervous system. The conceptual evolution of plasticity documents that the view of the adult nervous system as immutable has been replaced by an understanding of the nervous system as capable of lifelong change and adaptation.
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  • 文章类型: Case Reports
    库提供对数据库的访问,这些数据库具有嵌入到服务中的自动引用功能;但是,在人文和社会科学数据库中,这些自动引用按钮的准确性不是很高。
    这个案例比较了两个生物医学数据库,OvidMEDLINE和PubMed,看看两者是否足够可靠,可以自信地推荐给学生在写论文时使用。总共评估了60篇引文,每个引文生成器引用30次,基于2010年至2020年PubMed排名前30位的文章。
    OvidMEDLINE的错误率高于PubMed,但两个数据库平台均未提供无错误引用。自动引用工具不可靠。所检查的60篇引文中有0篇是100%正确的。图书馆员应继续建议学生不要仅依赖这些生物医学数据库中的引文生成器。
    UNASSIGNED: Libraries provide access to databases with auto-cite features embedded into the services; however, the accuracy of these auto-cite buttons is not very high in humanities and social sciences databases.
    UNASSIGNED: This case compares two biomedical databases, Ovid MEDLINE and PubMed, to see if either is reliable enough to confidently recommend to students for use when writing papers. A total of 60 citations were assessed, 30 citations from each citation generator, based on the top 30 articles in PubMed from 2010 to 2020.
    UNASSIGNED: Error rates were higher in Ovid MEDLINE than PubMed but neither database platform provided error-free references. The auto-cite tools were not reliable. Zero of the 60 citations examined were 100% correct. Librarians should continue to advise students not to rely solely upon citation generators in these biomedical databases.
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  • 文章类型: Journal Article
    目的:通过在医学主题词(MeSH)中添加新的健康社会决定因素(SDoH)术语,提高和评估PubMed搜索结果的质量。
    方法:高优先级的SDoH术语和定义是从权威来源整理的,根据出版频率策划,并由主题专家提炼。描述性分析用于调查PubMed搜索细节和最佳匹配结果如何受到添加到MeSH的SDoH概念的影响。三个信息检索指标(Precision,回想一下,和F度量)用于定量评估PubMed搜索结果的准确性。使用自然语言处理管道将更新前和更新后的文档聚集到主题区域中,和SDoH相关性评估。
    结果:将35个SDoH术语添加到MeSH中,可以获得更准确的搜索词算法翻译和更可靠的最佳匹配结果。精度,回想一下,更新后结果的F指标显着高于更新前结果的F指标。在更新后搜索中,属于SDoH群集的检索出版物的百分比明显高于更新前搜索。
    结论:该评估证实,在MeSH中加入新的SDoH术语可以导致PubMed搜索检索的定性和定量增强。它展示了为MeSH索引提出新术语的方法和影响。它为行为和社会科学研究(BSSR)领域的未来努力提供了基础。
    结论:改善MeSH中BSSR术语的表示可以改善PubMed搜索结果,从而提高研究人员和临床医生建立和利用累积BSSR知识库的能力。
    OBJECTIVE: To enhance and evaluate the quality of PubMed search results for Social Determinants of Health (SDoH) through the addition of new SDoH terms to Medical Subject Headings (MeSH).
    METHODS: High priority SDoH terms and definitions were collated from authoritative sources, curated based on publication frequencies, and refined by subject matter experts. Descriptive analyses were used to investigate how PubMed search details and best match results were affected by the addition of SDoH concepts to MeSH. Three information retrieval metrics (Precision, Recall, and F measure) were used to quantitatively assess the accuracy of PubMed search results. Pre- and post-update documents were clustered into topic areas using a Natural Language Processing pipeline, and SDoH relevancy assessed.
    RESULTS: Addition of 35 SDoH terms to MeSH resulted in more accurate algorithmic translations of search terms and more reliable best match results. The Precision, Recall, and F measures of post-update results were significantly higher than those of pre-update results. The percentage of retrieved publications belonging to SDoH clusters was significantly greater in the post- than pre-update searches.
    CONCLUSIONS: This evaluation confirms that inclusion of new SDoH terms in MeSH can lead to qualitative and quantitative enhancements in PubMed search retrievals. It demonstrates the methodology for and impact of suggesting new terms for MeSH indexing. It provides a foundation for future efforts across behavioral and social science research (BSSR) domains.
    CONCLUSIONS: Improving the representation of BSSR terminology in MeSH can improve PubMed search results, thereby enhancing the ability of investigators and clinicians to build and utilize a cumulative BSSR knowledge base.
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  • 文章类型: Journal Article
    心理健康状况,比如抑郁症,焦虑,和压力相关的疾病,通常很难使用传统方法进行诊断和监测。唾液生物标志物提供了一个有希望的替代由于其非侵入性的性质,易于收集,以及反映与心理健康相关的实时生理变化的潜力。这项文献计量分析检查了95项关于心理健康压力生物标志物的临床试验,2003年至2024年出版。该领域的特点是广泛合作和全球参与,涉及73种期刊的593位作者和出版物。尽管每年的出版率一致,2011年、2014年和2018年的显着增长表明研究兴趣不断增长。美国的研究成果领先,其次是澳大利亚,德国,和日本,精神神经内分泌学是最著名的杂志。共现分析确定了九个研究集群,提出了不同的方向,比如压力相关激素的影响,昼夜节律,正念,各种疗法,老化,心理适应机制,运动疗法,焦虑症,和唾液生物标志物上的自主神经系统。关键术语,如“生物标志物/新陈代谢,“和”氢化可的松/新陈代谢,“和”唾液/新陈代谢“是中心,从2012年到2018年有重大活动。该分析强调了对唾液生物标志物在心理健康中的代谢过程和治疗应用的日益关注。这项文献计量分析呼吁关注唾液生物标志物通过非侵入性方法彻底改变心理健康诊断和治疗的潜力,促进跨学科研究,技术进步,和全球健康改善。
    Mental health conditions, such as depression, anxiety, and stress-related disorders, are often difficult to diagnose and monitor using traditional methods. Salivary biomarkers offer a promising alternative due to their non-invasive nature, ease of collection, and the potential to reflect real-time physiological changes associated with mental health. This bibliometric analysis examines 95 clinical trials on stress biomarkers for mental health, published between 2003 and 2024. The field is characterized by extensive collaboration and global participation, involving 593 authors and publications across 73 journals. Despite a consistent annual publication rate, notable increases in 2011, 2014, and 2018 indicate growing research interest. The United States leads in research output, followed by Australia, Germany, and Japan, with Psychoneuroendocrinology being the most prominent journal. Co-occurrence analysis identified nine research clusters, suggesting diverse directions such as the impact of stress-related hormones, circadian rhythms, mindfulness, various therapies, aging, psychological adaptation mechanisms, exercise therapy, anxiety disorders, and the autonomic nervous system on salivary biomarkers. Key terms such as \"biomarkers/metabolism,\" AND \"hydrocortisone/metabolism,\" AND \"saliva/metabolism\" were central, with significant activity from 2012 to 2018. This analysis highlights a growing focus on the metabolic processes and therapeutic applications of salivary biomarkers in mental health. This bibliometric analysis calls attention to the promising potential of salivary biomarkers to revolutionize mental health diagnostics and treatment through non-invasive methods, fostering interdisciplinary research, technological advancements, and global health improvements.
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  • 文章类型: Journal Article
    生物医学和生命科学的出版物数量增长如此之多,以至于很难跟踪新的科学作品,也很难对整个领域的发展进行概述。这里,我们提供了整个生物医学文献语料库的二维(2D)图,基于PubMed数据库中2100万篇英文文章的摘要文本。要将摘要嵌入到2D中,我们使用了大型语言模型PubMedBERT,结合为处理这种大小的样品而定制的t-SNE。我们用我们的图谱研究了COVID-19文献的出现,神经科学学科的演变,机器学习的吸收,学术作者身份中性别失衡的分布,以及收回的造纸厂物品的分配。此外,我们提供了一个交互式网站,可以轻松探索,并将使进一步的见解和促进未来的研究。
    The number of publications in biomedicine and life sciences has grown so much that it is difficult to keep track of new scientific works and to have an overview of the evolution of the field as a whole. Here, we present a two-dimensional (2D) map of the entire corpus of biomedical literature, based on the abstract texts of 21 million English articles from the PubMed database. To embed the abstracts into 2D, we used the large language model PubMedBERT, combined with t-SNE tailored to handle samples of this size. We used our map to study the emergence of the COVID-19 literature, the evolution of the neuroscience discipline, the uptake of machine learning, the distribution of gender imbalance in academic authorship, and the distribution of retracted paper mill articles. Furthermore, we present an interactive website that allows easy exploration and will enable further insights and facilitate future research.
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  • 文章类型: Journal Article
    背景:对基于证据的医疗决策的高质量系统文献综述(SRs)的需求正在增长。SR成本很高,需要高技能审稿人的稀缺资源。已经提出了自动化技术来节省工作量并加快SR工作流程。我们旨在全面概述PubMed索引的SR自动化研究,专注于这些技术在现实世界实践中的适用性。
    方法:2022年11月,我们提取,合并,并在SR自动化上运行了对SR的集成PubMed搜索。全文包括英文同行评审文章,如果他们报告了对SR自动化方法(SSAM)的研究,或自动SR(ASR)。书目分析和知识发现研究被排除在外。记录筛选由单个审阅者进行,全文论文的选择一式两份。我们总结了出版物的细节,自动审查阶段,自动化目标,应用工具,数据源,方法,结果,和谷歌学者对SR自动化研究的引用。
    结果:根据标题和摘要筛选的5321条记录,我们收录了123篇全文,其中SSAM108个,ASR15个。自动化用于搜索(19/123,15.4%),记录筛查(89/123,72.4%),全文选择(6/123,4.9%),数据提取(13/123,10.6%),偏见风险评估(9/123,7.3%),证据综合(2/123,1.6%),证据质量评估(2/123,1.6%),和报告(2/123,1.6%)。11项(8.9%)研究将多个SR阶段自动化。自动记录筛选的性能在SR主题中差异很大。在已发布的ASR中,我们找到了自动搜索的例子,记录筛选,全文选择,和数据提取。在某些ASR中,自动化完全补充了手动审核,以提高灵敏度,而不是节省工作量。在ASR中,自动化详细信息的报告通常是不完整的。
    结论:正在为所有SR阶段开发自动化技术,但现实世界的采用率有限。大多数SR自动化工具以单个SR阶段为目标,在整个SR过程中节省了适度的时间,并且在研究中具有不同的灵敏度和特异性。因此,SR自动化的实际好处仍然不确定。标准化术语,reporting,和研究报告的指标可以增强SR自动化技术在现实世界实践中的采用。
    BACKGROUND: The demand for high-quality systematic literature reviews (SRs) for evidence-based medical decision-making is growing. SRs are costly and require the scarce resource of highly skilled reviewers. Automation technology has been proposed to save workload and expedite the SR workflow. We aimed to provide a comprehensive overview of SR automation studies indexed in PubMed, focusing on the applicability of these technologies in real world practice.
    METHODS: In November 2022, we extracted, combined, and ran an integrated PubMed search for SRs on SR automation. Full-text English peer-reviewed articles were included if they reported studies on SR automation methods (SSAM), or automated SRs (ASR). Bibliographic analyses and knowledge-discovery studies were excluded. Record screening was performed by single reviewers, and the selection of full text papers was performed in duplicate. We summarized the publication details, automated review stages, automation goals, applied tools, data sources, methods, results, and Google Scholar citations of SR automation studies.
    RESULTS: From 5321 records screened by title and abstract, we included 123 full text articles, of which 108 were SSAM and 15 ASR. Automation was applied for search (19/123, 15.4%), record screening (89/123, 72.4%), full-text selection (6/123, 4.9%), data extraction (13/123, 10.6%), risk of bias assessment (9/123, 7.3%), evidence synthesis (2/123, 1.6%), assessment of evidence quality (2/123, 1.6%), and reporting (2/123, 1.6%). Multiple SR stages were automated by 11 (8.9%) studies. The performance of automated record screening varied largely across SR topics. In published ASR, we found examples of automated search, record screening, full-text selection, and data extraction. In some ASRs, automation fully complemented manual reviews to increase sensitivity rather than to save workload. Reporting of automation details was often incomplete in ASRs.
    CONCLUSIONS: Automation techniques are being developed for all SR stages, but with limited real-world adoption. Most SR automation tools target single SR stages, with modest time savings for the entire SR process and varying sensitivity and specificity across studies. Therefore, the real-world benefits of SR automation remain uncertain. Standardizing the terminology, reporting, and metrics of study reports could enhance the adoption of SR automation techniques in real-world practice.
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  • 文章类型: Journal Article
    目标:定期,医学出版物被撤回。原因因小而异,如作者归因,这不会损害数据的有效性或文章中的分析,出于严重的原因,比如欺诈。了解撤回的原因可以为临床医生提供重要信息,教育工作者,研究人员,期刊,和编辑委员会。
    方法:使用术语“COVID-19”(2019年冠状病毒病)和术语“限制”撤回出版物搜索PubMed数据库。“撤回文章的期刊的特点,文章的类型,并分析了回撤的原因。
    结果:此搜索恢复了已撤回的196篇文章。这些撤回发表在179种不同的期刊上;14种期刊有>1篇撤回的文章。这些期刊的平均影响因子为8.4,范围为0.32-168.9。撤回的最常见原因是重复出版,对数据有效性和分析的担忧,对同行评审的担忧,作者请求,以及缺乏许可或违反道德的行为。文章类型和回缩原因之间存在显着差异,但没有一致的模式。对两个特定撤回的更详细的分析表明,对文章撤回做出决定所需的复杂性和工作量。
    结论:撤回已发表的文章对期刊提出了重大挑战,编辑委员会,同行审稿人,和作者。这个过程有可能提供重要的好处;它也有可能破坏人们对研究和编辑过程的信心。
    OBJECTIVE: Periodically, medical publications are retracted. The reasons vary from minor situations, such as author attributions, which do not undermine the validity of the data or the analysis in the article, to serious reasons, such as fraud. Understanding the reasons for retraction can provide important information for clinicians, educators, researchers, journals, and editorial boards.
    METHODS: The PubMed database was searched using the term \"COVID-19\" (coronavirus disease 2019) and the term limitation \"retracted publication.\" The characteristics of the journals with retracted articles, the types of article, and the reasons for retraction were analyzed.
    RESULTS: This search recovered 196 articles that had been retracted. These retractions were published in 179 different journals; 14 journals had >1 retracted article. The mean impact factor of these journals was 8.4, with a range of 0.32-168.9. The most frequent reasons for retractions were duplicate publication, concerns about data validity and analysis, concerns about peer review, author request, and the lack of permission or ethical violation. There were significant differences between the types of article and the reasons for retraction but no consistent pattern. A more detailed analysis of two particular retractions demonstrates the complexity and the effort required to make decisions about article retractions.
    CONCLUSIONS: The retraction of published articles presents a significant challenge to journals, editorial boards, peer reviewers, and authors. This process has the potential to provide important benefits; it also has the potential to undermine confidence in both research and the editorial process.
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